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Study abroad flyer template
Advertise your next university event or ongoing college program with this flyer template. A large photo helps draw attention to the possibilities of an exciting study abroad while the copy layout provides ample room to describe the details of the program. Customize the template to match your needs with our intuitive editor.
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How to Make a Research Study Flyer
Identify the purpose of the research study flyer, define the target audience for the flyer, decide on the main messages to be communicated in the flyer, choose the size and format of the flyer.
- 1 8.5 x 11 inches (Letter)
- 2 5.5 x 8.5 inches (Half-Letter)
- 5 Custom size
Approval: Format Decision
- Choose the size and format of the flyer Will be submitted
Design the flyer layout and graphics
Write eye-catching headline, create content for the flyer that details the research study, incorporate call to action, proofread and edit the text for clarity and accuracy, approval: content clarity.
- Create content for the flyer that details the research study Will be submitted
Insert necessary contact information and/or RSVP details
Approval: contact information.
- Insert necessary contact information and/or RSVP details Will be submitted
Review and adjust the flyer design
Print a test copy of the flyer.
- 1 Print in color
- 2 Print in black and white
- 3 Print single-sided
- 4 Print double-sided
- 5 Print multiple copies
Approval: Test Copy
- Print a test copy of the flyer Will be submitted
Make any necessary revisions to the flyer
Print final version of the flyer, distribute or display the flyer to the target audience, track and assess the response and engagement of the flyer, take control of your workflows today., more templates like this.
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Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial
Affiliations.
- 1 Department of Internal Medicine 1 (Oncology, Hematology, Clinical Immunology, and Rheumatology), Saarland University Medical School, Homburg/Saar, Germany. Electronic address: [email protected].
- 2 Department of Internal Medicine 1, Westpfalz-Klinikum, Kaiserslautern, Germany. Electronic address: [email protected].
- 3 Institute for Medical Informatics, Statistics and Epidemiology, University Leipzig, Leipzig, Germany.
- 4 Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.
- 5 Department of Oncology, Oslo University Hospital, Oslo, Norway.
- 6 Department of Internal Medicine 1 (Oncology, Hematology, Clinical Immunology, and Rheumatology), Saarland University Medical School, Homburg/Saar, Germany.
- 7 Department of Hematology and Oncology, University Hospital of Cologne, Cologne, Germany.
- 8 Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
- 9 Department of Internal Medicine II, University Hospital Tuebingen, Tuebingen, Germany.
- 10 Department of Internal Medicine III, Klinikum Rechts der Isar der TU München, Munich, Germany.
- 11 Department of Medicine III, University Hospital, Munich, Germany.
- 12 Department of Hematology and Oncology, Georg August University of Goettingen, Goettingen, Germany.
- 13 Department of Internal Medicine I, Klinikum Mutterhaus der Borromaerinnen, Trier, Germany.
- 14 Department of Hematology and Oncology, University Medical Center, Freiburg, Germany.
- 15 Klinikum Fulda Tumorklinik, Fulda, Germany.
- 16 Department of Hematology and Oncology, Klinikum Oldenburg, Oldenburg, Germany.
- 17 Department of Internal Medicine II, University Hospital Eppendorf, Hamburg, Germany.
- 18 Department of Internal Medicine III, Dr Horst-Schmidt-Kliniken Wiesbaden, Wiesbaden, Germany.
- 19 Department of Internal Medicine III, Küchwald Hospital Chemnitz, Chemnitz, Germany.
- 20 Department of Hematology, Oncology and Immunology, University Hospital Marburg, Marburg, Germany.
- 21 Department of Internal Medicine II, City Hospital Kiel, Kiel, Germany.
- 22 Hematology Azienda Unità Sanitarie Locali-Istituto di Ricovero e Cura a Carattere Scientifico di Reggio Emilia, Reggio Emilia, Italy.
- 23 Hematology Azienda Socio Sanitaria Territoriale Spedali Civili Brescia, Brescia, Italy.
- 24 Department of Hematology, Rigshospitalet, Copenhagen, Denmark.
- 25 Dipartimento Chirurgico, Medico, Odontoiatrico e di Scienze Morfologiche con Interesse Trapiantologico, Oncologico e di Medicina Rigenerativa, University of Modena and Reggio Emilia, Modena, Italy.
- 26 Department of Internal Medicine III, University Hospital Mannheim, Mannheim, Germany.
- 27 Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
- 28 Department of Internal Medicine II, Evangelisches Diakonie-Krankenhaus, Bremen, Germany.
- 29 Institute of Pathology, University of Wuerzburg, and Comprehensive Cancer Center Mainfranken, Wuerzburg, Germany.
- 30 Department of Radiooncology, Saarland University Medical School, Homburg/Saar, Germany.
- 31 Department of Oncology, University Hospital of North Norway, Tromsø, Norway.
- 32 Department of Hematology, Rabin Medical Center, Beilinson Hospital, Petah-Tiqwa, Israel.
- 33 Department of Hematology, Oncology and Stem Cell Transplantation, Asklepios Klinik St Georg, Hamburg, Germany.
- PMID: 31868632
- DOI: 10.1016/S0140-6736(19)33008-9
Background: Six cycles of R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) are the standard treatment for aggressive B-cell non-Hodgkin lymphoma. In the FLYER trial, we assessed whether four cycles of CHOP plus six applications of rituximab are non-inferior to six cycles of R-CHOP in a population of patients with B-cell non-Hodgkin lymphoma with favourable prognosis.
Methods: This two-arm, open-label, international, multicentre, prospective, randomised phase 3 non-inferiority trial was done at 138 clinical sites in Denmark, Israel, Italy, Norway, and Germany. We enrolled patients aged 18-60 years, with stage I-II disease, normal serum lactate dehydrogenase concentration, ECOG performance status 0-1, and without bulky disease (maximal tumour diameter <7·5 cm). Randomisation was computer-based and done centrally in a 1:1 ratio using the Pocock minimisation algorithm after stratification for centres, stage (I vs II), and extralymphatic sites (no vs yes). Patients were assigned to receive either six cycles of R-CHOP or four cycles of R-CHOP plus two doses of rituximab. CHOP comprised cyclophosphamide (750 mg/m 2 ), doxorubicin (50 mg/m 2 ), and vincristine (1·4 mg/m 2 , with a maximum total dose of 2 mg), all administered intravenously on day 1, plus oral prednisone or prednisolone at the discretion of the investigator (100 mg) administered on days 1-5. Rituximab was given at a dose of 375 mg/m 2 of body surface area. Cycles were repeated every 21 days. No radiotherapy was planned except for testicular lymphoma treatment. The primary endpoint was progression-free survival after 3 years. The primary analysis was done in the intention-to-treat population. Safety was assessed in all patients who received at least one dose of assigned treatment. A non-inferiority margin of -5·5% was chosen. The trial, which is completed, was prospectively registered at ClinicalTrials.gov, NCT00278421 .
Findings: Between Dec 2, 2005, and Oct 7, 2016, 592 patients were enrolled, of whom 295 patients were randomly assigned to receive six cycles of R-CHOP and 297 were assigned to receive four cycles of R-CHOP plus two doses of rituximab. Four patients in the four-cycles group withdrew informed consent before the start of treatment, so 588 patients were included in the intention-to-treat analysis. After a median follow-up of 66 months (IQR 42-100), 3-year progression-free survival of patients who had four cycles of R-CHOP plus two doses of rituximab was 96% (95% CI 94-99), which was 3% better (lower limit of the one-sided 95% CI for the difference was 0%) than six cycles of R-CHOP, demonstrating the non-inferiority of the four-cycles regimen. 294 haematological and 1036 non-haematological adverse events were documented in the four-cycles group compared with 426 haematological and 1280 non-haematological adverse events in the six-cycles group. Two patients, both in the six-cycles group, died during study therapy.
Interpretation: In young patients with aggressive B-cell non-Hodgkin lymphoma and favourable prognosis, four cycles of R-CHOP is non-inferior to six cycles of R-CHOP, with relevant reduction of toxic effects. Thus, chemotherapy can be reduced without compromising outcomes in this population.
Funding: Deutsche Krebshilfe.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Publication types
- Clinical Trial, Phase III
- Comparative Study
- Equivalence Trial
- Multicenter Study
- Randomized Controlled Trial
- Research Support, Non-U.S. Gov't
- Administration, Intravenous
- Administration, Oral
- Antineoplastic Agents, Immunological / administration & dosage*
- Antineoplastic Agents, Immunological / therapeutic use
- Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
- Antineoplastic Combined Chemotherapy Protocols / therapeutic use
- Cyclophosphamide / administration & dosage
- Cyclophosphamide / therapeutic use
- Doxorubicin / administration & dosage
- Doxorubicin / therapeutic use
- Drug Administration Schedule
- International Cooperation
- Lymphoma, Large B-Cell, Diffuse / drug therapy*
- Lymphoma, Large B-Cell, Diffuse / pathology
- Middle Aged
- Neoplasm Staging
- Prednisone / administration & dosage
- Prednisone / therapeutic use
- Prospective Studies
- Rituximab / administration & dosage*
- Rituximab / therapeutic use
- Survival Analysis
- Treatment Outcome
- Vincristine / administration & dosage
- Vincristine / therapeutic use
- Young Adult
- Antineoplastic Agents, Immunological
- R-CHOP protocol
- Vincristine
- Doxorubicin
- Cyclophosphamide
Associated data
- ClinicalTrials.gov/NCT00278421
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Undergraduate Study Tours
The Sellinger School is offering three undergraduate study tours! You can travel abroad to China or Ireland, or domestically to Walt Disney World Resort in Orlando, FL. If you are interested in participating in one of these study tours, you must complete 3 steps:
1. Obtain clearance to travel from the Dean's office . You must complete the online approval form for international travel clearance and to indicate your study tour choice preference. A request for clearance must be submitted by the following dates:
- China: October 1
- Ireland: October 1 at 5 p.m.
- Disney: Approval for travel to Disney must be submitted at the Disney study tour site and is first come, first served
2. Make first nonrefundable payment of 50% of the trip price. Once you are cleared to travel, an e-mail will be sent to you with instructions for making your first payment. Your spot in a study tour is not reserved until this first payment is complete. First payment deadlines are:
- China: October 1 ($2,250 due at time of application))
- Ireland: October 13 at 5 p.m.
- Disney: Submitted within a few weeks of receiving travel clearance.
3. Make final payment . The final payments are due by:
- China: November 1 ($2,250)
- Ireland: November 3 at 5 p.m.
- Disney: The final payment for the Disney trip is due in the early fall
AC320.Z1 / FI426.Z1 - International Accounting/Finance Study Tour to China Jan. 3-12, 2020 Cost: $4,500
- Download the flyer and watch a video of a previous tour .
- Info sessions (SH318): Sept. 10 at 10 a.m. and Sept. 11 at 11 a.m.
- Contact Dr. Jalal Soroosh at [email protected] or x 2543 for additional information.
Online Approval Form
IS360.Z1 - Management of Global IT Study Tour to Ireland (Dublin and Cork) Feb. 28 - March 8, 2020 Cost: $2,600
- Download the flyer or visit the Ireland Study Tour website
- Info sessions (SH102): Friday, Sept. 6 from 2-2:45 p.m. and 3:15-4 p.m.
- Contact Dr. Paul Tallon at [email protected] or visit SH325 for additional information.
Walt Disney World Resort
MK349 - Customer Experience Management: The Disney Study Tour (Orlando, FL) Spring 2023 Cost: $1,975
- Visit the Disney Study Tour website
- Contact Dr. Rick Klink at [email protected] or x5546 for additional information
Registration Form (you will be sent to an external Disney Study Tour website)
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He missed a chance to be the first Black astronaut. Now, at 90, he's going into space
Scott Neuman
Ed Dwight poses for a portrait in February to promote the National Geographic documentary film The Space Race during the Winter Television Critics Association Press Tour in Pasadena, Calif. Chris Pizzello/Invision/AP hide caption
Ed Dwight poses for a portrait in February to promote the National Geographic documentary film The Space Race during the Winter Television Critics Association Press Tour in Pasadena, Calif.
Edward J. Dwight Jr. has waited a long time for his ride into space.
In the 1960s, he seemed poised to become America's first Black astronaut. That dream was never realized. Now, at age 90, he's about to finally get his shot, aboard a Blue Origin rocket.
The opportunity is "a curiosity more than anything else," Dwight says. "They called me up and asked me if I was interested. And of course I said yes."
The 1st Black Woman To Pilot A Spacecraft Says Seeing Earth Was The Best Part
While Dwight won't be the first African American in space — that honor went to Guion Bluford Jr. in 1983 — he will be the oldest person to go there, edging out (by a few months) Star Trek actor William Shatner , who flew aboard a Blue Origin rocket in 2021.
For many his age, a journey into space would seem unthinkable. Dwight says he's ready to go. He points out that the rigors of his upcoming flight won't be much different from what he experienced as a test pilot in the Air Force. "I've pulled more G's than any person on Earth," he says with a wry smile. "I've been high enough to see the curvature of the Earth. ... I've been doing things like that most of my life."
Space health expert Dorit Donoviel says the 11-minute flight of Blue Origin's New Shepard rocket means many of the concerns about the long-term effects of orbital and deep-space missions won't come into play.
"The main thing we worry about is the G forces," says Donoviel, director of the Translational Research Institute for Space Health at Baylor College of Medicine.
Air Force Capt. Edward J. Dwight Jr., the first African American selected as a potential astronaut, looks over a model of the Titan III-X-20 Dyna-Soar combination during a visit to Air Force headquarters in the capital in November 1963. Getty Images/Bettman Archive hide caption
Air Force Capt. Edward J. Dwight Jr., the first African American selected as a potential astronaut, looks over a model of the Titan III-X-20 Dyna-Soar combination during a visit to Air Force headquarters in the capital in November 1963.
Those G forces cause blood to drain from the head, and that's an issue for anyone launching into space, regardless of age. However, she points out that the seats aboard Blue Origin's rocket are angled at 20 or 30 degrees. "As you're experiencing the G-forces, you're getting it through the chest, which is not affecting your head," Donoviel says. "It's distributed through the chest, which really shouldn't matter very much."
And then there's the landing. The crew capsule will separate from the booster and come down under a set of parachutes — emitting a last-minute retro thrust to reduce speed to about 2 miles per hour to cushion the impact. "It's not even a controlled crash. It's a crash," Donoviel says. Still, she anticipates no issues.
No launch date set
Blue Origin has not announced a launch date yet. But Dwight and his crewmates will train for two days before liftoff at the company's Launch Site One in western Texas, not far from the Mexico border.
The company, owned by billionaire Jeff Bezos, declined to disclose the per-passenger cost of the flight, but says Dwight's seat is being sponsored by Space for Humanity and Blue Origin, with additional support from the Jaison and Jamie Robinson Family Foundation . (Jaison Robinson, who flew on a previous Blue Origin flight, is on the NPR Foundation Board of Trustees.)
Leland Melvin, a retired NASA astronaut who flew two space shuttle missions to the International Space Station, says it will be good to see Dwight finally "get his due" all these years after he first trained for space.
My Big Break
From touchdowns to takeoff: engineer-athlete soared to space.
Dwight sees his upcoming spaceflight as the "climax to an interesting story."
His own story, that is. One of the earliest chapters begins at an airfield in Kansas City, Kan. As a child, Dwight's fascination with aviation led to odd jobs cleaning aircraft owned by wealthy flyers. But even then, he had greater ambitions. "I told them I didn't want their nickels and dimes for cleaning airplanes anymore," he says. "I wanted to fly." At age 8, he got his first flight.
Dwight was equally interested in art and earned a scholarship to pursue his passion after high school. His father would have none of it. Art wasn't a real career, he insisted. Dwight should study engineering instead, so he enrolled at a junior college, receiving an associate's degree in 1953, the same year he enlisted in the Air Force.
After finishing primary flight training, he was commissioned as a second lieutenant. Dwight also got a bachelor's of science in aeronautical engineering from Arizona State University. Discrimination was an ever-present reality in the armed forces at the time, but as a skilled pilot, he made captain.
Kennedy wanted a Black astronaut
That's when President John F. Kennedy — eager to link his administration's push for civil rights to the country's early space exploration efforts — asked for a Black astronaut.
At the time, it was test pilots who became astronauts, and there were no Black test pilots. So, Dwight was invited to attend the Air Force's newly opened Aerospace Research Pilot School (ARPS).
But when he got the invitation letter, he almost threw it out, Dwight recalls. His Air Force peers "got a big laugh out of it," telling him that "all those guys have swagger, and it's a club," he said, referring to the all-white astronaut corps. They said, "They are not going to let you get in that club."
"And, of course, they were right," he says.
'Black In Space' Explores NASA's Small Steps And Giant Leaps Toward Equality
It was a huge career gamble. Dwight's father, who played baseball in the Negro Leagues, was strongly opposed. His mother, though, changed her son's mind. "She said, 'You are going to do this' because she was thinking it would be uplifting the race and racial pride," he says.
Upon entering the flight-test program, Dwight experienced immediate pushback that he says was rooted in racism. He says Chuck Yeager, the famed test pilot who ran the school, resented having to accept a Black candidate. (Yeager, who died in 2020, wrote in his memoir that his only issue was Dwight's piloting skills, which he described as "average.")
Once on the astronaut track, Dwight became a minor celebrity, especially in the Black community. He appeared on the cover of magazines such as Ebony and Jet . But he also endured taunts of "Kennedy's boy" because of the president's support.
Kennedy's 1963 assassination nearly derailed Dwight's training, he says. Days after the president's death, "Lo and behold, I had orders in my mailbox shipping me out of the country," he says.
Attorney General Robert F. Kennedy, the president's brother, intervened to keep him in the program, according to Dwight. He stayed in the Air Force for a few more years, but it became increasingly clear that he would not be selected as an astronaut. "When I found out it wasn't going to happen, that's when I left the program," he says. "I just packed my bags and left."
One of Ed Dwight's sculptures in Battle Creek, Mich., depicts escaped slaves along the Underground Railroad being led to freedom by Harriet Tubman and local abolitionist Erastus Hussey. Carlos Osorio/AP hide caption
One of Ed Dwight's sculptures in Battle Creek, Mich., depicts escaped slaves along the Underground Railroad being led to freedom by Harriet Tubman and local abolitionist Erastus Hussey.
After the Air Force, Dwight, who eventually settled in Denver, became a computer systems engineer for IBM, later opened a restaurant and worked as a real estate developer before being drawn back to his childhood love of art . Despite having little formal training, he was commissioned in 1974 to create a sculpture of Colorado's first Black lieutenant governor, George Brown.
Black History Month 2024
A child's dream to 'drive' a space shuttle propels him toward a historic nasa mission, from would-be astronaut to sculptor.
From there, his reputation as a sculptor blossomed. In 1977, he earned a master's of fine art in sculpture from the University of Denver. He specializes in sculpting historic African American figures. Among his more notable pieces are busts of jazz greats Dizzy Gillespie and one of Louis Armstrong on display at the National Museum of American History.
Melvin, who is African American, says when he met Dwight, he didn't know much about his backstory. "I got a copy of his book and I read some of the stuff that he had done," he says. "He reminded me of Katherine Johnson ," the NASA mathematician who led an all-woman group of "computers," who made vital orbital calculations for the agency's early crewed spaceflights. Their story was later featured in Hidden Figures, the book and 2016 film.
Dwight and Melvin became close friends. In recent months, they have worked together on The Space Race , a documentary released last year about the contributions and experiences of Black astronauts. Dwight's own story is prominent in the film.
NASA astronauts Victor Glover and Leland Melvin pose with Ed Dwight for a portrait to promote The Space Race in February at The Langham Huntington Hotel in Pasadena, Calif. Chris Pizzello/Invision/AP hide caption
NASA astronauts Victor Glover and Leland Melvin pose with Ed Dwight for a portrait to promote The Space Race in February at The Langham Huntington Hotel in Pasadena, Calif.
"He's not only funny, he's self-deprecating," Melvin says of Dwight. And one quality stands out. "He's got grit."
"But the other thing that his mother taught him was grace," he says. So, when being an astronaut didn't work all those years ago, "he gracefully pivoted to doing something else. It was just as impactful — just as impactful, especially in the Black community, which was his sculpture."
"He will now get his chance to do some zero-G floating and look at the planet from another vantage point," Melvin says.
Correction April 25, 2024
An earlier version of this story omitted Blue Origin as a sponsor of the flight that will take Edward J. Dwight Jr. into space.
- blue origin
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Edward J. Dwight Jr. is set to be on the next Blue Origin rocket into space. The rare opportunity comes more than six decades after he was passed over to become a NASA astronaut.
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