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Explore America’s Most Iconic Waterways With the 5 Best U.S. River Cruises

Discover natural and cultural treasures close to home.

You don't need to fly to Europe for a river cruise, with new ships and routes creating even more options right here in the United States. Some of the most scenic itineraries traverse the Mississippi, Hudson, Columbia, and Snake rivers, showcasing natural, cultural, and historical attractions along the way. Passengers can visit wineries in Washington, taste Creole cuisine in New Orleans, or learn about the Siege of Vicksburg right where it happened.

On these voyages, you'll sail with anywhere from 100 to 400 other guests aboard either modern riverboats or classic paddle wheelers that hearken back to a different time. Like their European counterparts, river cruises in the U.S. typically package everything at a single price, including staterooms, meals, guest lectures and enrichment programs, entertainment, and most shore excursions. Some even include pre-cruise hotel stays.

Here are five river cruises that will show you the U.S. in a whole new light.

American Cruise Lines’ Music Cities Cruise from Memphis to Nashville

It's hard to choose from American Cruise Lines' 35 itineraries. For arts and culture lovers, the eight-day Music Cities Cruise along the Mississippi, Ohio, and Cumberland rivers presents an opportunity to visit several charming cities and towns in the South. The itinerary is offered on four different 180-passenger ships, including the American Serenade and the classic American Splendor paddle wheeler.

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The voyage begins in Memphis, where passengers can visit the Stax Museum of American Soul Music, take in a show at one of the nightclubs along legendary Beale Street, or tour Elvis Presley's mansion, Graceland. After a day of cruising, the ship stops at Paducah, Kentucky, where you can admire the more than 50 murals on the floodwall along Water Street before exploring the National Quilt Museum. The next day, the ship travels through the Barkley Lock and past the stunning coves and limestone bluffs of the Cumberland River's Lake Barkley– a view best enjoyed from the balcony of your stateroom. In Dover, Tennessee, guests visit historic Fort Donelson National Park and learn about the garrison's role during the Civil War. The next day, passengers can tour the Customs House Museum & Cultural Center and Fort Defiance in Clarksville, Tennessee, and cap off the experience with a whiskey tasting at Old Glory Distilling Co. The voyage ends in Nashville, where you can stroll along historic Lower Broadway, visit museums dedicated to Johnny Cash and Patsy Cline, and take in a Grand Ole Opry show. 

American Queen Voyages' Upper Mississippi Cruise from St. Louis to Minneapolis

History buffs will love this nine-day cruise along the Upper Mississippi and Illinois rivers aboard American Queen Voyages' 245-passenger American Countess paddle wheeler. The itinerary offers guests a chance to explore the idyllic river towns that inspired the Father of American Literature.

After departing St. Louis, the cruise arrives in Alton, Illinois, where guests can play golf on championship courses, explore the National Great Rivers Museum , or just stroll around the town's historic districts. Day three brings passengers further upriver to Mark Twain's hometown of Hannibal, Missouri, from which the author drew inspiration for several of his novels. On day four, the ship stops at Bettendorf, Iowa, for a hop-on hop-off tour of museums, artist studios, the German American Heritage Center , and the Quad City Botanical Center . In Dubuque, Iowa, guests can take a ride on the Fenelon Place Elevator, billed as "the world's steepest, shortest scenic railway". Day nine, finds the the ship at La Crosse, Wisconsin, famous for its rugged terrain and breathtaking vistas. The final port is Red Wing, Minnesota, home to beautifully preserved artisan workshops, factories, and pioneer-era architecture. After disembarking, passengers can explore nearby Minneapolis before going home.

American Cruise Lines’ Hudson River Fall Foliage Cruise

This eight-day fall foliage-themed cruise takes leaf peeping to a new level. The round-trip voyage out of New York City takes nature lovers through the heart of the Hudson Valley  –  swathed every fall in a blanket of bright orange, red, and yellow. Whether you sail on the classic 48-stateroom American Star or the 100-passenger American Eagle , you'll enjoy a stunning display of colors from the comfort of your balcony. On shore, you’ll have the opportunity to hike to the highest waterfall in the Empire State , walk across the longest pedestrian bridge in the world , and visit the homes of Franklin D. Roosevelt in Hyde Park and author Washington Irving in Sleepy Hollow.

Viking Cruises’ New Orleans & Southern Charms Lower Mississippi Cruise

This eight-day round-trip cruise takes in historic estates, military sites, and comunities bursting with Cajun and Creole culture. After departing New Orleans, the Viking Mississippi stops in the Louisiana towns of Darrow and St. Francisville, which boast Greek Revival mansions, Spanish moss-draped avenues, and even a haunted house . Day four brings travelers to the oldest city on the river, Natchez, Mississippi, home to a rich African American heritage . The next day, guests can learn about one of the most consequential battles of the Civil War at Vicksburg National Military Park before setting sail for the vibrant capital city of Baton Rouge, Louisiana. The ship then returns to New Orleans, where guests can stay longer or catch a flight home.

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UnCruise Adventures’ Rivers of Adventure & Wine Columbia and Snake River Cruise

Spotting wildlife and sipping wine go hand-in-hand on this UnCruise Adventures expedition around the Pacific Northwest. The seven-night round-trip journey from Portland isn't your typical leisure cruise. Instead, passengers get to go on rainforest hikes, rafting adventures, winery visits, and scenic kayaking excursions through dramatic canyons.

After the champagne departure from Portland and a stop at Astoria, Oregon, the ship passes through the Columbia River Gorge. Passengers can disembark for a guided hike, then return for a wine tasting with the ship's sommelier. The gourmand adventures continue with an excursion to Walla Walla, Washington, which includes visits to olive oil makers, chocolatiers, and family-owned wine cellars. Day five begins at the mouth of the Palouse River, where guests can kayak or paddleboard. The next day, passengers can visit Columbia Hills State Park and Rowena Plateau on foot or by skiff boat while enjoying river dips, farm-to-fork delights, and a wine tour and tasting. Guests then disembark at The Dalles, Oregon, for whitewater rafting or a relaxing winery tour. The adventure ends with a farewell dinner back at Portland.

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7 best US river cruises

Whether you're fascinated by American history, culture and cuisine, or you've enjoyed river cruising in Europe but are now looking to explore closer to home, U.S. river cruises are an easy and enjoyable vacation option.

Choose from two main waterways for your U.S. river cruise: the Mississippi River — which flows through nine states from St. Paul, Minnesota, to New Orleans — or the Columbia and Snake rivers in Oregon and Washington. Some cruise lines also venture onto three smaller, lesser-known rivers: the Ohio, the Cumberland and the Tennessee. You can also explore New York's Hudson River on a fall foliage cruise.

For cruise news, reviews and tips, sign up for TPG's cruise newsletter .

Your choice of cruise line is equally limited. Just two companies offer multiple itineraries on U.S. rivers. American Cruise Line sails all the waterways mentioned above, while Viking offers itineraries solely on the Mississippi. Additionally, Lindblad Expeditions has introduced a food-and-wine-centric river cruise on the Columbia and Snake rivers.

Read on for our picks of the seven best U.S. river cruises. They range from seven to 15 nights and visit destinations in 16 states; itineraries take you through the colonial-heritage-rich Northeast, America's agricultural heartland and the pioneer routes of the Pacific Northwest.

American Cruise Lines' 8-night Music Cities Cruise

From Memphis blues and Elvis Presley's "Blue Suede Shoes" to Kentucky bluegrass and New Orleans jazz, American Cruise Lines' eight-night Music Cities Cruise sails you through a chronology of the U.S. music scene. You'll traverse three rivers (the Mississippi, Ohio and Cumberland) en route from Memphis to Nashville, or vice versa.

In Tennessee's two famous music cities, you'll have a chance to visit Elvis Presley's Graceland, stroll blues club-lined Beale Street and check out the Grand Ole Opry. You'll also visit Paducah, Kentucky, and Dover and Clarksville in Tennessee, where experiences include whiskey and bourbon tasting, tours of landmark art murals and, of course, Civil War history.

While cruising, you'll enjoy nightly entertainment that celebrates the region's musical heritage. American Cruise Lines offers this itinerary on four ships from April to October 2024, 2025 and 2026. Three of the ships — American Melody, American Symphony and American Serenade — are 180-passenger modern river ships launched in 2021, 2022 and 2023, respectively. The fourth, American Splendor, is a 180-passenger paddlewheeler that debuted in 2016.

Related: Booking your first river cruise? Here's what you need to know

Viking's 14-night America's Great River Cruise

Want the total Mississippi experience? You can cruise the entire length of this mighty river as you visit 14 cities in seven U.S. states on Viking's two-week sailing.

Available three times a year (in July, September and October), the America's Great River cruise begins in Minnesota (either St. Paul or Red Wing) and concludes in New Orleans, allowing you to experience an intricate tapestry of American history and culture.

There's eagle spotting in Red Wing and agricultural innovation in Quad Cities, Iowa. You'll enjoy Mark Twain lore in Hannibal, Missouri, and architectural landmarks, such as the soaring Gateway Arch, in St. Louis. As you cruise the lower Mississippi, you'll delve into civil rights history in Memphis; Civil War battles and historic architecture in Mississippi's Vicksburg and Natchez; Cajun and Creole music in Baton Rouge; and the legendary culinary treats and jazz of New Orleans.

All sailings are aboard the 386-passenger Viking Mississippi. Launched in 2022, it's currently the largest river ship in the U.S. and features three restaurants and an aft infinity pool.

American Cruise Lines' 8-Night Columbia & Snake River Cruise

If your vacation preferences favor mountain landscapes, wine tasting and pioneer lore, consider American Cruise Lines' eight-night Columbia & Snake River Cruise . You'll explore the Pacific Northwest from Portland, Oregon, to Clarkstown, Washington (or vice versa).

On the Pacific end of your voyage, you'll visit Astoria, Oregon — the oldest American settlement west of the Rocky Mountains. This coastal city at the mouth of the Columbia River is known for its Victorian homes, wineries, brew pubs, and Lewis and Clark heritage. Next, from Kalama, Washington, you can join an excursion to visit the remnants of the area around Mount St. Helens, which suffered a devastating eruption in 1980.

In The Dalles, you can enjoy a sommelier-led tasting of Columbia Valley wines, visit Multnomah Falls or get adventurous on a river kayak tour. During a call on Richland, Washington, you can admire the scenic beauty around the confluence of the Columbia and Snake rivers at Sacajawea State Park. More wine tasting or outdoor adventure awaits on the way to Clarkstown.

American Cruise Line offers this itinerary on five ships from April to October 2024, 2025 and 2026. Three of the ships (American Song, American Jazz and American Harmony) are 180-passenger modern river ships launched from 2018 to 2020. American Pride is a 150-passenger paddlewheeler launched in 2012, and American West is a 110-passenger veteran paddlewheeler launched in 1995.

Related: Best river cruise lines around the world

Viking's 7-night New Orleans & Southern Charms

If you've never visited New Orleans, or it's been a while, take a Mississippi River cruise that sails round-trip from the Big Easy. They offer time before or after the cruise to enjoy the city's food, music and iconic architecture — plus the ease of a round-trip flight booking. Viking's seven-night New Orleans & Southern Charms itinerary focuses solely on ports in Louisiana and Mississippi, with an emphasis on historic architecture, Cajun culture and Civil War landmarks.

From Darrow, Louisiana, you'll stroll beneath canopies of towering live oak trees to visit historic mansions or glide through the bayou. More historic architecture, along with bird-watching, awaits in St. Francisville, Louisiana, and Natchez, Mississippi. Vicksburg, Mississippi, is home to one of the Civil War's most famous battlefields. Baton Rouge, Louisiana's capital, has something to satisfy every interest, from Cajun cuisine to tours of the restored World War II-era USS Kidd.

The cruise, which is available in November and December 2024 and January, November and December 2025, ends with a full day of exploration back in New Orleans before one last night aboard the 386-passenger Viking Mississippi.

American Cruise Lines' 7-night Hudson River Fall Foliage Cruise

Not only is the autumnal landscape in New York's Hudson Valley visually captivating, but the small cities and towns that line the river's shores are filled with fascinating early American history dating back more than 400 years.

Cruise the Hudson round-trip from New York City on American Cruise Lines' seven-night Hudson River Fall Foliage Cruise . You'll visit Catskill, home to the Hudson River School Art Trail and the Olana Historic Site, or explore more actively at the Hudson River Skywalk and Kaaterskill Falls. In Albany, founded in 1609, you can tour the newly renovated New York State Capitol building, built in the late 1800s; you can also visit the New York State Museum, which dates to 1836. Feel like apple-picking? That's an option here, too.

Next, during a call at Kingston/Hyde Park, you can tour the Franklin D. Roosevelt National Historic Site, home to the 32nd U.S. president's library and museum. You can also head to the Vanderbilt Mansion National Historic Site, featuring an American Beaux-Arts mansion completed in 1899. The United States Military Academy at West Point, founded in 1802, is also on the itinerary, as is Sleepy Hollow. The Sleepy Hollow legend comes to life during a tour of the local cemetery where author Washington Irving is buried. Back in the Big Apple on day seven, you'll have time to explore before saying farewell to your ship.

Sailings are available from late September to early November 2024, 2025 and 2026. Sailings are onboard either the 100-passenger American Eagle, American Liberty, American Glory or American Legend (all built in 2023 or 2024), or the older 90-passenger American Star and American Independence, launched in 2007 and 2010, respectively.

Related: River cruise packing list: What to pack when traveling by riverboat

Lindblad Expeditions' 7-night Columbia & Snake Rivers: Food, Wine and History Cruise

Nature-focused cruise line Lindblad Expeditions has partnered with Food & Wine magazine to offer a new seven-night Columbia & Snake Rivers: Food, Wine and History cruise on multiple dates in April, September and October 2024; there are also sailings in March, April, September and October 2025. The voyages will sail between Portland, Oregon, and Clarkston, Washington.

Complementing the itinerary will be gourmet Pacific Northwest cuisine and more than 40 regional wines curated by an onboard culinary team. All ingredients will be sourced from within 250 miles of the ship's route. A naturalist, historian and geologist will be on hand to guide you on excursions by foot, kayak, Zodiac and jet boat.

Off-ship experiences include sampling local beer and oysters in Astoria, Oregon; visiting Multnomah Falls or hiking Beacon Rock; and having a private vineyard visit and downtown wine walk in Walla Walla, Washington.

These sailings occur on two identical Lindblad ships: the 62-passenger National Geographic Sea Lion and National Geographic Sea Bird.

American Cruise Line's 15-night Grand Ohio River Cruise

Did you know that you can cruise from Pittsburgh to St. Louis? If exploring the central U.S. — Pennsylvania, Ohio, West Virginia, Kentucky, Indiana, Illinois and Missouri — without driving is appealing, consider the 15-night Grand Ohio River Cruise offered by American Cruise Lines. You'll enjoy regionally inspired dining and eclectic landmarks along the Ohio and Mississippi rivers as you sail.

Over two weeks, you'll visit Native American burial grounds and archeological sites in West Virginia and learn about the underground railroad in Ohio. You can taste bourbon and explore the Louisville Slugger Museum & Factory or the Kentucky Derby Museum & Horse Park in Louisville. Take time to appreciate American artistry at the National Quilt Museum in Paducah, Kentucky. Rest up from your portside adventures during five days of scenic river cruising.

This itinerary is available from June to August 2024, 2025 and 2026 on the 180-passenger modern river ship American Melody and the 150-passenger paddlewheeler American Heritage.

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Brand new ship the  American Jazz on Lower Mississippi just in time for the holidays Nov and Dec. Special offer $1500 off a cabin. Offer good until June 30th.

Current sold-out dates are Nov. 17th and 24th on the American Harmony.

Columbia & Snake River Cruise – The American Song : a brand new, modern riverboat that is now cruising the Columbia and Snake Rivers between Washington and Oregon offering iconic NW cruises.

Northwest Pioneers: 10-night Columbia River Cruise – American Pride : Our 7-night Columbia River cruises are popular every year, but so often we want just a little more time to explore! The new ‘Northwest Pioneers’ itinerary affords you that time to dig a little deeper.

These are smaller ships and they tend to sell out months ahead of time! These offers must be booked by July 31st.

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Last but certainly not least: USA River Cruises takes the guesswork out of planning a trip in the first place. You’ll no longer have to fret over the cost of every little perk — because the perks are part of the all-inclusive experience aboard a USA River Cruise. No need to tally up the numbers when you order beer, a glass of wine, room service, soda, cappuccinos, or decide to take a shore excursion.

The world is waiting for you. Imagine your most wonderful journey. Then contact USA River Cruises to make it come true.

Ever thought about a VIP-style, front row seat to breathtaking waterfalls, rolling vineyards, and stunning mountain peaks? Try one of our Columbia River Cruises.

Envision paradise, adventure and relaxation with USA River Cruises

Imagine exploring the ins and outs of the largest group of freshwater lakes on earth — and then hop aboard our Great Lakes River Cruises .

Perhaps you’ve always wondered what it would be like to explore the Deep South in comfort and style. Our Mississippi River Cruises are the place to be.

Or maybe you’ve always wanted to experience Europe from a ship’s-eye view. Well USA River Cruises has those, too, with our sweet suite of European Cruises .

There’s so much for you to see and do. From the Great Lakes and the mighty Mississippi to the Columbia River and our Alaskan Cruises ports of call — all the way to our cruises throughout Europe and the Caribbean.

USA River Cruises has been making travel dreams come true since 1999. We’re experts at matching people with the experiences they seek. There’s something for everyone. There’s something for you.

“This Columbia River Cruise experience was a total delight, very informative, educational, entertaining, and just a fantastic experience overall. Every port offered opportunities for exploration and learning. The on-board Riverlorian brought history to life, as did the local entertainment brought onboard. The cuisine selections and quality were top-shelf all the way.”

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Mississippi River Cruises

Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, our new cruises on the "Mighty Mississippi" offer a different type of cross-country journey for the curious explorer—one that allows you to be immersed in American history and culture.

Step on board the newest and most modern ship on the Mississippi with all outside staterooms, private verandas, spacious public areas and our signature, clean Scandinavian design, reimagined for the Mississippi River.

NEW! Mississippi Delta Explorer

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America’s Heartland

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Highlights of mississippi river cruises.

A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port. Here are a few highlights Viking reveals to you:

• Festive French Quarter and Creole cuisine in New Orleans
• Cajun heritage in Baton Rouge
• Civil War history at Vicksburg National Military Park
• Memphis BBQ, Graceland and appreciation of the Delta Blues
• Steamboat sailings with diverse wildlife sightings
• Mark Twain's boyhood home and America’s literary history
• Up close look at America’s national symbol, the bald eagle
• Gateway Arch in St. Louis and the pioneering spirit of the Midwest
• Norwegian cultural experience at Vesterheim
• Intricate locks and dams of the Upper Mississippi

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