brazilian wandering spider food

Brazilian Wandering Spider: Care, Food, Habitat & Preventions

Mike Wallace

Have you ever heard of or do you know what a  Brazilian wandering spider is ? It is a big venomous spider from places like Central and South America, and people sometimes call it the  banana spider . Why? Well, we are about to find out!

Table of Contents

These wandering spiders are aggressive hunters who go out on the hunt at night. Their meals include both invertebrates (like insects) and vertebrates (creatures with a backbone, like small animals).

These spiders are super dangerous because their venom is like a powerful potion that can make people really sick or even worse. They usually hang out in tropical rainforests and even in cities, hiding in banana plants. 

So, let’s get more information about the world of this sneaky spider to learn the details about its looks, eating habits, where it lives, the venom it carries, and find out if it is genuinely risky. Ready to explore? Keep reading!

Brazilian Wandering Spider Description:

Scientific name and family:.

In Brazil, they are sometimes known as “ armed spiders ” (armadeiras), and they share the name “ banana spiders ” with a few other spiders. They have different names, but they are all talking about the same interesting spider!

The Brazilian wandering spider, scientifically known as  Phoneutria , Maximilian Perty kickstarted the Phoneutria genus in 1833. The name comes from the Greek word φονεύτρια , which means “murderess” and falls under the Animalia kingdom, Arthropoda phylum, and Arachnida class.

Within Arachnida, it is classified in the order Araneae, infraorder Araneomorphae, and Ctenidae family. The genus Phoneutria, described by Perty in 1833, includes the type species  Phoneutria fera .

This classification helps us understand where these spiders fit into the larger picture of living organisms.

The following 9 species are accepted by The  World Spider Catalog :

• Phoneutria bahiensis
• Phoneutria boliviensis
• Phoneutria eickstedtae
• Phoneutria fera
• Phoneutria keyserlingi
• Phoneutria nigriventer
• Phoneutria pertyi
• Phoneutria reidyi
• Phoneutria depilata

What do Brazilian Wandering Spider look like?

Size range:.

The spiders in the Phoneutria group can get pretty big in size. Their legs can stretch out to be 13 to 18 centimeters (5 to 7 inches) wide, and their bodies can have a range between 17 to 48 millimeters (a little more than half an inch to almost 2 inches) long.

The female Brazilian spiders can get pretty big, reaching up to 15 centimeters (5.9 inches) in length. On the other hand, the males are smaller, usually measuring around 7 centimeters (2.8 inches). They usually weigh up to 0.21 ounces.

They have long, slender legs, and even though some other spiders with different names might have longer legs, the Phoneutria spiders are champions when it comes to having the longest bodies and being the heaviest in their spider gang.

The spider’s body has two main parts. The first is the prosoma, kind of like its “head,” where you will find all eight legs, eyes, fangs (chelicera), and little multitasking arms (pedipalps).

The second part is the opisthosoma, holding the spinnerets for making silk, the back end opening (anal opening), “the lungs,” the heart, and the important bits for making baby spiders (reproductive organs).

So, the prosoma is like the front control center, and the opisthosoma is like the back office, handling things like silk-making and baby-making.

Brazilian spiders come in different colors, with most being hairy and shades of brown and gray. Some species may have lightly colored spots on their abdomen.

A distinctive feature of many species is the presence of bands of black and yellow or white on the underside of their two front legs.

Identification:

To identify a spider from the Phoneutria group, look for a dense brush of fine hairs on their leg parts. They might seem like other spiders, especially  Cupiennius , but here is how you can differentiate: 

• Phoneutria often have a dark line on the front of their palps and a thin black line on top of their head. 
• Check underneath, too; their legs usually have dark parts and light joints. Sometimes, the belly has black dots or is reddish. 
• Usually it has been observed that when they are upset, they do a cool defensive move like lifting their front legs high with a distinctive pattern. So, if you see a spider doing that dance, it is probably a Phoneutria!

Brazilian Wandering Spiders live all over the Americas, from Costa Rica to northern Argentina. They are like the residents of the jungle, chilling in forests east of the Andes in countries like Colombia, Venezuela, Ecuador, Peru, Bolivia, Brazil, Paraguay, and the Guianas.

Some, like P. reidyi, P. boliviensis, and P. fera, love the Amazon rainforest, while others prefer the Atlantic Forest in Argentina, Paraguay, and Brazil.

They have also made themselves at home in the Cerrado savanna. But if you head to northeastern Brazil, they are not around. These spiders have even taken trips to Chile and Uruguay.

Why are they called Banana Spiders?

These spiders are linked with bananas. Richard S. Vetter, a researcher at the University of California, found that these powerful spiders sometimes end up in North America and Europe by accident, hitching a ride in banana shipments.

But it is often a case of mistaken identity. Only a few Phoneutria species have been found in banana shipments, and sometimes, other spiders get the blame due to misidentification. 

What They Like to Eat or Hunt?

Their food includes flies, beetles, butterflies, moths, grasshoppers, locusts, and crickets. Occasionally, they might even feast on small creatures like amphibians, reptiles, or mice. All these diet or food findings tell us about how diversified eating habits these fascinating spiders have.

Mating and Lifecycle:

Like most spiders, the female spiders are bigger than the males. When the male spider wants to be friends, they do a little dance (vibrating his pedipalps and specialized sensory appendages) to signal his intentions to impress the female, but it is a cautious approach.

The behavior of the female can be choosy, and she might say no to a few before picking the right one. 

After the dance, sometimes, the females decide to attack them, or if she is interested, she can store the male’s baby-making material in a special place until she is ready to use it.

Then, she lays a bunch of eggs, up to 1,000 at a time, and keeps them safe in a silk egg sac. Sadly, after laying her eggs, the mom spider says goodbye. It is her way of making sure the new spiders are ready to explore the world on their own.

The lifespan of the banana spider (Phoneutria nigriventer) differs for males and females. Females usually live for 6 to 8 weeks after reaching maturity, while males have a shorter lifespan of 2 to 3 weeks after their last molt. 

Certain mammals, like coatis (Procyonidae, which includes raccoons) and other small insectivores, birds are potential predators of large wandering spiders.

These spiders got their name as wandering spiders because of the fact that they are not into web building. Instead, they stroll around the forest floor at night(nocturnal), searching for dinner.

Brazilian Wandering Spiders are active hunters and use both ambush tactics and direct attacks to catch their prey. During the day, they prefer cozy spots like under logs or in crevices, only emerging at night for their hunting adventures. These spiders do not build nests like other spider species.

While wandering spiders are not naturally aggressive towards humans, they won’t hesitate to bite if they feel cornered or threatened. Most bites happen when a spider accidentally gets trapped in clothing or bedding. 

Bite and Venom:

The bite of the armed spider is the most dangerous in the world as the venom it carries can be harmful to humans.

The danger is not just about how strong the venom is; it is also about factors like the spider’s likelihood to bite and how close it is to where people live.

These spiders often hide in houses, clothes, and other dark places during the day, making accidental bites more likely. 

While their fangs are adapted for small prey, some experts think they might give a “dry” bite in defense to save venom. Studies suggest that not all bites inject venom, and serious cases requiring antivenom are rare.

However, there have been confirmed cases of death, with symptoms appearing quickly, including:

• Severe pain
• Breathing difficulties
• Increased heart rate and blood pressure
• In severe cases, paralysis and death

The severity can depend on the spider’s sex, with females generally more dangerous. The spiders produce less venom in colder months, and a small amount can be potent enough to harm.

Fortunately, bites from Brazilian spiders are rare, and when they do occur, the exposure to the toxins is generally mild, as explained by Vetter.

Also Read: What is a Huntsman Spider? (Heteropodidae) – The Ultimate Guide

Banana Spider’s Facts:

Below are essential details about Brazilian wandering spiders:

• They hold the title for the world’s largest spiders , boasting leg spans reaching up to 15 centimeters (6 inches).
• Their venom packs a powerful punch, capable of inducing severe pain, paralysis, and, in extreme cases, fatal outcomes for humans.
• Despite their intimidating reputation, they are generally non-aggressive and resort to biting only when provoked.
• These spiders inhabit tropical rainforests and urban areas across Central and South America.
• In case someone has been bitten by this spider, he/she needs quick medical treatment to control the effects timely.

Treatment and Preventive Measures:

If bitten by a wandering spider or armed spiders, prompt medical attention is crucial. There is an antivenom for the spider’s venom, but its effectiveness is highest when administered within a few hours of the bite.

To prevent a bite:

• Wear protective clothing, use shoes and long pants when in areas where these spiders are found.
• Before wearing your clothes and shoes, make sure to check them to ensure no spiders are hiding.
• Maintain cleanliness and avoid leaving food or garbage exposed, as this can attract spiders.

These preventive measures are essential for minimizing the risk of encountering and getting bitten by Banana spiders.

Can Brazilian spiders kill humans?

Brazilian wandering spiders (Phoneutria nigriventer) are venomous and can potentially kill a human with a single bite. Their venom contains a potent neurotoxin that can cause severe pain, paralysis, and even death. 

Are Brazilian spiders poisonous?

Yes the venom of this spider is poisonous, that can cause death. While Brazilian wandering spiders are potentially dangerous, actual bites are relatively rare.

By adopting preventive measures and promptly seeking medical attention if bitten, the risk of serious complications can be significantly reduced.

Can you keep Brazilian spiders as pets?

It is strongly advised against keeping wandering spiders as pets due to their venomous nature and the potential risk to human safety.

Managing these spiders in captivity demands specialized knowledge and handling procedures to minimize the risk of bites.

Final Thoughts:

The Brazilian wandering spider, banana spider, or armed spider is a large and venomous arachnid found in Central and South America. While their potent venom can be harmful to humans, encounters are rare.

These nocturnal hunters have adopted various habitats, from rainforests to urban areas, and are associated with banana shipments. Understanding their appearance, behavior, and habitat is crucial for minimizing risks.

Seeking immediate medical attention after a bite is essential, as antivenom is available but most effective when administered promptly. Despite their fearsome reputation, the Brazilian spider remains a captivating and potentially dangerous species.

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Brazilian wandering spiders: Bites & other facts

The spider's name means "murderess" in Greek, which is appropriate for the deadly arachnid.

Classification/taxonomy

Size & characteristics, bites and venom, additional resources.

The Brazilian wandering spider, also called armed spiders or banana spiders, belongs to the genus Phoneutria , which means "murderess" in Greek. And it's no wonder why — it's one of the most venomous spiders on Earth . Its bite, which delivers neurotoxic venom, can be deadly to humans, especially children, although antivenom makes death unlikely.

Guinness World Records has previously named the Brazilian wandering spider the world's most venomous spider multiple times (though the current record-holder is the Sydney funnel-web spider, Atrax robustus , according to Guinness ). But, as the late Jo-Anne Sewlal, who was an arachnologist at the University of the West Indies in Trinidad and Tobago, told Live Science, "classifying an animal as deadly is controversial," as the amount of damage depends on the amount of venom injected. 

Jo-Anne Sewlal was a noted arachnologist from Trinidad and Tobago. While completing her PhD, she received the National Institute of Higher Education, Research, Science and Technology (NIHERST) 2012 Award for Excellence in Science and Technology for Junior Scientist. In 2013, She received a doctorate in zoology from the University of the West Indies. She discovered several species of spiders in her home country, surveyed the arachnids across several countries the Caribbean and appeared as an expert on the topic on The Science Channel. She died of an allergic reaction in January 2020.

There are nine species of Brazilian wandering spider, all of which are nocturnal and can be found in Brazil. Some species also can be found throughout Central and South America, from Costa Rica to Argentina, according to a 2008 article in the journal American Entomologist . Study author Richard S. Vetter, a research associate in the department of entomology at the University of California, Agriculture and Natural Resources, wrote that specimens of these powerful arachnids have been mistakenly exported to North America and Europe in banana shipments. However, Vetter noted, in many cases of cargo infestation, the spider in question is a harmless banana spider (genus Cupiennius ) that is misidentified as a Phoneutria . The two types of spiders look similar.

The taxonomy of Brazilian wandering spiders, according to the Integrated Taxonomic Information System (ITIS) , is:

Kingdom : Animalia Subkingdom : Bilateria Infrakingdom : Protostomia Superphylum : Ecdysozoa Phylum : Arthropoda Subphylum : Chelicerata Class : Arachnida Order : Araneae Family : Ctenidae Genus : Phoneutria  

• Phoneutria bahiensis
• Phoneutria boliviensis
• Phoneutria eickstedtae
• Phoneutria fera
• Phoneutria keyserlingi
• Phoneutria nigriventer
• Phoneutria pertyi
• Phoneutria reidyi
• Phoneutria depilata , according to a 2021 study published in the journal ZooKeys , which found that Phoneutria boliviensis actually included two separate species from different habitats. 

Brazilian wandering spiders are large, with bodies reaching up to 2 inches (5 centimeters) and a leg span of up to 7 inches (18 cm), according to the Natural History Museum in Karlsruhe, Germany. The species vary in color, though all are hairy and mostly brown and gray, although some species have lightly colored spots on their abdomen. Many species have bands of black and yellow or white on the underside of the two front legs, according to the University of Florida . 

These arachnids "are called wandering spiders because they do not build webs but wander on the forest floor at night, actively hunting prey," Sewlal told Live Science in an interview conducted in 2014, before her death. They kill by both ambush and direct attack.

They spend most of their day hiding under logs or in crevices, and come out to hunt at night. They eat insects, other spiders and sometimes, small amphibians, reptiles and mice. 

Research into one species of Brazilian wandering spider, Phoneutria boliviensis , revealed that these spiders eat a mix of arthropods and reptiles. DNA metabarcoding, a technique that examines the DNA and RNA in a sample, of the guts of 57 spiders identified 96 prey species, including flies, beetles, butterflies, moths, grasshoppers, locusts and crickets, according to research from the University of Tolima and the University of Ibagué in Colombia . Some of the female spiders also ate lizards and snakes.

While their bites are powerful and painful, "their bites are a means of self-defense and only done if they are provoked intentionally or by accident," Sewlal said.

In the Brazilian wandering spider, just as in most spider species, the female is larger than the male. Males approach females cautiously when attempting to mate, according to the biology department at the University of Wisconsin-La Crosse . Males perform a dance to get females' attention, and males often fight each other over the female. The female can be picky, and she often turns down many males before choosing a mating partner. Once she does pick one, the male needs to watch out; females often attack the males once copulation is finished.

The female then can store the sperm in a separate chamber from the eggs until she is ready to fertilize them. She will lay up to 1,000 eggs at a time, which are kept safe in a spun-silk egg sac.

Brazilian wandering spiders typically live for one or two years.

Brazilian wandering spiders' venom is a complex cocktail of toxins, proteins and peptides, according to the Natural History Museum in Karlsruhe, Germany. The venom affects ion channels and chemical receptors in victims' neuromuscular systems.

After a human is bitten by one of these spiders, he or she may experience initial symptoms such as severe burning pain at the site of the bite, sweating and goosebumps, Sewlal said. Within 30 minutes, symptoms become systemic and include high or low blood pressure , fast or a slow heart rate , nausea, abdominal cramping, hypothermia, vertigo, blurred vision, convulsions and excessive sweating associated with shock. People who are bitten by a Brazilian wandering spider should seek medical attention immediately.

Their  venom is perhaps most famous for triggering painful and long-lasting erections . For that reason, in a 2023 study, scientists reported that they were testing the venom in humans as a potential treatment for erectile dysfunction in those for whom Viagra didn't work.

However, these bites are rare, and envenomations, or exposure to these toxins from a spider bite, are usually mild, Vetter said. For instance, a 2000 study in the journal Revista do Instituto de Medicina Tropical de São Paulo found that only 2.3% of people with bites who came to a Brazilian hospital over a 13-year period were treated with antivenom. (The other bites did not contain enough venom to require it.) Most of the bites were from the species P. nigriventer and P. keyserlingi in eastern coastal Brazil. About 4,000 bites reportedly happen each year in Brazil, but only 0.5% of those cases are severe, according to a 2018 study in the journal Clinical Toxinology in Australia, Europe, and Americas . Meanwhile, 15 deaths have been attributed to Phoneutria in Brazil since 1903, the 2018 study reported. 

"It is unlikely that the spider would inject all of its venom into you, as this venom is not only needed as a means of defense but to immobilize prey," Sewlal said. "So if it did inject all of its venom, it [would] have to wait until its body manufactured more before it could hunt." That would also leave the spider vulnerable to being attacked by predators.

Furthermore, Sewlal pointed out that venom production requires a lot of a spider's resources and time. "So if the spider were to attack frequently and use up all of its venom, it [would] be safe to assume that it has a ready food supply to replace the energy and resources used. This situation does not exist in the wild."

• Learn more about Brazilian wandering spiders from the University of Wisconsin-La Crosse .
• Read about several species of Brazilian wandering spiders, including several images of the arachnids at the University of Florida .
• Find a spider in your bananas? It may or may not be a deadly species, according to the University of California, Riverside .

This article was originally published on Nov. 20, 2014. 

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Jessie Szalay is a contributing writer to FSR Magazine. Prior to writing for Live Science, she was an editor at Living Social. She holds an MFA in nonfiction writing from George Mason University and a bachelor's degree in sociology from Kenyon College. 

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Brazilian Wandering Spider

The Brazilian Wandering Spider (Phoneutria fera) is an aggressive and highly venomous spider . It was first discovered in Brazil hence its name. However, this genus is known to exist elsewhere in South and Central America .

The Brazilian Wandering spider is a member of the Ctenidae family of wandering spiders.

The Brazilian Wandering spider appeared in the Guinness Book of World Records 2007 for being the most venomous animal .

In this particular genus, there are five known similar species whose members are also highly venomous. They include some of the relatively few species of spiders that present a threat to human beings.

Brazilian Wandering Spider Characteristics

The Brazilian wandering spider can grow to have a leg span of up to 4 – 5 inches. They are large hairy spindly-looking spiders who have eight eyes, two of which are large. Brazilian wandering spiders are fast-moving spiders, their legs are strong and spiny and they have distinctive red jaws which they display when angered.

The Brazilian wandering spider is not a Tarantula . Brazilian wandering spiders are not even in the same family group. Tarantulas are harmless to humans and are mostly ambush killers who wait for prey to come to them. Brazilian wandering spiders are active hunters. Brazilian wandering spiders and Tarantulas do have one thing in common, however, they do not eat bananas.

Brazilian Wandering Spider Habitat and Spider Webs

The Brazilian Wandering spider is so-called because it wanders the jungle floor, rather than residing in a lair or maintaining a web. This is another reason it is considered so dangerous. In densely populated areas, the Brazilian Wandering spider will usually search for cover and dark places to hide during daytime, leading it to hide within houses, clothes, cars, boots, boxes and log piles. This usually causes accidents when people disturb them.

The Brazilian Wandering spider is also called the ‘banana spider’ as it is occasionally found within shipments of bananas. As a result, any large spider appearing in a bunch of bananas should be treated with due care.

Brazilian Wandering Spider Diet

Adult Brazilian Wandering spiders eat crickets, other large insects, small lizards and mice. Spiderlings of this species eat flightless fruit flies and pinhead crickets.

Brazilian Wandering Spider Reproduction

All spiders produce silk, a thin, strong protein strand extruded by the spider from spinnerets most commonly found on the end of the abdomen. Many species use it to trap insects in webs, although there are many species that hunt freely such as the Brazilian Wandering spider. Silk can be used to aid in climbing, form smooth walls for burrows, build egg sacs, wrap prey and temporarily hold sperm, among other applications.

Brazilian Wandering spiders reproduce by means of eggs, which are packed into silk bundles called egg sacs. The male spider must (in most cases) make a timely departure after mating to escape before the females normal predatory instincts return.

Mature male spiders have swollen bulbs on the end of their palps for this purpose and this is a useful way to identify whether the spider is male or female. Once the sperm is inside the female spider, she stores it in a chamber and only uses it during the egg-laying process, when the eggs come into contact with the male sperm for the first time and are fertilized. The Brazilian Wandering spiders life cycle is 1 – 2 years.

Brazilian Wandering Spider Venom

Bites from the Brazilian Wandering spider may result in only a couple of painful pinpricks to full-blown envenomed. In either case, people bitten by this spider or any Ctenid should seek immediate emergency treatment as the venom is possibly life threatening.

The Phoneutria fera and Phoneutria nigriventer (two species of wandering spider) are the two most commonly implicated as the most vicious and deadly of the Phoneutria spiders.

The Phoneutria not only has a potent neurotoxin, but is reported to have one of the most excruciatingly painful envenoms of all spiders due to its high concentration of serotonin. They have the most active venom of any living spiders.

One of their members, the Brazilian Huntsman, is thought to be the most venomous spider in the world. Brazilian wandering spiders are certainly dangerous and bite more people than any other spiders.

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Brazilian Wandering Spider Facts

Brazilian wandering spider profile.

There are more than 50,000 species of spider, and the vast majority are less dangerous than a honeybee. Almost none are aggressive, and of those with medically significant venom, only a small percentage are capable of causing death. So, on the whole, arachnophobes are just being a bit silly.

But there’s one spider that vindicates all of these fears, and few animals are as globally renowned to be a serious threat to human lives as the Brazilian Wandering Spider .

Brazilian Wandering Spiders are actually 9 species of spider in the same genus ‘Phoneutria’, one of which is found in Central America, with the rest in South America.

Brazilian Wandering Spider Facts Overview

These spiders are called wandering spiders because of instead of spinning a web to wait for food, or occupying a lair, they spend their night wandering in the leaf litter of the jungle floor for prey.

The sensitive hairs on its body help detect vibrations of passing prey, and it will feed on insects, lizards, frogs and any animals as large as itself.

During the day they will hide under logs, rocks, or inside termite mounds and banana plants. They will also sometimes wander into urban areas and homes, where they can come into contact with humans.

Brazilian wandering spiders are aggressive , dangerous and frightening. For once, this is an animal you should be wary of.

The females are larger, around 50% heavier than males, and produce more venom, and this might be a clue as to why their Greek name translates to “ Mudress” . These spiders will often stand and fight and have an intimidating threat display.

The potency of their venom is one of the reasons they’re so dangerous, and their ability to hide away in fruit and shoes explains why most bites are on extremities.

Interesting Brazilian Wandering Spider Facts

1. armed spiders.

In Brazilian, these are sometimes known as armed spiders, on account of their elongated front legs.

They can convey quite a bit of information with these legs, and as wandering spiders, use them to get about the forest, looking for food.

2. Banana Spiders

They’re also sometimes called ‘banana spiders’ on account of their status as a stowaway on popular fruit imported from the tropics.

This is becoming less common as stricter regulations ensure there’s less contamination of fruits, but there’s always a chance your next bunch of bananas will have a family of these spiders living inside it.

3. They have the largest venom glands of any spider

Females produce more venom than males, but both sexes have enormous venom glands. These glands are even more impressive when you consider the size of the spider is significantly less than the largest around.

The venom glands of the Brazilian Wandering Spider are over a centimetre long, and this is all housed inside the bright red chelicerae (mouth parts) which they are quick to display whenever they get upset. 1

4. They’re aggressive

These spiders can grow quite large and have long, brightly-coloured legs. Unlike most spiders, they’re known to stand their ground when threatened and are far quicker to bite than many other species.

They’ll still try to scurry away where possible, and they’re not out to get anybody.

But where most other species will flee, the wandering spiders’ aggression does make it more likely to be involved in incidents.

Most bites are on fingers and toes, a sign that they’re being stepped on or grabbed inadvertently. When the spider feels cornered, it’ll rear up on its back legs and waves its colourful arms around as a warning.

Then it’ll sway side to side, beckoning you to have a go. Anything foolhardy enough to call this bluff gets a wealth of envenomation effects. 2 3

5. They give some men erections

There are ways to accomplish this with fewer side effects, but a bit from a Brazilian wandering spider does come with a certain Viagral quality.

This isn’t as fun as it might sound. Prolonged erections in this manner are likely to harm and destroy muscles and blood vessels in the penis and could cause irreparable damage.

Besides this, the assault on the central nervous system that comes with envenomation by this spider doesn’t sound worth it. 4

6. And some people die

This assault brings with it a whole host of unpleasant symptoms. Seizures, foaming at the mouth, inability to speak, collapse, and a host of other miserable experiences.

Paralysis is possible, as is cardiac shock. Blood vessels can burst in the brain, or anywhere else, and in many cases, this can be enough to kill a person.

This spider has one of the most potent venoms of all, and there are multiple legitimate records of death as a result of bites.

7. But they’re rarely fatal

While the Brazilian wandering spider is potentially one of the most dangerous spiders in the world, there is some evidence to suggest it gives a dry bite, defensively.

This means that despite exceptionally toxic venom, the amount actually injected is less than some of the other contenders, and this is what makes it typically less lethal than the Australian funnel webs.

These spiders are classified as Dangerous Wild Animals and would therefore require a special permit to keep. Bites from wandering spiders are common in South America, but antivenom is often readily available, and they rarely result in death.

In most cases, lethal bites are cases of a very young or very old victim, and few people of healthy age are killed. 5

8. They do invade the UK sometimes

These unquestionably scary spiders show up in supermarkets in the UK on occasion, having hitched a ride on banana shipments.

On more than one occasion they’ve made their way into shoppers’ homes, but it doesn’t appear that there are any cases of them biting people as a result.

These spiders aren’t suited for temperate climates and don’t survive Winter, so there’s no risk of them multiplying.

Brazilian Wandering Spider Fact-File Summary

Scientific classification, fact sources & references.

• PeerJ. (2017), “ Dimensions of venom gland of largest venom glands in all spiders ”, Bio Numbers.
• Dave Clarke (2010), “ Venomous spider found in Waitrose shopping ‘beautiful but aggressive’” , The Guardian.
• “ Phoneutria Perty (Arachnida: Araneae: Ctenidae) ”, UF-IFAS University of Florida
• Kátia R.M. Leite (2012), “ Phoneutria nigriventer spider toxin Tx2-6 causes priapism and death: A histopathological investigation in mice ”, Science Direct.
• “ Brazilian wandering spiders: Bites & other facts ”, Live Science.

Wellcome to SpiderZoon

• Spider Facts

Brazilian Wandering Spider: Size, Bite, Diet and Other Facts 

The Brazilian Wandering Spider is a venomous arachnid with a fearsome reputation. This South American rainforest dweller packs a powerful punch, but don’t let its nickname “banana spider” fool you – they’re active hunters, not web-spinners. Despite their size and venom, bites are uncommon as they’re typically shy.

The Brazilian Wandering Spider has garnered significant attention due to its potent venom, which makes it one of the world’s most venomous spiders. Understanding its biology and behavior is crucial for both scientific research and public safety.

Table of Contents

Scientific classification

The Brazilian Wandering Spider belongs to the family Ctenidae within the order Araneae. Its scientific classification is as follows:

• Kingdom: Animalia
• Phylum: Arthropoda
• Class: Arachnida
• Order: Araneae
• Family: Ctenidae
• Genus: Phoneutria

The Brazilian Wandering Spider goes by various common names, including “armed spider,” “banana spider,” and “wandering spider.” Synonyms for this species may include Ctenus , which was formerly used for some Phoneutria species.

Distribution and habitat

Distribution:

• South American:  Found throughout most of South America east of the Andes mountains, including countries like Brazil (their namesake), Argentina, Paraguay, and up into northern regions.
• Central American Touch:  A few species even reach southern Central America.
• Rainforest Dwellers:  Primarily found in the lush rainforests of South America.
• Not Picky Places:  They can also adapt to other habitats like the Atlantic Forest and even some urban areas.
• Daytime Hideouts:  While they wander at night, they seek shelter during the day in places like termite mounds, under rocks, or even (unintentionally) in bananas!

Physical Characteristics

 size and weight.

The Brazilian wandering spider is a creepy crawly giant. Their bodies can grow up to 2 inches (5 centimeters) long, but that’s not the scary part. Their legs can span a whopping 7 inches (18 cm), making them look even bigger. They are one of the biggest true spiders by body weight and size.

Despite their impressive leg span, Brazilian wandering spiders are relatively light. They only weigh around 6 grams, which is about the same as two pennies. While they might look imposing, they’re not the heaviest arachnids around.

Coloration and markings

These spiders exhibit a range of colors, including brown, black, and sometimes reddish hues. They often have distinctive markings on their bodies, which can vary between species. These markings may include stripes or patterns that serve as a key identification feature.

Notable features

One of the most notable features of the Brazilian Wandering Spider is its elongated, robust body and long, agile legs. They have sharp fangs, which they use to inject venom into their prey or in self-defense.

Sexual dimorphism

Sexual dimorphism is evident in this species. Females are larger and bulkier than males, while males have longer, more slender legs. Additionally, males possess specialized structures known as pedipalps, which are used during mating.

In the following sections of this article, we will delve deeper into the behavior, venom, and ecological role of the Brazilian Wandering Spider, shedding light on why this species has both fascinated and instilled fear in those who encounter it.

 Behavior and Ecology

 Nocturnal habits

Brazilian Wandering Spiders are primarily nocturnal creatures. They are most active during the night, venturing out of their daytime hiding places to hunt for prey and engage in mating activities. Their nighttime activity allows them to avoid predators and reduce the risk of desiccation in the hot tropical sun.

Hunting and feeding behavior

These spiders are agile hunters and primarily feed on insects, small vertebrates, and other arachnids. They do not build webs to capture prey but instead rely on their excellent senses, including acute vision and touch, to locate and stalk their victims. They often wander in search of food and are known for their swift and lethal strikes. Once they subdue their prey, they inject venom to immobilize it before feeding.

Brazilian Wandering Spiders (Phoneutria) are active hunters and have distinctive feeding behaviors. Here’s an overview of their feeding habits:

• Active Predators: Brazilian Wandering Spiders are not web-builders like many other spider species. Instead, they are active predators. They actively roam their environment in search of prey rather than waiting for insects to stumble into a web.
• Hunting Strategy: When hunting, these spiders use their excellent senses, including acute vision and touch, to locate potential prey. They are known for their agility and speed, which they use to stalk and capture their victims. They have sharp fangs, which they use to deliver a venomous bite to immobilize their prey.
• Diet: Their diet consists primarily of insects and other arthropods, but they are opportunistic feeders and may consume a variety of small creatures, including small vertebrates such as frogs and lizards when the opportunity arises.
• Venom Use: Brazilian Wandering Spiders inject venom into their prey to immobilize and partially digest it. Their venom contains neurotoxins that affect the nervous system of their victims. Once the prey is incapacitated, the spider can feed on it at its leisure.
• Feeding Process: After subduing their prey with a venomous bite, the spider uses its chelicerae (fangs) to break down the prey’s tissues. The venom also helps in predigestion, turning the prey’s insides into a semi-liquid form that the spider can ingest. They can consume both the internal fluids and solid parts of their prey.
• Frequency of Feeding: The frequency of feeding can vary depending on factors such as the availability of prey and the spider’s size. Generally, they need to feed periodically to sustain their energy and growth. Spiderlings may require more frequent meals to support their rapid growth, while adults can go longer periods between meals.

Overall, the Brazilian Wandering Spider’s feeding strategy is well-suited for their active and wandering lifestyle, allowing them to efficiently capture and consume a variety of prey in their natural habitat.

Role in the ecosystem

The Brazilian Wandering Spider plays a vital role in controlling insect populations within its habitat. By preying on a variety of insects and other small creatures, they help maintain ecological balance. Additionally, their presence in the rainforest ecosystem contributes to the overall biodiversity and food web.

Mating and reproduction

Mating in Brazilian Wandering Spiders is a complex and potentially dangerous process. Male spiders must carefully approach and court a receptive female to avoid being mistaken for prey. They use specialized pedipalps to transfer sperm to the female’s reproductive organs. After successful mating, females lay egg sacs containing hundreds of eggs. They guard these sacs and ensure the survival of their offspring until they hatch.

 Lifespan and growth

The lifespan of Brazilian Wandering Spiders varies between males and females. Males generally have a shorter lifespan, typically living for a few months to a year after reaching maturity. Females, on the other hand, can live for several years. The growth of these spiders involves a series of molts, during which they shed their exoskeletons to accommodate their increasing size. Molting is a vulnerable period in their lives as their new exoskeleton is initially soft and requires time to harden.

Venom and Envenomation

Composition of venom.

The venom of Brazilian Wandering Spiders is a complex mixture of neurotoxins, cytotoxins, and other enzymes. One of the most significant components is a neurotoxin called PhTx3, which targets the nervous system of their prey.

Toxicity and effects on humans

The venom of these spiders is highly potent and can be lethal to their prey. In humans, envenomation can cause a range of symptoms, including intense pain, muscle cramps, fever, nausea, and in severe cases, paralysis and death. It’s important to note that while their venom is potent, actual fatalities from Brazilian Wandering Spider bites are rare due to the availability of medical treatment.

First aid and medical treatment

In the event of a Brazilian Wandering Spider bite, immediate medical attention is crucial. First aid measures may include cleaning the wound and applying ice to reduce pain and swelling. However, the primary treatment involves antivenom, which can counteract the effects of the spider’s venom.

Cases of envenomation and fatalities

Although fatalities from Brazilian Wandering Spider bites are uncommon, there have been documented cases of severe envenomation, especially in regions where medical treatment is not readily available. These spiders are generally non-aggressive and will bite humans only in self-defense when provoked, or if they feel cornered.

Understanding the behavior, ecology, and venomous nature of the Brazilian Wandering Spider is crucial for both scientific research and public awareness, helping to minimize the risk of envenomation and promote coexistence with this remarkable but potentially dangerous arachnid.

Brazilian wandering spider life cycle

The Brazilian wandering spider has a fascinating life cycle that revolves around hunting and motherhood. Here’s a breakdown:

• Egg Haven:  After mating, the female lays hundreds, sometimes even a thousand, eggs in a silken sac. This becomes their protected nursery.
• Tiny Terrors:  Hatching from the eggs emerge translucent spiderlings called larvae.
• Nymph Stage:  The larvae molt a few times, transforming into nymphs. Think of them as mini-adults but without the ability to reproduce yet.
• Shedding for Size:  As nymphs grow, they undergo multiple molts, shedding their outer shell to accommodate their larger bodies.
• Ready to Roam:  After the final molt, the spider emerges as a full-fledged adult, complete with reproductive organs. Now, they can join the wandering lifestyle and continue the cycle.

The life cycle begins when a female Brazilian Wandering Spider lays her eggs. She typically creates an egg sac made of silk and deposits it in a concealed location, such as a tree hollow or leaf litter. Inside the sac, she may lay hundreds of eggs. The female guards the egg sac and ensures its protection until the spiderlings hatch. The duration of the egg stage varies depending on environmental conditions but generally lasts for a few weeks.

Spiderling Stage

After the incubation period, spiderlings (young spiders) emerge from the egg sac. They are extremely vulnerable at this stage and rely on their mother’s protection and guidance. Spiderlings are miniature versions of adult spiders but lack the full coloration and size. They disperse from the nest once they have molted and are capable of hunting on their own. During this stage, they grow rapidly by molting, shedding their exoskeletons to accommodate their increasing size.

Juvenile Stage

As spiderlings continue to molt and grow, they progress into the juvenile stage. During this phase, their coloration becomes more distinct, and they start to develop the characteristic features of adult Brazilian Wandering Spiders. They become increasingly independent and begin to exhibit hunting behaviors. The duration of the juvenile stage can vary but often lasts several months.

Sub-Adult Stage

The sub-adult stage is an intermediate phase between juvenile and adult. At this point, the spiders are closer in size and appearance to adults but have not yet reached sexual maturity. They continue to molt, with the frequency of molting gradually decreasing as they approach adulthood. Sub-adult spiders may exhibit more territorial behaviors as they compete for resources and prepare for eventual mating.

Adult Stage

Upon reaching sexual maturity, Brazilian Wandering Spiders enter the adult stage. This is when they are fully developed and capable of reproduction. Females are larger and bulkier than males, and males possess specialized structures called pedipalps, which they use during mating. Adult spiders engage in mating activities, and females lay eggs to continue the life cycle. Adult Brazilian Wandering Spiders can live for several years, with females typically having longer lifespans than males.

Understanding the life cycle of these spiders is essential for studying their behavior, reproductive biology, and population dynamics. It also provides insights into their adaptation strategies in the complex ecosystems of South and Central America.

Brazilian Wandering Spider Bite

Brazilian Wandering Spiders are known for their potent venom and, occasionally, their bites on humans. While bites are relatively rare due to the spider’s non-aggressive nature, understanding the consequences of a bite is crucial for public safety.

Studying Brazilian Wandering Spider bites is of great interest for several reasons. It helps healthcare professionals provide appropriate medical treatment, raises awareness among communities in spider habitats, and contributes to our understanding of venomous arachnid envenomations.

The venom of Brazilian Wandering Spiders is a complex mixture of neurotoxins, cytotoxins, and enzymes. It contains various components, including PhTx3, which is a potent neurotoxin affecting the nervous system.

Brazilian Wandering Spider bites can have a range of effects on the human body, including intense pain, muscle cramps, fever, nausea, and in severe cases, paralysis. The severity of the symptoms depends on factors such as the amount of venom injected and the individual’s sensitivity to the venom. There are several types of spider bites .

Symptoms of a Brazilian Wandering Spider Bite

Local symptoms

• Intense pain
• Itching or burning sensation
• Formation of blisters or lesions

Systemic symptoms

• Muscle cramps and spasms
• Abdominal pain
• Nausea and vomiting
• Elevated heart rate
• Hypertension (high blood pressure)
• Respiratory distress

Severity and variations

The severity of Brazilian Wandering Spider bite symptoms can vary widely. In some cases, symptoms may be mild and resolve on their own, while in severe envenomations, life-threatening complications can occur. Individual reactions to the venom can also vary, making it challenging to predict the exact outcome of a bite.

First Aid and Immediate Response

Steps to take after a bite

Immediate response to a Brazilian Wandering Spider bite should include:

• – Washing the bite area with soap and water.
• – Applying a clean, cool compress to reduce pain and swelling.
• – Immobilizing the affected limb or area.
• – Keeping the bite victim calm to prevent an elevated heart rate.

Do’s and don’ts in case of a bite

• – Seek medical attention promptly.
• – Take note of the spider’s appearance (if possible) to aid identification.
• – Keep the bite victim still and calm to reduce the spread of venom.
• – Do not try to suck out venom or make incisions at the bite site.
• – Avoid applying tourniquets.
• – Don’t use ice directly on the skin as it can worsen tissue damage.

Seeking medical attention

Medical attention is essential after a Brazilian Wandering Spider bite, even if symptoms appear mild initially. Antivenom is available and can be administered to counteract the effects of the venom. Medical professionals can also manage symptoms and monitor for potential complications.

Complications and Long-Term Effects

Potential complications

Complications from Brazilian Wandering Spider bites can include:

• – Severe muscle spasms
• – Respiratory distress
• – Cardiovascular issues
• – Kidney failure (rare)
• – Allergic reactions to antivenom

Long-term consequences

Long-term consequences of a bite can vary depending on the severity and medical treatment received. Some individuals may experience lingering pain, muscle weakness, or psychological trauma following a severe envenomation.

Recovery and rehabilitation

Recovery from a Brazilian Wandering Spider bite typically involves medical treatment, rehabilitation for muscle and nerve damage, and psychological support for individuals affected by the experience. Rehabilitation may include physical therapy to regain muscle strength and function. Prompt medical attention and appropriate care are crucial for minimizing long-term effects and complications.

Facts of Brazilian Wanding Spider

Here are 10 creepy crawly facts about the Brazilian Wandering Spider:

• Big and Hairy:  These spiders are giants! Their bodies can grow up to 2 inches (5 centimeters) long, with a leg span of up to 7 inches (18 cm). They are covered in hairs, making them appear even bigger.
• Wanderlust:  They are aptly named – Brazilian wandering spiders don’t spin webs. Instead, they wander the forest floor at night in search of prey.
• Venomous Bite:  Their venom is considered one of the most potent among spiders. A bite can cause severe pain, swelling, sweating, nausea, and even priapism in males. Thankfully, bites are rare as they are typically shy and defensive.
• Not So Fond of Bananas:  While sometimes called ‘banana spiders,’ they are not typically found in bananas. They might, however, take shelter in them during transport, which is how they might end up in a faraway land.
• Rainforest Resident:  These spiders are native to the rainforests of South America, particularly in Brazil.
• Fearsome Feasters:  They’re active hunters and will eat almost anything they can overpower, including insects, lizards, frogs, and even small rodents.
• Mom’s the Word:  Female Brazilian wandering spiders are dedicated mothers. They lay hundreds of eggs in a silken sac and fiercely guard them until they hatch.
• Multiple Molts:  Like all spiders, Brazilian wandering spiders grow through molting. They shed their exoskeleton multiple times as they grow into adults.
• Mating Dance:  Male Brazilian wandering spiders perform a elaborate mating dance to attract a female.
• Medicinal Potential:  Despite their scary reputation, the venom of the Brazilian wandering spider is being studied for its potential use in treating erectile dysfunction.

What happens if a Brazilian Wandering Spider bites a man?

A Brazilian Wandering Spider bite on a man can cause a range of symptoms, some severe:

• Pain:  The bite is known for causing intense, localized pain at the site.
• Autonomic effects:  Sweating, nausea, and increased heart rate are common.
• Priapism:  In some cases, males may experience a prolonged and painful erection (priapism). This is due to a component in the venom.
• Muscle paralysis:  Severe bites can lead to muscle paralysis, which can affect breathing in rare cases.

However, it’s important to remember:

• Bites are uncommon as these spiders are typically shy and defensive.
• Antivenom is available and effective in treating bites.

If bitten, seek medical attention immediately. Early treatment can help prevent complications and ensure a full recovery.

How poisonous is a Brazilian Wandering Spider?

Brazilian Wandering Spider packs a nasty venomous punch, considered one of the strongest among spiders. Bites are rare though, as they’re shy and prefer to escape trouble.

What is the world’s deadliest spider?

The term “deadliest” can be subjective and depends on how one defines it (e.g., based on venom potency or human fatalities). However, the Brazilian Wandering Spider (Phoneutria) is often considered one of the most venomous spiders in the world. Another spider often mentioned in discussions of venom toxicity is the Sydney Funnel-web Spider (Atrax robustus and Atrax formosus), found in Australia. These spiders are known for their potent venom and have caused fatalities in the past.

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What Do Brazilian Wandering Spiders Eat?

Brazilian Wandering Spiders are carnivorous arthropods that primarily consume other small invertebrates and occasionally small vertebrates.

• Insects : These spiders prey on various insects like beetles, grasshoppers, and other small bugs.
• Arachnids : They often consume other spiders and scorpions.
• Small vertebrates : Occasionally, they hunt small lizards, frogs, and mice.
• Amphibians : Small frogs are also part of their diet.
• Crickets : These are a common food source in their natural habitat.
• Caterpillars : They prey on caterpillars, especially those found on the forest floor.
• Small birds : Rarely, they can prey on small, nestling birds.

How do Brazilian Wandering Spiders Eat?

Brazilian Wandering Spiders are active hunters that use venom to paralyze their prey before consuming it.

• They seek out and stalk their prey, primarily insects and small vertebrates.
• Once they locate a target, they inject it with venom, paralyzing or killing the prey.
• After the prey is immobilized, the spider uses its chelicerae (jaws) to crush and ingest the prey.
• The spider's digestive system liquefies the prey's internal tissue, which is then sucked up by the spider.

What do Brazilian Wandering Spiders Drink?

Brazilian Wandering Spiders, also known as Phoneutria, are large, venomous spiders native to tropical South America. They are primarily carnivorous but also consume fluids for hydration.

• Water : The primary fluid intake for hydration.
• Body Fluids of Prey : They consume body fluids of their prey, which include small insects and sometimes small amphibians or reptiles.

FAQs about Brazilian Wandering Spiders

1. how often do brazilian wandering spiders eat.

Brazilian Wandering Spiders typically eat once or twice a week, depending on the size and availability of their prey.

2. How long can a Brazilian Wandering Spiders live without eating?

A Brazilian Wandering Spider can survive without eating for up to a month, as they have a slow metabolic rate.

3. What do Larvae Brazilian Wandering Spiders eat?

Larvae Brazilian Wandering Spiders do not eat; they are dependent on the yolk sac from their eggs until they mature into spiderlings.

Do Brazilian Wandering Spiders Bite?

Check information about Brazilian Wandering Spiders and learn if they bite or not and what you should do in case they bite.

Brazilian Wandering Spider Profile

Check the profile of and learn more interesting information about them.

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Brazilian Wandering (Phoneutria)

The Brazilian Wandering spider is a type of spider from the Phoneutria group. Even though they’re called “Brazilian,” not all of them come from Brazil. They’re known for having strong venom. In this post, we’ll share cool facts about these spiders and help you understand them better.

Scientific Classification

• Family: Ctenidae
• Genus: Phoneutria

List of Spiders Belonging to This Genus

Physical description and identification.

• Size: They are large in size, with their body being 17- 48mm (.67 – 1.89 inches) long and they also have a leg span of 130 – 150 mm (5.1-5.9 inches).
• Color: The color may vary from one species to the other, though most of them have a brown hairy body, with black spots on their stomach. Some have bright, red hairs on their mouthparts or chelicerae, while others may lack it, a feature that confuses them with species of another genus, particularly the Cupiennius.
• Other characteristics: They often lift their body in an erect posture and hold their frontal legs high to defend themselves against predators.

They are safely placed in a silken sac and the female spiders of this genus are known to lay about 1000 of them in her lifetime.

Spiderlings

They remain with their mother for some time after which they disperse to be on their own. The juvenile spiders are known to consume pin crickets as well as non-volatile fruit flies for their diet.

The spiders of this genus do not build webs but walk on the jungle floor, on the lookout for their prey.

Are Brazilian Wandering Spiders Venomous?

Yes, Brazilian Wandering Spiders have strong venom. They use it to catch their food. It’s one of the reasons they’re pretty famous.

Can Brazilian Wandering Spiders Bite?

Yes, they can bite. While they don’t always want to, they might if they feel scared or threatened by something.

How Fast Can a Brazilian Wandering Spider Kill One?

It has been reported that the bite of species belonging to this genus may result in the victim’s death within one hour after the venom enters the person’s body. However, with effective anti-venom being introduced for treatment in Brazil to combat the toxic effects of these spiders, the incidence of fatalities has been less. In fact, most studies show that death mostly occurs in children below seven years of age. Of all the eight species, P. nigriventer , followed by P. fera, is said to account for most venom intoxications in Brazil.

Ecological Importance and Behavior of the Brazilian Wandering Spider

The Brazilian Wandering Spider, scientifically known as Phoneutria, stands out not just because of its reputation as one of the world’s most venomous spiders , but also due to its ecological significance and unique behavior.

Natural Predator: Despite their fearsome reputation, Brazilian Wandering Spiders are not at the top of the food chain. They fall prey to larger animals and birds. Among their predators are the coatis, certain species of large spiders, and a variety of avian predators.

Prey-Predator Dynamics: The dynamic between the Brazilian Wandering Spider and its prey is a showcase of nature’s balance. While they are efficient hunters, specializing in ambushing their prey, their own survival is constantly under threat from their predators. This cycle ensures that no one species dominates the ecosystem and that biodiversity thrives.

Relationship with Humans: The relationship between humans and the Brazilian Wandering Spider is one of respect and caution. Their venom is potent and can be harmful to humans, although fatal encounters are rare. 

Quick Facts

Did You Know

• Species of this genus are known for wandering along the jungle floor during the night which is why they are referred to as “wandering spiders”.
• They are alternately called “banana spiders”, a name that they also share with other species because members of this genus have often been found in banana shipments. Research in shipments going to North America showed that 7 of the 135 spiders found in such shipments were of the Phoneutria genus.
• Phoneutria in Greek means murderess, a name perfectly attributed to its aggressive nature.

Other Spiders in this Family

Wandering spiders.

Phoneutria depilata

Phoneutria boliviensis

Phoneutria fera

Phoneutria nigriventer

Southeastern Wandering (Anahita punctulata)

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Brazilian Wandering Spider

Brazilian Wandering Spider , scientifically known as Phoneutria, emerges as a captivating enigma in the realm of arachnids.

Renowned for its formidable reputation as one of the world’s most venomous spiders , Phoneutria embodies a plethora of intriguing traits that have captured the curiosity of enthusiasts and researchers alike.

From its distinctive appearance and neurotoxic venom to its nomadic hunting strategies and unique mating behaviors , this remarkable spider species holds a wealth of fascinating secrets waiting to be unraveled.

Join us as we embark on a journey to explore the captivating world of the Brazilian Wandering Spider, shedding light on its captivating characteristics and dispelling myths that have shrouded its true nature.

1. Taxonomy and Distribution of the Brazilian Wandering Spider

A. scientific classification of phoneutria.

The Brazilian Wandering Spider, scientifically referred to as Phoneutria, occupies a distinct place within the arachnid taxonomy.

Belonging to the family Ctenidae, this spider genus is further categorized into several species, each boasting unique traits and behaviors .

Phoneutria’s taxonomic position not only distinguishes it from its arachnid counterparts but also underscores its intriguing evolutionary journey.

B. Native Habitat in South and Central America

Endemic to the lush landscapes of South and Central America, the Brazilian Wandering Spider finds its natural haven within these diverse regions.

From the rainforests of the Amazon to the tropical stretches of the Caribbean, Phoneutria has adapted to a range of environments over the course of its evolution.

The spider’s ancestral ties to these regions are tightly woven into their behaviors , anatomy, and survival strategies.

C. Preference for Tropical Rainforests and Urban Areas

Within its native territories, the Brazilian Wandering Spider exhibits remarkable versatility in its chosen habitats.

While it thrives amidst the vibrant biodiversity of tropical rainforests, it has also displayed a propensity for urban locales.

Phoneutria’s adaptability has led it to establish a presence in urban areas, where it often finds shelter in crevices, gardens, and even human dwellings.

This adaptability to both wild and urban spaces further showcases the spider’s resilience and capacity to thrive in varying conditions.

2. Physical Characteristics of the Brazilian Wandering Spider

A. size, coloration, and distinctive markings.

The Brazilian Wandering Spider , a creature of remarkable visual intrigue, boasts an array of captivating physical attributes.

Ranging in size from a few centimeters to several inches, Phoneutria showcases a size diversity that reflects the breadth of its genus.

Its coloration varies across species, encompassing shades of brown, black, and gray, often accompanied by intricate patterns and markings that adorn its exoskeleton.

These unique markings serve not only as a visual spectacle but also as essential components of its survival toolkit.

B. Camouflage and Defense Mechanisms

The Brazilian Wandering Spider’s appearance is a masterpiece of evolution, meticulously crafted to ensure both survival and predation .

Its coloration and markings are tailor-made for blending seamlessly into its surroundings, granting it a potent advantage in ambushing prey and evading predators . Moreover, these markings also play a role in its defense mechanisms.

When threatened, Phoneutria adopts a defensive posture, raising its front legs and revealing its striking markings, a visual warning to potential threats. This dual-purpose camouflage and defense strategy exemplify nature’s ingenuity at its finest.

C. Sexual Dimorphism: Unveiling Gender Differences

A fascinating facet of the Brazilian Wandering Spider lies in the realm of sexual dimorphism , where gender-based variations manifest in pronounced ways.

Females tend to be larger and more robust than their male counterparts, showcasing a size disparity that has evolved in tandem with their roles in reproduction and hunting .

Beyond size, other characteristics, such as leg structure and coloration, also exhibit subtle differences between male and female Phoneutria specimens.

This divergence in physical traits adds depth to our understanding of the species’ intricate biology and behavior .

In exploring the physical characteristics of the Brazilian Wandering Spider , we uncover a canvas painted with size diversity, intricate coloration, and unique markings.

These features, finely tuned by evolution, contribute to its prowess in camouflage and defense, while the fascinating interplay of sexual dimorphism further enriches our perception of this captivating arachnid species .

3. Venomous Nature of the Brazilian Wandering Spider

A. potent neurotoxic venom: a silent lethal weapon.

The Brazilian Wandering Spider, known scientifically as Phoneutria, harbors a venomous arsenal that stands as a testament to nature’s intricate design.

This spider’s venom contains a potent concoction of neurotoxic compounds, tailored by evolution to incapacitate its prey swiftly and efficiently.

The neurotoxins interfere with nerve cell communication, leading to paralysis and ensuring that Phoneutria’s quarry is rendered immobile and defenseless, setting the stage for a successful meal.

B. Effects on Prey and Human Hazard

When a victim succumbs to the Brazilian Wandering Spider’s venom , the effects are a symphony of paralysis and predation .

The venom’s impact on the prey’s nervous system results in swift immobilization, offering the spider a decisive advantage in subduing its catch.

While this venomous efficiency is well-adapted for predation, it also underscores the potential danger to humans.

A bite from Phoneutria can lead to a series of neurotoxic reactions, with varying degrees of severity depending on factors such as the individual’s age and overall health.

While human envenomations are relatively rare, they can result in a range of symptoms, from localized pain and swelling to more severe neurological effects.

C. Recorded Cases of Envenomations: Unraveling the Symptoms

Throughout history, documented cases of Phoneutria envenomations have offered insights into the spider’s potential threat to humans .

Symptoms typically include intense pain at the bite site, accompanied by swelling and redness . In some instances, victims have reported systemic reactions, such as muscle cramps, elevated heart rate, and even breathing difficulties.

Swift medical attention and the administration of antivenom have proven effective in mitigating the severity of these symptoms.

These cases serve as a reminder of the delicate balance between the Brazilian Wandering Spider’s potent venom and the potential risks it poses to those who unwittingly encounter it.

4. Hunting and Diet of the Brazilian Wandering Spider

A. hunting techniques and wandering behavior.

The Brazilian Wandering Spider, scientifically known as Phoneutria, unveils a mesmerizing repertoire of hunting techniques that set it apart as a master predator .

Displaying an agile and nomadic behavior , Phoneutria does not confine itself to the confines of a web. Instead, it actively prowls its surroundings, tirelessly searching for potential prey.

This dynamic wandering behavior ensures that its chances of encountering a variety of food sources are maximized, showcasing a strategic approach to sustenance.

B. Active Hunting Triumphs Over Web-Building

Unlike its web-weaving counterparts, the Brazilian Wandering Spider relies on a more hands-on approach to securing its next meal.

While weaving webs might seem an efficient method, Phoneutria’s active hunting strategy offers a distinct advantage in versatility.

By forgoing the constraints of a stationary web, it can tailor its approach to suit different environments and prey types, adapting its tactics on the fly.

This adaptability demonstrates the spider’s remarkable ability to adjust its methods for optimal results.

C. Diverse Prey Spectrum: Insects to Small Vertebrates

Phoneutria’s diet is a testament to its prowess as an opportunistic predator . Its menu spans a diverse range of creatures, from insects like crickets and cockroaches to small vertebrates such as lizards and frogs , and even small rodents.

This wide-ranging palate highlights its ecological significance in controlling various populations within its habitat.

By consuming creatures both large and small, Phoneutria ensures a balanced ecosystem, playing a crucial role in maintaining biodiversity and ecological equilibrium.

5. Mating and Reproduction of the Brazilian Wandering Spider

A. courtship rituals and behaviors: a complex affair.

The Brazilian Wandering Spider, scientifically referred to as Phoneutria, reveals a captivating array of courtship rituals and behaviors that form the cornerstone of its reproductive cycle.

Courtship among these arachnids is a complex affair, involving intricate dances and displays that serve as both communication and assessment.

Male Phoneutria employs a combination of visual cues, vibrations, and tactile interactions to court potential mates.

This elaborate courtship process highlights the significance of precise communication in the delicate dance of reproduction .

B. Cannibalistic Tendencies: A Post-Mating Phenomenon

An aspect that sets Phoneutria’s mating process apart is the notorious cannibalistic tendency exhibited by females after mating.

Following successful mating, females may exhibit an inclination to consume their partners. This seemingly counterintuitive behavior has evolutionary underpinnings.

It is believed that this cannibalistic act not only provides the female with a much-needed nutritional boost but also eliminates potential competitors and safeguards the male’s investment in the next generation.

This intriguing behavior sheds light on the complexities of reproductive strategies within the species.

C. The Unique Mating Plug Phenomenon: A Puzzling Enigma

A distinctive feature in Phoneutria’s reproductive saga is the enigmatic mating plug phenomenon. After mating, male Phoneutria deposit a specialized substance that forms a plug within the female’s reproductive tract.

This plug is believed to serve multiple purposes. It may prevent other males from mating with the female, thus ensuring the successful transmission of the mating male’s genetic material.

Additionally, it might aid in sealing off the female’s reproductive tract, potentially protecting her from external pathogens.

This phenomenon underscores the intricate interplay of biological strategies that contribute to the species’ reproductive success.

6. Human Interaction and Urban Legends of the Brazilian Wandering Spider

A. occasional presence in urban areas: nature in our midst.

The Brazilian Wandering Spider, scientifically known as Phoneutria, has carved a niche for itself not only in the wild but also in the fabric of urban environments.

While its primary habitats are the lush landscapes of South and Central America, Phoneutria occasionally ventures into human -inhabited spaces. Its adaptability allows it to find shelter in gardens, crevices, and even within homes.

This coexistence with humans adds an intriguing dimension to our encounters with this enigmatic arachnid .

B. Debunking Misconceptions: Separating Fact from Fiction

The presence of the Brazilian Wandering Spider has sparked a plethora of misconceptions and exaggerated tales, contributing to the creation of urban legends.

Stories of spiders leaping from banana bunches or hiding under toilet seats have become part of modern folklore, often fueled by sensationalism.

It’s crucial to sift through these tales and recognize that while Phoneutria’s venom is potent, the likelihood of encountering a dangerous encounter is relatively low.

Separating fact from fiction empowers individuals to approach these creatures with accurate knowledge.

C. Importance of Proper Education: Identifying Friend from Foe

Education plays a pivotal role in fostering a harmonious coexistence between humans and the Brazilian Wandering Spider .

Learning to identify and understand the behaviors of Phoneutria species enhances safety for both humans and the spiders themselves.

Instead of succumbing to unwarranted fear, individuals can take steps to reduce the chances of accidental encounters and, if necessary, engage in responsible removal methods.

By arming themselves with knowledge, individuals can navigate encounters with urban-dwelling Phoneutria specimens with confidence and respect.

7. Brazilian Wandering Spider Conservation and Misunderstanding

A. significance of phoneutria in ecosystem dynamics.

The Brazilian Wandering Spider , scientifically termed Phoneutria, assumes a pivotal role within its ecosystem, contributing to a delicate balance of populations and interactions.

As a top-tier predator , it plays a crucial part in controlling insect and small vertebrate populations, preventing unchecked growth that could disrupt the ecosystem’s equilibrium.

By maintaining these population dynamics, Phoneutria ensures the health and stability of its habitat, highlighting its significance beyond its ominous reputation.

B. Impact of Fear and Misunderstanding: Hindrances to Conservation

Despite its ecological contributions, the Brazilian Wandering Spider often falls victim to fear-driven misconceptions that negatively impact conservation efforts.

Misunderstandings surrounding its behavior and potential danger can lead to unwarranted extermination campaigns and habitat destruction.

Fear-driven reactions not only disrupt the natural balance but also hinder opportunities to study and appreciate the species for its ecological significance.

Addressing these misconceptions is crucial to ensuring the spider’s survival and maintaining the health of its ecosystems.

C. Efforts to Dispel Myths and Promote Coexistence

Efforts to conserve the Brazilian Wandering Spider are interwoven with endeavors to educate and dispel myths.

By providing accurate information and dispelling exaggerated tales, conservationists aim to reshape public perception.

Collaborative initiatives emphasize coexistence, highlighting the importance of responsible behavior when encountering Phoneutria.

Educating communities about the spider’s role, behavior, and conservation status fosters an environment where fear gives way to appreciation, and where balanced cohabitation becomes a reality.

8. Research and Medical Significance of the Brazilian Wandering Spider

A. ongoing scientific research on phoneutria venom.

The Brazilian Wandering Spider , Phoneutria, has garnered significant attention from the scientific community due to the unique properties of its venom.

Ongoing research delves into the intricate composition of the venom, aiming to unlock its mysteries and potential applications in various fields.

The diverse array of compounds within the venom, particularly its neurotoxic components, has attracted interest for their potential medical and therapeutic implications.

B. Antivenom Development and Therapeutic Prospects

One of the most promising areas of research surrounding Phoneutria lies in the development of antivenoms and therapeutic agents.

The venom’s potent neurotoxic effects on the nervous system have spurred efforts to create targeted treatments for conditions such as chronic pain and neurological disorders .

Additionally, the potential for antivenoms holds promise in mitigating the effects of envenomations, offering a lifeline for individuals who encounter these spiders .

This focus on harnessing the venom’s properties for positive medical outcomes highlights the transformative potential within this enigmatic arachnid .

C. Balanced Perspectives: Navigating Ethical and Scientific Endeavors

While research on the Brazilian Wandering Spider’s venom offers tremendous potential, it necessitates a balanced perspective.

As researchers probe the venom’s properties, ethical considerations arise, including the well-being of the spiders and their ecosystems.

A holistic approach acknowledges the value of understanding Phoneutria’s natural behaviors and conserving its habitats.

This balanced perspective extends to utilizing the venom’s potential responsibly, ensuring that breakthroughs are achieved while respecting the complex interplay of science and nature.

9. Frequently Asked Questions about the Brazilian Wandering Spider

What is the brazilian wandering spider.

The Brazilian Wandering Spider , scientifically known as Phoneutria, is a venomous arachnid found in South and Central America. It’s notorious for its potent venom and is considered one of the most venomous spiders in the world.

Is the Brazilian Wandering Spider dangerous to humans?

Yes, the Brazilian Wandering Spider’s venom contains potent neurotoxins that can cause a range of symptoms in humans , from localized pain and swelling to more severe reactions. While bites are relatively rare, it’s advisable to exercise caution when encountering these spiders.

What is the spider’s habitat?

The Brazilian Wandering Spider is native to tropical rainforests of South and Central America. However, it’s adaptable and can also be found in urban areas, such as gardens and houses.

How does the Brazilian Wandering Spider hunt?

Unlike many spiders that build webs, Phoneutria is an active hunter. It roams its environment in search of prey, relying on its keen senses to detect vibrations and movements.

Are Brazilian Wandering Spiders aggressive toward humans?

Brazilian Wandering Spiders are not naturally aggressive towards humans and will typically only bite in self-defense. However, caution is advised, especially in areas where these spiders are known to inhabit.

Can the Brazilian Wandering Spider’s venom be used for medical purposes?

Yes, research is ongoing into the potential medical applications of Phoneutria’s venom. Its neurotoxic properties have sparked interest in pain management and neurological treatments.

Is the spider’s reputation for crawling into banana shipments true?

While there have been stories of Brazilian Wandering Spiders being found in shipments of bananas, these occurrences are extremely rare. Spiders are unlikely to survive the conditions of shipping and storage.

How can I stay safe around Brazilian Wandering Spiders?

To stay safe, it’s important to be cautious when encountering spiders in their natural habitat. Avoid provoking or handling them, especially if you’re unsure of their identity. If you suspect you’ve been bitten, seek medical attention promptly.

Are there any efforts to conserve the Brazilian Wandering Spider?

Conservation efforts for the Brazilian Wandering Spider are intertwined with public education and dispelling myths. Recognizing its role in ecosystems and promoting coexistence are essential steps in preserving this unique species.

What can I do if I find a Brazilian Wandering Spider in my home?

If you encounter a Brazilian Wandering Spider in your home, it’s advisable to contact local pest control professionals who can safely remove the spider without causing harm.

In the intricate tapestry of nature, the Brazilian Wandering Spider , Phoneutria, emerges as a creature of both fascination and caution.

Its venomous nature and captivating behaviors have earned it a place among the most enigmatic arachnids .

As we continue to explore its world, debunk myths, and understand its vital role in ecosystems, we find a delicate balance between awe and respect.

Armed with knowledge, we navigate the realm of Phoneutria, appreciating its complexity while fostering coexistence, a testament to the intricate dance between humans and the natural world.

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The Brazilian Wandering Spider

The Brazilian Wandering Spider, also known as the armed spider or banana spider, is a venomous arachnid found in Central and South America. It is considered one of the most dangerous spiders in the world. The spider is medium to large in size, with a leg span of up to 6 inches. It has a hairy body, long and slender legs, and displays a variety of colors and patterns, including a distinctive red or orange mark on its abdomen. Unlike most spiders, it does not build a web; instead, it wanders the forest floor or hides in crevices during the day, making it particularly dangerous to humans.

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Brazilian wandering spider : diet, predators, aggression, and defensive behaviors, what do brazilian wandering spiders eat.

Brazilian Wandering Spiders are carnivorous predators, feeding primarily on insects like crickets, cockroaches, and beetles. They are also known to hunt small vertebrates such as lizards, frogs, and mice. These spiders may also catch other spiders or even small snakes as prey. Their venom helps to immobilize and digest their food.

Do Brazilian Wandering Spiders have any predators?

While Brazilian Wandering Spiders are apex predators in their ecosystems, they do have some predators. Birds like owls and hawks have been observed preying on these spiders. Additionally, snakes and certain types of wasps are known to feed on these spiders. However, due to their venomous bite and agile movements, Brazilian Wandering Spiders are not an easy meal for most predators.

Are Brazilian Wandering Spiders aggressive?

Brazilian Wandering Spiders are known to be highly aggressive when threatened or provoked. They will not hesitate to bite if they feel cornered or in danger. However, they will typically give warning signs such as rearing up on their hind legs and exposing their fangs before attacking. It is important to exercise caution and avoid provoking these spiders in their natural habitat.

Do Brazilian Wandering Spiders fight with other species?

Brazilian Wandering Spiders are solitary creatures and will generally avoid confrontation with other spiders or animals, unless it is for hunting or self-defense. They are more likely to engage in combat with prey or potential threats than with members of their own species. However, if two male Brazilian Wandering Spiders encounter each other during mating season, they may engage in a territorial dispute.

How do Brazilian Wandering Spiders defend themselves?

When faced with a threat, Brazilian Wandering Spiders have several defense mechanisms at their disposal. They may exhibit aggressive behavior, raising their front legs and exposing their fangs as a warning. If this does not deter the threat, they are capable of delivering a venomous bite that can cause severe pain and potentially be fatal to humans. Additionally, these spiders are agile and quick, enabling them to evade predators or escape dangerous situations.

What is the biggest weakness of Brazilian Wandering Spiders in a fight?

Despite their potent venom and aggressive nature, Brazilian Wandering Spiders have a vulnerability in their soft exoskeleton. Their bodies are not as robust as some other arachnid species, making them more susceptible to physical damage in a fight. Predators that can overpower them with sheer strength, like large birds or snakes, may pose a serious threat to these spiders. Additionally, injuries sustained in combat can hinder their ability to hunt and survive in their environment.

Fun Fact : This spider has been listed in the Guinness World Records as the world's most venomous spider, as its venom can cause severe pain, swelling, and even paralysis or death in humans if untreated.

Fun Fact : Male Brazilian Wandering Spiders often exhibit a unique and fascinating courtship ritual, which involves drumming or tapping their legs on the leaves to attract females, showcasing their agility and fitness in the process.

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Brazilian wandering spider phoneutria spp.  is actually a genus with five known similar species whose members are highly venomous. they include some of the relatively few species of spiders that present a threat to human beings. the brazilian wandering spider (phoneutria fera) can grow to have a leg span of up to 4-5 inches..

These spiders are notorious both due to their toxic venom, and because they are not reluctant to attack people who appear threatening.

Of the five species known, P. nigriventer and P. fera most frequently receive mention in mass-media publications. P.nigriventer species are responsible for most cases of venom intoxication in Brazil because this species is commonly found in highly populated areas of Brazil, namely the South-eastern states: São Paulo, Minas Gerais, Rio de Janeiro and Espírito Santo.

The P. fera is native to the northern portion of South America, especially the Brazilian Amazônia, Venezuela and French Guiana.

Photo right: P. nigriventer female (Sao Paolo, Brazil morph). 

Recent studies suggest that these spiders only inject venom in approximately one-third of their bites and may only inject a small amount in another third. However, research in this area is hindered by the difficulty of identifying particular subspecies. Thus the effects of the bites from these spiders are hard to predict when based on sketchy information or if the spider has not been identified definitively.  

Bites from these spiders may result in only a couple of painful pinpricks to full-blown envenomation. In either case, people bitten by a Phoneutria or any Ctenid should seek immediate emergency treatment as the venom is possibly life threatening.

Photo left: Dead P. reidyi

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The Phoneutria fera and nigriventer  are the two most commonly implicated as the most virulent of the Phoneutria spiders. The Phoneutria not only has a potent neurotoxin, but is reported to have one of the most excruciatingly painful envenomations of all spiders due to its high concentration of serotonin.  

Brazilian Wandering Spiders are extremely fast, extremely venomous, and extremely aggressive and are ranked among the most venomous spiders known to man. In fact, the Brazilian Wandering Spider is the most venomous spider in the New World! In South America, these true spiders are commonly encountered in peoples' homes, supposedly hiding in peoples' shoes, hats, and other clothes. It does not remain on a web, rather, it wanders the forest floor, which is how it got its name.

The Brazilian Wandering Spider has another name - the Banana Spider and it was given this name  because there have been cases where these spiders unintentionally appeared on banana boats heading for the United States.

Click here for more photos of Wandering Spiders.

Information and pictures were taken from children's projects and where credited to that child does not claim to be original information. Where possible, permission to reproduce has been sought. Any infringement of copyright is purely unintentional.

Brazilian Wandering Spider Facts: What Happens If It Bites You?

Brazilian wandering spiders belong to the genus Phoneutria  and are represented by eight spider species that are native to Central America and South America. This spider group is also collectively known as armed spiders and banana spiders. In Brazil, they are locally known as "aranha armadeira" which means armed spider. With these, some people often wonder if a person can survive after being by a member or species of this group.

What is a Brazilian Wandering Spider?

The genus Phoneutria , which the Brazilian wandering spider  and related spider species belong to, was first described in 1833 when two species was included on it. The following century saw various scientists to move the Phoneutria species between genera Phoneutria  and Ctenus . In 1936, Mello-Leitao restored Phoneutria  and currently contains eight species, as reported by the University of Florida.

Banana spiders, a name given to the arachnid group due to their frequent presence on banana leaves, are large and robust arachnids in the family Ctenidae .   They resemble the morphological appearance of wolf spiders. In addition, their body length can grow ranging from 17 and 48 millimeters and their leg span can reach 180 millimeters. Their distinct color ranges from light brown, brown, or grey. Furthermore, the natural habitats of armed spiders are forests.

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What Happens If It Bites You?

The natural prey of Brazilian wandering spiders includes small animals like crickets, mantids, and katydids, and larger ones like bats, frogs, and lizards. However, they can still bite humans and other animals not native in their habitats. In the past, scientists have identified that the bite of banana spiders living in Central and South American rain forests can lead to shortness of breath and excessive salivation.

According to wildlife experts, a Brazilian wandering spider bite can also lead to other serious symptoms, including increased blood pressure, above-normal pulse, and unusual respiratory rate, as well as extreme pain, hours-long penile erection, and death, in some cases. These spiders inject neurotoxin venom to its bitten victim and can be deadly to humans, particularly for children. However, it is not the world's deadliest spider.

Venomous Spider

In a study published in the journal Frontiers  in February 2023, researchers stated that the Brazilian wandering spider is amongst the world's most dangerous venomous spiders in the world. In Brazil, there have been an estimated 4,000 envenomation accidents of Phoneutria nigriventer  spider species each year in Brazil. Additional symptoms were also observed, including blurred vision, priapism, and vomiting.

The armed spider only follows the world's most venomous spider, which according to the Guinness World Records , is the Sydney funnel-web spider ( Atrax robustus ).

Like the Brazilian wandering spider, the venom of A. robustus  can be neutralized by anti-venoms but some cases still lead to deaths when these arachnids bite a human, who did not receive any medical attention. Experts also weigh that the mortality of venom depends on the amount that enters a human body.

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The brazilian wandering spider: threats and treatments.

Imagine being bitten by a spider that not only causes excruciating pain, but also induces a painful and prolonged erection. This peculiar arachnid is no other than the Brazilian Wandering Spider, a creature that strikes fear into the hearts of many. This article explores the threats posed by this venomous spider and examines the treatments available for its bite. Prepare to discover the terrifying world of the Brazilian Wandering Spider and the measures taken to combat its deadly effects.

Table of Contents

Overview of the Brazilian Wandering Spider

Introduction to the Brazilian Wandering Spider

The Brazilian Wandering Spider, scientifically known as Phoneutria, is a species of venomous spider found primarily in South and Central America, with Brazil being its native habitat. These spiders are known for their distinct hunting techniques, potent venom, and the ability to wander, hence their name. With its aggressive nature and potentially lethal bite, the Brazilian Wandering Spider poses a significant threat to humans and animals alike.

Preferred Habitat and Distribution

Brazilian Wandering Spiders are adaptable creatures that can thrive in various habitats, ranging from tropical rainforests to urban areas. They prefer dark and secluded areas like tree stumps, piles of leaves, and crevices, typically found in the wilderness. However, due to deforestation and human encroachment, these spiders have also adapted to urban environments, often found hiding in woodpiles, sheds, and even inside homes.

Physical Characteristics

The Brazilian Wandering Spider is a large arachnid, with a leg span that can reach up to 6 inches. They have a brownish appearance with darker markings, aiding in their camouflage amidst bark and leaves. These spiders possess strong legs, enabling them to move quickly and gracefully. The most distinguishing feature of the Brazilian Wandering Spider is their characteristic defensive posture, where they raise their front legs to display their fangs.

Behavior and Hunting Techniques

Unlike most spiders that build webs for hunting, Brazilian Wandering Spiders are active hunters. They spend their nights on the move, searching for prey and avoiding potential predators. These spiders have excellent eyesight and rely on their acute senses to detect movements and vibrations. When hunting, they employ a unique technique known as “lurking,” where they stay hidden, waiting for their prey to approach before quickly pouncing on it.

Diet of Brazilian Wandering Spiders

Brazilian Wandering Spiders have a varied diet, which includes insects, small rodents, and even lizards. Their venomous bite immobilizes their prey, making it easier for the spider to handle and consume. While they primarily feed on live prey, these versatile spiders can also scavenge for food when necessary, increasing their chances of survival in harsh environments.

Venomous Threats Posed by Brazilian Wandering Spiders

Potency of brazilian wandering spider venom.

The venom of the Brazilian Wandering Spider is considered one of the most potent among spider species. It contains a neurotoxin called PhTx3, which affects the nervous system, causing severe pain, muscle spasms, and potentially life-threatening reactions. Due to its toxicity, the venom of this spider is not only harmful to humans but can also be lethal to animals, including pets.

Signs and Symptoms of Spider Bites

When bitten by a Brazilian Wandering Spider, the symptoms can vary depending on the individual’s sensitivity and the amount of venom injected. Common signs of spider bites include intense pain, redness, swelling, and local tissue damage. In severe cases, individuals may experience systemic effects like muscle cramps, increased heart rate, sweating, and even difficulty breathing. It is crucial to seek medical attention immediately if bitten by this spider.

Health Risks and Potential Complications

Being bitten by a Brazilian Wandering Spider can lead to various health risks and potential complications. The neurotoxic effects of the venom can cause paralysis, respiratory failure, and in extreme cases, death. Additionally, some individuals may develop allergic reactions to the venom, further exacerbating the severity of the bite. Prompt medical treatment is essential to minimize the risks and complications associated with these spider bites.

Comparison to other Venomous Spiders

Compared to other venomous spiders, such as the Black Widow or Brown Recluse, the Brazilian Wandering Spider’s bite is known to be more lethal due to its potent venom. While the Black Widow and Brown Recluse spiders are found in different regions, their venom can cause severe local tissue damage and systemic symptoms as well. Each spider species presents unique risks, and understanding their differences is crucial in providing appropriate medical treatment.

Fatalities and Incidents Reported

Fatalities related to Brazilian Wandering Spider bites are rare, thanks to the availability of antivenom and timely medical interventions. However, incidents of spider bites resulting in immediate hospitalization and severe complications have been documented. Particularly vulnerable to these bites are children, the elderly, and those with underlying health conditions. Prompt reporting and proper management of spider bites are crucial to prevent tragic outcomes.

Medical Treatments for Brazilian Wandering Spider Bites

Emergency response and first aid measures.

In the event of a Brazilian Wandering Spider bite, immediate action is necessary. First and foremost, it is essential to stay calm and seek medical help without delay. While waiting for medical professionals to arrive, follow basic first aid measures, including cleaning the wound with mild soap and water, applying a cold compress to reduce swelling, and keeping the affected limb immobilized to minimize venom spread.

Antivenom Administration for Spider Bites

Antivenom is the primary treatment for Brazilian Wandering Spider bites. It contains antibodies that neutralize the venom’s effects, reducing pain and preventing further complications. Medical professionals will carefully administer the antivenom, closely monitoring the patient’s vital signs and ensuring appropriate dosage. Antivenom therapy is vital in counteracting the potent neurotoxin and providing the best chance for a successful recovery.

Management of Pain and Swelling

To alleviate pain and reduce swelling associated with spider bites, various medications can be prescribed. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to decrease inflammation and relieve discomfort. In some cases, opioids may be necessary to manage severe pain. Applying ice packs to the bite site and elevating the affected limb can also help reduce swelling.

Treatment Approaches for Systemic Effects

When systemic effects occur due to a Brazilian Wandering Spider bite, additional treatment approaches are required. Muscle relaxants and anticonvulsant medications may be administered to control muscle spasms and reduce the risk of convulsions. Supportive care, such as intravenous fluids and oxygen therapy, may also be provided to maintain hydration and ensure respiratory stability.

Long-Term Effects and Follow-Up Care

Even after the initial treatment of a Brazilian Wandering Spider bite, long-term effects may persist. Some individuals may experience residual pain, muscle weakness, or psychological trauma. Follow-up care is vital to monitor and manage any lingering symptoms. Physical therapy and counseling may be recommended to aid in rehabilitation and promote psychological well-being.

Prevention and Control Measures

Understanding spider behavior and habitats.

Understanding the behavior and habitats of Brazilian Wandering Spiders is crucial for effective prevention and control. Being aware of their preference for dark, secluded areas allows individuals to take proactive measures to minimize encounters. Regularly inspecting and cleaning potential hiding spots and sealing any gaps or cracks in homes and buildings can significantly reduce the chances of a spider infestation.

Spider Bite Prevention Tips

To prevent spider bites, adopting certain preventive measures is advisable. Avoid reaching into dark spaces without proper visibility, especially when gardening or working with woodpiles. Shake out clothing and shoes before wearing them, as spiders may seek refuge in these items. Using gloves when handling items in potential spider habitats can also provide a line of defense against accidental bites.

Safety Measures for Homes and Buildings

Creating a spider-free environment within homes and buildings can be achieved through implementing safety measures. Regularly clean and declutter living spaces, as spiders are attracted to dark and undisturbed areas. Installing screens on windows and doorways can prevent spiders from entering, and using weatherstripping to seal gaps will minimize entry points. Additionally, keeping outdoor lights off or changing the color to be less attractive to insects can also deter spiders.

Protective Clothing and Gear

When venturing into areas known for spider activity, wearing protective clothing and gear is essential to minimize the risk of bites. Long-sleeved shirts, long pants, and closed-toe shoes can provide a physical barrier between the spider and the skin. Additionally, using gloves, hats, and face shields can further protect vulnerable areas, reducing the chances of accidental bites.

Insecticides and Pest Control Methods

In cases where spider infestations become significant and pose a threat, the use of insecticides and professional pest control methods may be necessary. It is important to follow local regulations and recommendations when applying insecticides, as some may be harmful to humans and pets. Seeking the assistance of licensed pest control experts ensures effective treatment while prioritizing safety.

Research and Studies on Brazilian Wandering Spiders

Scientific studies and species classification.

Scientific studies play a crucial role in expanding our knowledge of Brazilian Wandering Spiders. Researchers conduct studies to better understand their taxonomy, behavior, and venom composition. Species classification helps identify specific variations within the Phoneutria genus, allowing for more targeted research and providing a foundation for conservation efforts.

Venom Extraction and Composition

Extracting and analyzing the venom of Brazilian Wandering Spiders is essential for developing effective antivenom and understanding the biochemical properties of the venom. Researchers aim to identify the specific toxins present, their mechanisms of action, and potential therapeutic applications. Studying venom composition can uncover valuable insights into the spider’s hunting strategies and aid in the development of novel pharmaceuticals.

Antivenom Development and Efficacy

Research on antivenom development focuses on improving the efficacy and safety of existing treatments. Scientists work to refine antivenom formulations, ensuring they neutralize the spider’s venom effectively. Testing the antivenom’s efficacy against various species of Brazilian Wandering Spiders is crucial to provide broad coverage and maximize the chances of successful treatment.

Environmental Impact and Conservation

Understanding the environmental impact of Brazilian Wandering Spiders is essential for effective conservation strategies. Research delves into the spider’s role in the ecosystem, its interactions with other species, and the potential consequences of population decline. By assessing their conservation status and identifying threats, scientists and policymakers can develop measures to protect this species and preserve its natural habitats.

Future Research Directions

As scientific advancements continue, future research on Brazilian Wandering Spiders will focus on areas such as genetic studies, venom evolution, and behavior analysis. Deepening our understanding of their genetics can provide insights into their adaptability and evolutionary history, aiding in conservation efforts. Additionally, studying behavioral patterns can enhance our ability to predict their movements and prevent human encounters.

Emerging Concerns and Cases of Brazilian Wandering Spider

Global spread and entry into new regions.

The global spread of the Brazilian Wandering Spider is a growing concern. Due to international trade and transportation, these spiders have been inadvertently introduced to regions outside their native habitat. Their ability to adapt to new environments increases the risk of establishing invasive populations, impacting local ecosystems and potentially posing a threat to human health.

Importance of Surveillance and Reporting

Surveillance and reporting systems are vital in monitoring and preventing the spread of Brazilian Wandering Spiders. Prompt and accurate reporting of potential sightings ensures swift action can be taken to mitigate the risks associated with these spiders. Encouraging public involvement and providing education on spider identification can help improve surveillance efforts and enable effective measures to be implemented.

Documented Cases Outside Brazil

While the Brazilian Wandering Spider is primarily found in Brazil, documented cases of encounters and bites have been reported in other countries. This highlights the potential for these spiders to establish populations beyond their native range and emphasizes the need for international cooperation in addressing this emerging concern. Sharing knowledge and experiences across borders is crucial in managing and preventing spider-related incidents.

Impact on Tourism and International Trade

The presence of Brazilian Wandering Spiders in areas heavily reliant on tourism and international trade can have significant economic implications. Fear of spider encounters and bites may deter tourists and affect the tourism industry. Moreover, the risk of transporting spiders through international trade, particularly in goods such as fruits or plants, poses a biosecurity concern that requires strict monitoring and prevention measures.

Legal and Regulatory Measures

To address the emerging concerns associated with the Brazilian Wandering Spider, legal and regulatory measures are necessary. Countries need to establish and enforce regulations on the import and export of potentially infested goods, ensuring adequate inspection protocols are in place. Collaboration between governments, organizations, and industries is crucial in establishing effective policies to minimize the risks posed by these spiders.

Interactions and Reactions from Local Communities

Fear and anxiety-related reactions.

The presence of Brazilian Wandering Spiders often elicits fear and anxiety among local communities. The aggressive behavior and potential dangers associated with these spiders contribute to a negative perception. Understanding the psychological impact of these fears is essential to develop educational programs and support services that address community concerns and promote emotional well-being.

Education and Awareness Programs

Educational initiatives and awareness programs play a vital role in mitigating the fears surrounding Brazilian Wandering Spiders. Providing accurate information about the spiders, their behavior, and the appropriate actions to take in case of encounters or bites can help alleviate anxiety and empower individuals to respond effectively. School programs, community workshops, and online resources are valuable tools to disseminate information and promote awareness.

Myths, Folklore, and Cultural Beliefs

Brazilian Wandering Spiders often find themselves entwined in myths, folklore, and cultural beliefs. Some local communities associate these spiders with superstitions and consider them to be omens or symbols of danger. Understanding these cultural beliefs and engaging in respectful dialogue is crucial to dispel myths, foster a better understanding of the spiders, and promote a harmonious coexistence.

Spider as a Symbol in Art and Media

The intriguing nature of the Brazilian Wandering Spider makes it a subject of fascination in art, literature, and media. Artists incorporate the spider’s image into various forms of expression, creating artwork that captures its mystique and intricate details. It serves as a reminder of the spider’s significance in both natural and cultural contexts, sparking conversations and encouraging further exploration.

Local Efforts for Spider Conservation

Communities residing in areas populated by Brazilian Wandering Spiders often play a crucial role in their conservation. Local conservation efforts may involve initiatives such as promoting sustainable land use, raising awareness about the importance of biodiversity, and establishing protected areas or nature reserves. Engaging local communities in spider conservation fosters a sense of ownership and shared responsibility for safeguarding these fascinating creatures.

Comparison with Other Dangerous Spider Species

Brown Recluse Spider

The Brazilian Wandering Spider and the Brown Recluse Spider both pose threats to humans, but they have distinct characteristics. While the Brazilian Wandering Spider is known for its wandering nature and highly potent neurotoxic venom, the Brown Recluse Spider is recognized for its reclusive behavior and venom that can cause necrotic skin lesions. Understanding the differences between these species is crucial in providing appropriate medical treatment for bites.

Black Widow Spider

Both the Brazilian Wandering Spider and the Black Widow Spider are venomous, but their venom composition and effects differ. While the Brazilian Wandering Spider’s venom primarily affects the nervous system, the Black Widow Spider’s venom contains neurotoxins that target the neuromuscular junctions. Recognizing the symptoms and seeking appropriate medical treatment are essential in managing bites from these spiders.

Sydney Funnel-Web Spider

The Brazilian Wandering Spider and the Sydney Funnel-Web Spider are both known for their potent venom and aggressive behavior. However, the Sydney Funnel-Web Spider is native to Australia, while the Brazilian Wandering Spider is found in South and Central America. Despite their geographical differences, both spiders require urgent medical attention in the case of bites due to the potential severity of their venom.

Redback Spider

The Redback Spider, native to Australia, is similar to the Brazilian Wandering Spider in terms of venom potency and potentially lethal bites. They both belong to the family of spiders known for their neurotoxic venom. While the Brazilian Wandering Spider is more active and known for its wandering behavior, the Redback Spider tends to build webs and wait for their prey. Understanding their distinct characteristics is essential in providing targeted medical treatment.

Taipan Spider

The Taipan Spider, also known as the Coastal Taipan or Australian Tarantula, is another venomous spider species found in Australia. Its unique venom composition makes it distinct from the Brazilian Wandering Spider. The Taipan Spider is known for its highly potent neurotoxic venom, but its behavior and physical characteristics differ significantly from those of the Brazilian Wandering Spider. Recognizing the differences helps in accurately identifying and managing spider encounters.

Misidentification and Popular Misconceptions

Confusion with harmless spider species.

Spider misidentification is a common occurrence, leading to unnecessary panic and fear. The Brazilian Wandering Spider may be mistaken for non-venomous species, such as harmless Huntsman or Wolf spiders, due to a superficial resemblance. Educating the public about distinguishing features and encouraging accurate identification can prevent unnecessary concern and promote a better understanding of these spiders.

Spider Hoax and Urban Legends

Urban legends and hoaxes involving spiders, including the Brazilian Wandering Spider, have contributed to public misconceptions. Sensationalized stories on social media or unreliable sources often exaggerate the dangers associated with these spiders, perpetuating unnecessary fears. Encouraging critical thinking and relying on reputable sources for information can help dispel myths and prevent the spread of false information.

Exaggerated Claims and Sensationalism

Exaggerated claims and sensationalism in media portrayals of the Brazilian Wandering Spider can contribute to public hysteria. Highlighting the spiders’ aggressive behavior and potential lethality without providing accurate context can create unnecessary panic. Promoting responsible journalism that presents factual information and provides balanced perspectives is essential to ensure accurate public understanding of these spiders.

Social Media Impact on Public Perception

Social media platforms have a significant influence on public perception and understanding of the Brazilian Wandering Spider. Misinformation can spread rapidly, contributing to fear and misunderstanding. It is crucial to encourage responsible sharing of information, verify facts before sharing, and promote scientific literacy to combat the spread of inaccuracies and ensure accurate portrayals of these spiders.

Expert Clarifications and Reliable Sources

Experts and reliable sources play a vital role in clarifying misconceptions surrounding the Brazilian Wandering Spider. Educating the public about the spiders’ behavior, venom potency, and risks through reputable sources is crucial. Scientists, researchers, and medical professionals can provide accurate and evidence-based information, addressing concerns and dispelling myths surrounding these spiders.

Conservation Efforts and Habitat Protection

Need for conservation initiatives.

Conservation initiatives are crucial to protect the Brazilian Wandering Spider and its natural habitats. The preservation of biodiversity, including these unique arachnids, is essential for maintaining healthy ecosystems. By recognizing the ecological importance of spiders and their role in pest control, conservation efforts can be integrated into broader strategies aimed at preserving the planet’s biodiversity.

Preserving Natural Habitats

Preserving the natural habitats of Brazilian Wandering Spiders is paramount to their long-term survival. Protecting forests, wetlands, and other ecosystems ensures the spiders have suitable areas to thrive. Implementing sustainable land use practices and conservation policies that consider the needs of these spiders and their habitats can help safeguard their populations for future generations.

Captivity Breeding Programs

In certain cases, captivity breeding programs may be established to support the conservation of Brazilian Wandering Spiders. These programs provide controlled environments for breeding and rearing these spiders, ensuring genetic diversity and maintaining healthy populations. Collaboration between reputable institutions and regulatory bodies is crucial in developing and implementing successful breeding programs.

Community Involvement in Spider Protection

Engaging local communities in spider protection efforts fosters a sense of responsibility and promotes the overarching goal of conservation. Encouraging the participation of local residents in monitoring spider populations, reporting sightings, and supporting sustainable land use practices can enhance the effectiveness of conservation initiatives. Community involvement ensures that the conservation efforts reflect the needs and values of the people living in close proximity to these spiders.

Role of Zoos, Sanctuaries, and Research Institutions

Zoos, sanctuaries, and research institutions play a vital role in the conservation of Brazilian Wandering Spiders. These establishments provide controlled environments for the spiders, conduct research, and educate the public. By supporting scientific studies, raising awareness, and participating in breeding programs, these institutions contribute to the long-term conservation of these fascinating arachnids.

In conclusion, the Brazilian Wandering Spider, with its potent venom and unique hunting techniques, poses both a venomous threat and an ecological fascination. Understanding its behavior, venom, and appropriate medical treatments is crucial in mitigating risks associated with potential encounters. Conservation efforts, public education, and responsible reporting play essential roles in preserving the natural habitats of these spiders and dispelling myths surrounding them. By promoting a better understanding of the Brazilian Wandering Spider, we can foster a sense of coexistence and ensure the well-being of both humans and these remarkable arachnids.

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Mike Benkert

I'm a bug enthusiast and creator of BugsWorldWide, a blog sharing his 15 years of my experience caring for bugs. I've traveled the world bird watching and I'm committed to helping others with bug care. Contact me at [email protected] for assistance.

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Brazilian Wandering Spider

• Development & Reproduction
• Classification/Phylogeny

Phoneutria fera

This website is home to the deadliest spider known to man: the Brazilian Wandering Spider. I hope you learn a lot about this intriguing, beautiful, yet dangerous creature and come back soon!!

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FACTS ABOUT Wandering spider

Brazilian wandering spider

Phoneutria genus.

BACK TO ALL WILDLIFE

Did you know? Our Rainforest Expeditions guests find the relatives of these shy, eight-legged creatures on night hikes!

Brazilian wandering spider fun facts.

• Most toxic spider venom is known : The venom of at least one species of Phoneutria is much more toxic than the Black Widow Spider and can easily kill mice with one bite. Human fatalities in Brazil are an extremely rare occurrence.
• No web : Unlike many other spiders, the wandering spiders don’t build webs but actively search for their prey.
• The banana spider : Wandering spiders occasionally turn up in shipments of bananas! One such stowaway actually bit a man in England in 2005. He survived but spent a week in the hospital!
• Understory predator : These spiders are active, aggressive predators that feed on large insects, small lizards, mice, and frogs.

How to plan your Amazon jungle travel to see Brazilian Wandering Spiders and other jungle wildlife

• Go on a night hike: These large spiders are most active at night. We have nightly hikes in the rainforest with trained guides so you can see wandering spiders and other nocturnal jungle animals.
• Make science happen with AmazonCam: even if Amazon Travel is not in your short-term plans, you can connect with Amazon wildlife!
• And of course, if you´re thinking (or even dreaming) of Amazon jungle Travel, drop by to chat with the Amazon Travel experts . We will help you get there.

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• ANHINGA (Anhinga anhinga) ANHINGA (Anhinga anhinga) Height 81 - 91 cm Weight 1.350 Kg Lodge Posada Amazonas

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What our guest say

• Valuation Excellent

Mo Bashagha Feb 2024

Nelehkoh9 feb 2024, jen101382 feb 2024, vigs feb 2024, shovan bhattacharrya feb 2024, shovan b feb 2024, michele feb 2024, rahul s jan 2024, amina aziz jan 2024, voyage51682856837 jan 2024, sundar v jan 2024, tina a jan 2024.

A truly magical experience. It’s set in a completely unique location in the middle of the jungle with no other lodges around. The guide we had (Jarinson) was the best, so so knowledgeable, experienced and lovely to spend the time with. The lodge itself is beautiful and food was great too. Would highly recommend. Read all

Interesting bus and river boat rides bring you to Posada Amazonas on the Tambopata River. It’s managed by the Ese Eja indigenous community. Luis M., our guide, helped us observe birds and learn about plants and other animals. A canopy tower, clay lick and oxbow lake are highlights. All personnel are extremely kind and researchers give short lectures in the evening. The food is delicious! Excellent mosquito netting in rooms! Read all

Wow where do I even begin. This was one of the most unique and special experiences we've ever had. You are smack dab in the middle of nowhere, deep in the Amazon jungle. Surrounded by plants and animals of all kinds and some of the most breathtaking scenery you can imagine. And in the company of scientists doing conservation work all around you. The facility is gorgeous beyond belief. Everything is so thoughtfully prepared, from water servers everywhere to comfy couches to hammocks to raised walkways so you can pad around barefoot without feeling like you're going to step on a scorpion. The meals are positively gourmet. They have delicious fresh juice out for you when you come back from your hikes. We spend 2 days there and I genuinely feel like I saw the jungle. 2-3 excursions a day with a private guide to show you everything from plants to birds to animals to a very tall tower where you can watch the sunset over the canopy. We only had 3 people in our group but I believe there can be up to 7. You have the same guide your whole trip so you really get to know them. Johan was our guide and he was wonderful. And I do believe the number of excursions/type/length can be adjusted based on your groups physical ability. The rooms are beautiful and comfy and they help you prepare mosquito netting at night so you can be comfortable. There's a full bar, in the middle of the rainforest. At night there are short (30 min) lectures you can go to if you want where the scientists talk about their work. Fascinating. We loved that the center was very eco conscious and put a lot of effort into being low impact while also offering a truly luxurious experience. That being said. Do yourself a favor and read the web site. This experience will not be for everyone. Ppl posting negative comments here about the heat, bugs, open rooms, etc did not do their homework. You are far, far inside pristine Amazon jungle. It is hot, humid, rainy, and there are bugs. You can expect to use your lovely shower a few times a day to cool off. Fortunately you have lots of down time during the heat of the day to rest under the ceiling fan in your room. There were lots of grasshoppers, moths etc around our room but honestly we didn't have many issues with biting insects or mosquitos despite visiting during the rainy season (we did use bug spray). Your room has one open wall that faces nature. Yes, technically than means someone could see you walking around naked in your room, but you are 15 feet up in the air and facing directly into thick jungle, there is no one out there besides birds and monkeys to see you. They do cut the brush back so nothing except maybe some birds could get into your room. The sounds are magical at night and during the day. It's hot especially if you go during the rainy season as we did. If you hate bugs or can't handle life without air conditioning, this is not for you. Truthfully we had no issues sleeping. Ventilation is another big benefit of the one open wall. Think of this as the glampiest glamping you'll ever do and you will not be disappointed. Read the web site and reviews thoroughly and you won't be surprised. Being good hiking shoes, a lightweight waterproof jacket, refillable water bottle, a hat, binoculars (you can rent them too), bug spray, and sunscreen. Lightweight long sleeved shirts and long pants are essential bc you want to be covered so you won't get bitten or in case you brush up against a nasty plant. We saw monkeys, macaws, capybaras, owls, a caiman, and some cool jungle bugs. The guides even have a telescope you can use to both look at the animals and take great pictures with your phone. once in a lifetime experience in one of the most special and precious ecosystems in the world. Worth every penny and honestly we felt the price was cheap considering what you get. The highlight of our trip to Peru. Thank you so much. Read all

It was our first time in the rainforest and we wouldn't do it any other way. The boat rides on the Madre de Dios and the walks through the rainforests were both exciting and peaceful. Exciting when we spotted wildlife and peaceful as we settled in to hear the sounds and sights of the forest. The lodge was comfortable and the food was great. The research talks in the evenings were a great pre-dinner ritual for us. Do check them out. Saul was an amazing guide - friendly, fun, knowledgeable and very tuned to the rainforest. He could pick up on slight sounds and movements and helped us spot some great wildlife. Read all

TRC is up close with nature deep inside the Peruvian Amazon. If you are a fan of wildlife and love being in the nature t his is the place for you. This is an eco lodge, so come with similar expectations. The sound of macaws flying over would make your day. TRC is doing some amazing work on Macaw conservation, the visits to the clay lick would be special. During your journey you would be able to spot a number of animals, birds. Do not miss the guided walks, you would really see a lot of monkeys. If you are a photographer, invest in a good zoom lens ( it will pay you back). The other thing is the amazing staff that take care of you. The food is among the very best I tasted in Peru and they really pamper you. So make sure you walk a lot to burn the additional calories 🙂 Starting from the booking to the pickup in the airport everything is meticulously planned. From Mariella of the booking team, Juan Carlos the guide and Tania, our manager in the hotel everyone was fantastic. Ultimately spotting wild animals is a lot of luck, but this would be a great experience. Rooms: Rooms are large, spacious with wide open balconies, but no monkeys come in ( they strictly don't encourage wildlife feeding). Nearby activities: Lots of them, morning hikes, afternoon hikes, sunset cruise Walkability: You need to walk a bit, so you need to be mobile Food & drinks: Awesome Buffet, great food. Read all

TRC is up close with nature deep inside the Peruvian Amazon. If you are a fan of wildlife and love being in the nature t his is the place for you. This is an eco lodge, so come with similar expectations. The sound of macaws flying over would make your day. TRC is doing some amazing work on Macaw conservation, the visits to the clay lick would be special. During your journey you would be able to spot a number of animals, birds. Do not miss the guided walks, you would really see a lot of monkeys. If you are a photographer, invest in a good zoom lens ( it will pay you back). The other thing is the amazing staff that take care of you. The food is among the very best I tasted in Peru and they really pamper you. So make sure you walk a lot to burn the additional calories 🙂 Starting from the booking to the pickup in the airport everything is meticulously planned. From Mariella of the booking team, Juan Carlos the guide and Tania, our manager in the hotel everyone was fantastic. Ultimately spotting wild animals is a lot of luck, but this would be a great experience. Read all

The immersion experience was great. Be prepared though to feel hot and full of bug spray much of the time. Wear hiking p ants. Not Lulu leggings (too hot). The guides are great and you can do as much or as little as you want. We saw a lot of animals. Read all

Posadas Amazonas is an eco-friendly lodge that makes a huge commitment to preserving the rainforest for generations to c ome. The food served (breakfast, lunch and dinner) is fresh and delicious! The staff is extremely knowledgeable and caring. A special shoutout to the lodge manager Cesar for ensuring that we had packed meals for the onward journey when we were delayed by a rain storm. The main attractions apart from the abundant wildlife are the canopy tower and nearby Oxbow lake. The canopy tower gives a great 360 degree view of the rainforest and we were fortunate to see monkeys and macaws from the vantage point. At the Oxbow lake we saw river otters and Caimans and we were able to catch a piranha fish as well. Overall, Posada Amazonas is a great lodge owned and operated by the native communities located in the amazing Amazon rainforest. Read all

I had an amazing time here. I was traveling solo and did 4 days/3 nights through Inca Expert Travel. It was an unforgett able experience! I opted for a group tour for the excursions and am glad I did. Our guide, Boris, was fantastic and made sure we saw as much wildlife as possible. I can't say enough good things about him. The rest of the staff were also very kind. I enjoyed the large variety of fresh food at each meal. I felt safe and well-taken care of the entire time. Read all

TRC was an amazing place to stay. Being in the Amazon rainforest was truly like no other trip I have or will ever take. From arrival we were greeted by staff with cool drinks, warm welcomes. Beautiful main area w bar, sofas, tables,games. Our guide Fernando was SO knowledgeable, interesting, enthusiastic,. We already miss his smile and laugh 🙂 We did every excursion available over our 4 days there. The night hike turned out to be our favorite as we spotted the wandering spider then and many other intersting moths/insects. January is hot and humid, so yes expect to be wet,sweaty. Pack extra bag for wet stinky clothes ... Be ok w insects as no 4th wall in your rooms so at night mosquitio nets do a good job preventing bugs in your bed but when you wake up to use bathroom excpect moths, grasshopppers etc in room. All harmless!! TRC does provide nice rainboots for wet swampy treks.. Read all

A perfect experience in the Amazon. Harry, our guide, made the entire experience very memorable. The food is good, the b ar is expensive but good and the support staff were excellent. Tanya, the manager, took care of all our needs and was very supportive the entire stay. Please remember that the rooms are open to the nature and therefore comes with its pros and cons. You wake up with the nature including the mosquitos 🙂 The experiences offered by the Refugio is fantastic and provides a great exposure to the Amazon. Dont miss the Macaw trip. It is just magical. Read all

This is a once-in-a-lifetime experience! From the getgo, it was easy to coordinate our 4-day stay at Tambopata. The book ing was all done via email with quick responses, there was clear communication leading up to our stay and even upon arrival the staff was extremely organized (incl. taking our bags and making sure they arrived to our rooms). During our stay the staff was all very friendly and accomodating, the lodge was always clean (actually impressively clean given it is located in the jungle), and the food was great and plentiful. By far the best part of our stay was our tour guide, Saul. Upon arrival, Saul helped us pick our activities based on what animals we wanted to see (using his 10 years of experience). He worked on timing to make sure we can see as much as possible, was extremely knowledgable on the rainforest, the plants, the insects and the animals and noticeably put in the extra effort to find animals. You can tell that he truly loves his job and was always equally as excited to see the animals as us, even though he has seen them thousands of times. He helped us find monkeys, birds, countless insects, lizards, capybaras ect. I am 100% confident our experience wouldn't be the same without him. He even helped us capture these cool photos with only our iphone!! If you are planning to stay are TRC, I would highly recommend asking for Saul as a tour guide, if possible. Read all

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What Do Brazilian Wandering Spiders Eat?

The Brazilian wandering spider, also known as the banana spider or armed spider, is one of the most venomous spiders on the planet. While its venom is extremely potent, it isn’t as deadly as its five comparable species. Among these, the Australian funnel-web spider and the sand spider are also incredibly venomous. Despite its name, you won’t find this deadly spider eating bananas.

You may have heard that Brazil’s wandering spiders eat bananas, but a more common sighting is a tarantula in a banana. This large, brownish spider is not dangerous to humans, but is often mistaken for the deadly black tarantula. The spider’s egg sacs are often found inside bananas. While it’s rare for these spiders to actually bite people, they are still an annoyance.

Although the size of the Brazilian wandering spider isn’t very large, it does grow quite large and can be dangerous. Many years ago, these large spiders were transported to Europe in bananas. Today, bananas are consumed in Brazil almost exclusively. Because of this, large spiders are unlikely to be imported out of the country in banana shipments. If you happen to find a Brazilian wandering spider in a banana, you should be able to identify it fairly easily.

Unlike most species of spiders, Brazilian wandering spiders do not spin webs; instead, they swoop down on their prey. Their diets vary from large insects to small lizards. Spiderlings eat flightless fruit flies and newborn crickets. They only use spinnerets during egg sac production. When threatened, males must retreat rapidly. The wet bite from a wandering spider is deadly, and a wet one can kill a human in just two hours.

The nine species of Brazilian wandering spiders live in Brazil, with some species also found in Central and South America. These spiders are sometimes mistaken for harmless banana spiders when shipped to North America. In fact, this species is considered one of the most dangerous spiders. Despite the size, they are extremely poisonous and should not be handled lightly. Their bite can be deadly if not treated immediately. Phoneutria fera is one of the most dangerous Brazilian wandering spider species, as it has a venom potency sufficient to kill five people.

Other spiders

The Brazilian wandering spider is a dangerous, poisonous species. While it is rare to find one in the UK, it is common in South American rainforests. At night, it migrates across the jungle floor, preying on other spiders and other animals. Despite the deadly bite, the Brazilian wandering spider is not the deadliest or venomous spider. Here are some facts about them.

The genus Phoneutria is made up of several species, mostly found in tropical South and Central America. Members of this genus are commonly referred to as “banana spiders,” “armed spiders,” and “brazilian wandering spiders.” These spiders have distinct threat displays, which include clutching the ground as if to fight. If you are bitten by a Brazilian wandering spider, get medical attention right away. Fortunately, most cases can be treated fairly quickly, without severe complications.

Brazilian wandering spiders are known for their aggressive behavior and toxic bite. They attack only when provoked, and the bite is accompanied by goosebumps, sweating, and chills. A Brazilian wandering spider bite can cause severe pain, goose bumps, or even shock. In severe cases, the spider may even inflict convulsions. If you happen to accidentally injure a wandering spider, seek medical attention right away.

Venom from this spider has high potency and is effective against many vertebrate species. Scientists are investigating its venom, which contains the compound PnTx2-6. This compound blocks calcium entry and messes with brain function. Ultimately, it wrecks havoc on its prey. The venom of Brazilian wandering spiders kills mice in one bite. This arachnid is the “Deadliest Spider in the World.”

Small amphibians

The Brazilian wandering spider is an arachnid in the genus Phoneutria. The name “phoneutria” comes from the Greek word for murderress. This spider is considered to be one of the most venomous spiders on the planet. Their bite is extremely painful and can cause heavy sweating, drooling, skin swelling, redness, and heat. The spider is often called a “murderess” due to the fact that it can induce local piloerection.

There are several species of Brazilian wandering spiders, but two species are the most commonly reported worldwide. The spiders sometimes wander into cities and towns as well as fruit shipments. If you find one of these spiders in your home, seek medical attention as soon as possible to prevent serious injury. Among its diet are insects, other spiders, small mammals, amphibians, and reptiles. However, they are not poisonous to humans.

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Holistic profiling of the venom from the Brazilian wandering spider Phoneutria nigriventer by combining high-throughput ion channel screens with venomics

F. c. cardoso.

1 Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia

2 Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Australia

A. A. Walker

M. v. gomez.

3 Department of Neurotransmitters, Institute of Education and Research, Santa Casa, Belo Horizonte, Brazil

Rodrigo Ligabue-Braun , Federal University of Health Sciences of Porto Alegre, Brazil

Luiza Gremski , Federal University of Paraná, Brazil

Associated Data

The datasets presented in this study can be found in online repositories. The name of the repository and accession number are ProteomeXchange PRIDE repository; PXD037904.

Introduction: Spider venoms are a unique source of bioactive peptides, many of which display remarkable biological stability and neuroactivity. Phoneutria nigriventer , often referred to as the Brazilian wandering spider, banana spider or “armed” spider, is endemic to South America and amongst the most dangerous venomous spiders in the world. There are 4,000 envenomation accidents with P. nigriventer each year in Brazil, which can lead to symptoms including priapism, hypertension, blurred vision, sweating, and vomiting. In addition to its clinical relevance, P. nigriventer venom contains peptides that provide therapeutic effects in a range of disease models.

Methods: In this study, we explored the neuroactivity and molecular diversity of P. nigriventer venom using fractionation-guided high-throughput cellular assays coupled to proteomics and multi-pharmacology activity to broaden the knowledge about this venom and its therapeutic potential and provide a proof-of-concept for an investigative pipeline to study spider-venom derived neuroactive peptides. We coupled proteomics with ion channel assays using a neuroblastoma cell line to identify venom compounds that modulate the activity of voltage-gated sodium and calcium channels, as well as the nicotinic acetylcholine receptor.

Results: Our data revealed that P. nigriventer venom is highly complex compared to other neurotoxin-rich venoms and contains potent modulators of voltage-gated ion channels which were classified into four families of neuroactive peptides based on their activity and structures. In addition to the reported P. nigriventer neuroactive peptides, we identified at least 27 novel cysteine-rich venom peptides for which their activity and molecular target remains to be determined.

Discussion: Our findings provide a platform for studying the bioactivity of known and novel neuroactive components in the venom of P. nigriventer and other spiders and suggest that our discovery pipeline can be used to identify ion channel-targeting venom peptides with potential as pharmacological tools and to drug leads.

Introduction

Venomous animals are a highly adapted group of organisms whose evolutionary success excelled with the emergence of venom. Spider venoms, in particular, are rich in peptide knottins specialized in modulating, often with high potency and selectivity, voltage-gated ion channels that regulate the physiology of neuronal, muscular and cardiac systems ( Cardoso and Lewis, 2018 ; Cardoso, 2020 ). Although such effects can be deleterious to envenomated animals, venom components can be tailored to selectively modulate ion channels in pathways of complex diseases such as chronic pain, motor neuron disease, and epilepsy. This has been demonstrated for numerous spider venoms ( Smith et al., 2015 ; Cardoso and Lewis, 2018 , 2019 ), including the venom of the infamous South American ctenid spider Phoneutria nigriventer , often referred as Brazilian wandering spider, banana spider or “armed” spider ( Peigneur et al., 2018 ). Besides its clinical relevance due to frequent envenomation cases in Brazil, with approximately 4,000 cases per year ( Isbister and Fan, 2011 ; Gewehr et al., 2013 ), P. nigriventer venom contains peptides that have therapeutic effects in a range of disease models including chronic pain ( Pedron et al., 2021 ; Cavalli et al., 2022 ), Huntington’s disease ( Joviano-Santos et al., 2022 ), glaucoma ( da Silva et al., 2020 ) and erectile dysfunction ( Nunes da Silva et al., 2019 ).

Initial studies of P. nigriventer venom employed fractionation via gel filtration and reversed-phase chromatography to separate the venom into five distinct groups of peptides based on their molecular weight and hydrophobicity properties; these groups were named PhTx1 to PhTx5 ( Peigneur et al., 2018 ). PhTx1–4 comprise cysteine-rich peptides that are active on voltage-gated calcium (Ca V ), sodium (Na V ) and potassium (K V ) channels, while PhTx5 is comprised of short linear peptides, with a total of 34 peptides identified ( Peigneur et al., 2018 ). Proteotranscriptomic studies of P. nigriventer venom revealed additional peptides with high similarity to those previously described, but very few have been characterised pharmacologically ( Cardoso et al., 2003 ; Richardson et al., 2006 ). This represents an obstacle to the exploration of the therapeutic potential of P. nigriventer venom.

Advances in venom-peptide research have yielded high-throughput cellular screens for the discovery and pharmacological characterisation of naturally occurring molecules with activity at ion channels and receptors in physiological pathways ( Cardoso et al., 2015 ; Cardoso et al., 2021 ). These methods require only a small amount of venom compared to more traditional methods and allow the identification of therapeutically relevant peptides in the early stages of the screening. Besides drug development applications, these same bioassays can assist in unravelling the bioactivity of crude and fractionated venoms from biomedically relevant venomous animals to support studies of evolution and antivenom development, but much work remains to be done in this field.

This study aimed to provide a proof-of-concept in applying high-throughput cellular screens for multiple neuronal ion channels along with proteomic studies of fractionated venom to rapidly characterise spider venoms in terms of bioactive components. It was anticipated that such a pipeline would support envenomation and evolutionary studies and the development of therapeutics from animal venoms. The venom of P. nigriventer was selected as a model system due to its medical relevance, the considerable number of therapeutically relevant peptides already uncovered in the venom, and the wide knowledge base available. Our approach enabled identification of potent modulators of voltage-gated ion channels which were classified into four families of neuroactive peptides based on their activity and structures. In addition to the previously characterised neuroactive peptides in the P. nigriventer venom, we identified 27 additional cysteine-rich venom peptides in which neuroactivities are underexplored. This work contributes to the on-going discovery and structure-function characterisation of spider-venom peptides. Moreover, our bioassay pipeline can be used to guide future research into the discovery of venom peptides that modulate the activity of ion channels, and their development as pharmacological tools and drug leads.

Materials and methods

We applied a holistic approach combining methods in high throughput screens for ion channels, venom proteome, venom gland transcriptome and modelling of peptides as described in Figure 1 .

Flowchart of the venom peptide discovery pipeline applied in this study. Expanding from the traditional assay-guided fractionation, we applied HTS bioassays to characterize the pharmacology of venom peptides on multiple ion channels, followed by the identification of peptide masses and primary sequences using proteome and transcriptome. Ultimately, the three-dimensional structure of venom peptides was determined using in silico molecular modelling.

Cell culture

The human neuroblastoma cell line SH-SY5Y was maintained at 37 ° C in a humidified 5% CO 2 incubator in Roswell Park Memorial Institute (RPMI) medium supplemented with 15% foetal bovine serum (FBS) and 2 mM L-glutamine. Replicating cells were sub-cultured every 3–4 days in a 1:5 ratio using 0.25% trypsin/EDTA.

Venom fractionation

Crude venom milked from male and female specimens of P. nigriventer was kindly provided by Prof. Marcus Vinicius Gomez from the Institute of Teaching and Research of Santa Casa de Belo Horizonte, Belo Horizonte, Brazil. Venom (lyophilised, 1 mg) was dissolved in 100 μL Milli-Q water containing 0.05% trifluoroacetic acid (TFA) (Auspep, VIC, AU) and 5% acetonitrile (ACN) and centrifuged at 5,000 × g for 10 min to remove particulates. Venom was fractionated by reversed-phase high performance liquid chromatography (RP-HPLC) using a C18 column (Vydac 4.6 mm × 250 mm, 5 μm, Grace Discovery Sciences, United States) with a gradient of solvent B (90% ACN in 0.045% TFA) in solvent A (0.05% TFA). The gradient was 5% B for 5 min, followed by 20%–40% solvent B over 60 min at a flow rate 0.7 mL min −1 . Peaks were collected every minute, with fraction 1 eluted between 1 and 2 min and so on for the other fractions. Venom fractions were lyophilised before storage at –20°C.

Calcium influx assays

Venom fractions were screened for neuroactivity at human (h) Na V , Ca V 1, Ca V 2 and the α7 subtype of the human nicotinic acetylcholine receptor (nAChR-α7) as previously described ( Cardoso et al., 2015 ). Briefly, SH-SY5Y cells were plated at 40,000 cells per well in 384-well flat clear-bottom black plates (Corning, NY, United States) and cultured at 37 ° C in a humidified 5% CO 2 incubator for 48 h. Cells were loaded with 20 μL per well Calcium 4 dye (Molecular Devices) reconstituted in assay buffer containing (in mM) 140 NaCl, 11.5 glucose, 5.9 KCl, 1.4 MgCl 2 , 1.2 NaH 2 PO 4 , 5 NaHCO 3 , 1.8 CaCl 2 and 10 HEPES pH 7.4 and incubated for 30 min at 37 ° C in a humidified 5% CO 2 incubator. For the hCa V 1 assay, the dye was supplemented with 1 μM ω-conotoxin-CVIF (CVIF) to inhibit Ca V 2, and in the hCav2 assay the dye was supplemented with 10 μM nifedipine to inhibit Ca V 1. For the nAChR-α7 assay, the dye was supplemented with PNU-120596 (Sigma-Aldrich), a positive allosteric modulator of nAChR-α7. Venom fractions were assayed in singleton for each ion channel tested. Fluorescence responses were recorded using excitation at 470–495 nm and emission at 515–575 nm for 10 s to set the baseline, then 300 s after addition of 10% venom fraction serial diluted at 1, 1:10, and 1:100, and for a further 300 s after addition of 50 μM veratridine for hNa V , 90 mM KCl and 5 mM CaCl 2 for hCa V, and 30 μM choline for nAChR-α7.

Venom fractions eluting between 10 and 45 min on RP-HPLC were analysed by mass spectrometry to investigate the masses and primary structures of their peptide components. Native mass determinations were carried out with 20% of each fraction dried by vacuum centrifuge and resuspended in 20 μL 1% formic acid (FA), followed by analysis using by liquid chromatography/tandem mass spectrometry (LC-MS/MS). For identification of primary structures, 20% of each peptide fraction was reduced and alkylated by adding 40 μL of reagent composed of 4.875 mL ACN, 4.5 mL ultrapure water, 0.5 mL 1M ammonium carbonate pH 11.0, 100 μL 2-iodoethanol and 25 μL triethylphosphine, and incubating for 1 h at 37°C. Samples were speed dried in a vacuum centrifuge, and digested with 40 ng/μL trypsin in 50 mM ammonium bicarbonate pH 8.0 and 10% ACN overnight at room temperature. Trypsin was inactivated by adding 50 μL solution containing 50% acetonitrile and 5% formic acid (FA), dried in speed vacuum centrifuge, and resuspended in 1% formic acid.

LC-MS/MS samples were loaded onto a 150 mm × 0.1 mm Zorbax 300SB-C18 column (Agilent, Santa Clara, CA, United States) on a Shimadzu Nano LC system with the outflow coupled to a SCIEX 5600 Triple TOF (Framingham, MA, United States) mass spectrometer equipped with a Turbo V ion source. Peptides were eluted using a 30 min gradient of 1%–40% solvent B (90% ACN/0.1% FA) in solvent A (0.1% FA) at a flow rate of 0.2 mL/min. For MS1 scans, m/z was set between 350 and 2,200. Precursor ions with m/z 350–1,500, charge of +2 to +5, and signals with >100 counts/s (excluding isotopes within 2 Da) were selected for fragmentation, and MS2 scans were collected over a range of 80–1,500 m /z . Scans were obtained with an accumulation time of 250 ms and a cycle of 4 s.

A database of possible peptide sequences produced in P. nigriventer venom glands was compiled using a published venom-gland transcriptome ( Diniz et al., 2018 ), from which open reading frames (ORFs) longer than 30 amino acids were identified and translated by TransDecoder. A list of 200 common MS contaminants was added to the translated ORFs, which was used as a sequence database to compare to mass spectral data using the Paragon algorithm in Protein Pilot 2.2 software (AB SCIEX). We report only peptides for which more than two tryptic fragments were detected with >95% confidence, or where one tryptic fragment was detected, and a secretion signal peptide was predicted by SignalP5.0.

Molecular modelling

Venom peptides identified in this study were selected based on their cysteine-rich scaffold and bioactivity, and their three-dimensional (3D) structure were predicted using the AlphaFold 2 algorithm ( Jumper et al., 2021 ). All 3D structures displayed were from unrelaxed models ranked 1 for each peptide prediction. 3D structures were visualised and analysed using PyMol ( Pymol, 2023 ).

Data analysis

Fluorescence traces from singletons were evaluated using the Maximum-Minimum or Area Under the Curve values generated after addition of ion channel activator. Data were normalised against the negative control (PSS buffer control) and positive control (ion channel activator) for each assay and corrected using the response over baseline from 1 to 5 s. No statistical analyses were required in this study.

Screening of P. nigriventer venom fractions

Fractionation of 1 mg of P. nigriventer ( Figure 2A ) crude venom using RP-HPLC produced numerous peaks eluting between 20% and 40% solvent B, and fractions eluting between 11 and 45 min were selected for pharmacological analysis ( Figure 2B ). Screening using the SH-SY5Y neuroblastoma cell line revealed strong modulation of voltage-gated ion channels including both inhibition or enhancement of ion channel activity ( Figure 2C ). Venom fractions eluting between 18 and 34 min showed strong inhibition of Ca V and Na V activity, while fractions eluting between 41 and 45 min strongly activated Ca V 2 channels ( Figure 2C , top panel). At a dilution of 1:10, these inhibitory effects persisted for both Na V and Ca V 2 channels for fractions eluting at 19–20 min and 26–34 min and was absent for Ca V 1 channels ( Figure 2C , middle panel). Fractions eluting from 21 to 25 min showed a clear preference for inhibiting only Ca V 2 channels ( Figure 2C ). Interestingly, at 1:10 dilution, channel activity enhancement was stronger on Na V channels compared to Ca V 2 channels, suggesting potential concentration-dependent synergistic effects of venom peptides modulating both Na V and Ca V 2 channels. At the highest venom dilution of 1:100, persistent inhibition of Na V channel was observed for fraction 20 (F20), while the remaining inhibitory fractions preferentially inhibited only Ca V 2 channels ( Figure 2C , bottom panel). Channel enhancement persisted for Na V channels in fractions eluting from 41 to 45 min. No potent activity was observed against nAChR-α7 at any venom concentration tested. Overall, inhibitory activity was primarily observed for fractions eluting at shorter retention times (i.e., more hydrophilic compounds), while strong ion channel activation was induced by more hydrophobic peptides with longer RP-HPLC retention times.

Fractionation and activity of P. nigriventer venom. (A) P. nigriventer specimen displaying threat posture (photo copyright Alan Henderson, www.minibeastwildlife.com.au ). (B) RP-HPLC fractionation of 1 mg P. nigriventer venom. (C) Ion channel responses calculated from the area under the curve (AUC) after addition of selective activators for fractions 10 to 45, normalized to responses in the absence of venom fractions. (D, E) Representative fluorescence traces of the intracellular calcium responses of SH-SY5Y cells evoked by KCl + CaCl 2 in the presence of venom fractions 26 and 34 for Ca V 1, fractions 19, 26 and 34 for Ca V 2, and fractions 41–45 for both Ca V 1 and Ca V 2 channels. (F) Representative fluorescence traces of the intracellular calcium responses of SH-SY5Y cells evoked by veratridine and in the presence of venom fractions 19, 26 and 34 and fractions 41–45. (G) Representative fluorescence traces of the intracellular calcium responses of SH-SY5Y cells evoked by choline and in the presence of venom fractions 16 and 40 and fractions 41–45. Grey dotted line indicates the KCl + CaCl 2 , veratridine or choline addition.

Fluorescent traces measured upon addition of venom fractions revealed an increase in intracellular calcium ([Ca 2+ ] i ), suggesting that these venom peptides can activate closed channels as well as enhance the responses of these channels opened using pharmacological intervention ( Figures 2D–G ). This was observed for Ca V responses in the presence of 1 μM CVIF (Ca V 2 inhibitor, Figure 2D ) and 10 μM nifedipine (Ca V 1 inhibitor, Figure 2E ). In the absence of Ca V inhibitors, these [Ca 2+ ] i responses resemble the levels of Ca V 1 responses in Figure 2D as observed for F40–F45 applied in the Na V channels assay ( Figure 2F ). The activities of inhibitory fractions were mostly free from initial [Ca 2+ ] i responses upon venom addition, except for weak inhibitors observed in F19 for Na V and F40 for nAChR-α7 ( Figures 2F, G ).

Identification of peptides in P. nigriventer venom fractions

The venom of P. nigriventer has been extensively characterised in terms of composition and bioactivity ( Diniz et al., 2018 ; Peigneur et al., 2018 ), including neuronal ion channel activity and proteomics, but not by using a combined approach. In this study, by combining these approaches, we were able to rapidly identify 58 peptides and proteins in the venom. Due to the complexity of previous nomenclature for P. nigriventer venom peptides, we refer to them here using both the rational nomenclature developed for spider toxins ( King et al., 2008 ) and an identifying number (e.g., PN367) that is linked to a sequence and a list of previously used names in Supplementary Table S1 . Of the 58 identified amino acid sequences, only eight (15%) are peptides that have had their bioactivity reported in previous studies ( Figure 3A , Supplementary Table S1 ) ( Peigneur et al., 2018 ). These included the known neuroactive components μ-CNTX-Pn1a (Tx1) ( Diniz et al., 2006 ; Martin-Moutot et al., 2006 ), κ-CNTX-Pn1a (Tx3-1, PhK V ) ( Kushmerick et al., 1999 ; Almeida et al., 2011 ), ω-CNTX-Pn1a (Tx3-2) ( Cordeiro Mdo et al., 1993 ), Γ-CNTX-Pn1a [Tx4(5-5)] ( Paiva et al., 2016 ), δ-CNTX-Pn1a [Tx4(6-1)] ( de Lima et al., 2002 ; Emerich et al., 2016 ), δ-CNTX-Pn2c (Tx2-5a) ( Yonamine et al., 2004 ), ω-CNTX-Pn4a (Tx3-6) ( Cardoso et al., 2003 ; Vieira et al., 2005 ) and ω-CNTX Pn3a (Tx3-4) ( Dos Santos et al., 2002 ) ( Figure 3B ). Even among these eight peptides, only a few venom peptides have had their molecular pharmacology characterized in detail ( Peigneur et al., 2018 ), or their activities confirmed using recombinant peptides ( Diniz et al., 2006 ; Paiva et al., 2016 ; Garcia Mendes et al., 2021 ).

Estimated levels of peptide/protein venom components identified in fractions F17 to F45, and their respective bioactivity at Na V and Ca V channels and the nAChR-α7. (A) Proportion of known and unknown venom peptides and other venom components detected in this study. (B) Venom peptides with previously reported bioactivity detected in fractions by mass spectrometry and compared to fraction bioactivity at Na V and Ca V channels and the nAChR-α7. (C) Venom peptides detected in fractions classified according to their cysteine framework I to IX ( Diniz et al., 2018 ), and compared to fraction bioactivity at Na V and Ca V channels and the nAChR-α7.

Most of the identified sequences in this study (74%) represent peptides with unexplored bioactivity; 38 (65%) of the 43 peptides identified have cysteine-rich scaffolds typical of spider-venom peptides ( Figure 3C ). Some of these venom peptides, such as PN367 and PN363, have a type I scaffold ( Diniz et al., 2018 ) and are predicted by Alphafold 2 to fold into cystine-knot scaffolds typical of spider-venom peptides ( King and Hardy, 2013 ) ( Figure 4 ). Scaffolds II-VIII either form elaborated cystine-knot folds with extra disulphide bonds, or alternative structures such as for scaffolds III and IV ( Figure 4 ). Novel peptides with high identity with other toxins and not previously described in P. nigriventer venom included: PN367 displaying identity with a Agelena orientalis venom peptide; PN369 displaying identity with a Lycosa singoriensis venom peptide, and PN365 displaying scaffold III and identity with another Lycosa singoriensis venom peptide ( Supplementary Table S1 ). Additional disulphide-rich scaffolds present in P. nigriventer venom include three peptides predicted by the algorithm HMMER to form a thyroglobulin type 1 repeat domain (E < e −17 in each case), one of which has been previously reported as U24-CNTX-Pn1a; peptide PN370 which displays high identity with a peptide found in venom of the scorpion Scorpiops jendeki and is predicted by the algorithm HMMER to form into a trypsin-inhibitor-like cysteine-rich domain (E < 2e −13 ); and the peptide PN376 that is predicted by HMMER to form a fungal protease inhibitor domain (E < e −6 ) ( Supplementary Table S1 ). Additional new scaffolds identified in this study were named following the previous suggested nomenclature ( Diniz et al., 2018 ) as X (CXCC motif, 12 Cys residues: −C−C−C−C−CXCC−C−C−C−C−C−), XI (12 Cys residues: −C−C−C−CXC−CXC−C−CXC−C−C−), XII (11 Cys residues: −C−C−CXC−CXC−C−C−CXC−C) and XIII (10 Cys residues: −C−C−C−C−C−C−CXC−C−C−), and include the peptides PN376, PN372, PN373 and PN375, and PN370, respectively.

Diversity and estimated levels of cysteine-rich scaffolds identified in highly neuroactive RP-HPLC fractions from the venom of P. nigriventer , and their predicted 3D structures. (A) Fractions 18–20 comprised high levels of scaffolds I, II and VIII represented by the 3D structures of PN367, PN105 and PN267, respectively. (B) Fractions 26 and 27 comprised high levels of scaffolds II, and IV, and an undefined scaffold represented by the 3D structures of PN321, PN350 and PN372, respectively. (C) Fraction 34 comprised high levels of scaffolds I, II, and V represented by the 3D structures of PN003, PN292 and PN028, respectively. (D) Fractions 41 and 42 comprised high levels of scaffolds IV and V represented by the 3D structures of PN381, and PN077 and PN031, respectively.

Only 9% of the identified sequences were peptides with two or fewer Cys residues ( Supplementary Table S1 ). F17 contained a peptide (PN361) matching a C-terminally amidated peptide precursor from Araneus ventricosus identified in a genomic study ( Kono et al., 2019 ). This precursor has 70% sequence identify with the prohormone-1 like precursor from the honeybee Apis mellifera (UniProt {"type":"entrez-protein","attrs":{"text":"P85798","term_id":"190360036","term_text":"P85798"}} P85798 ) which is believed to be cleaved to form three short peptides with neuronal activity. Another short peptide, PN366 identified in F18 and F28–F30, matches a neuropeptide in the sea slug Aplysia californica (UniProt {"type":"entrez-protein","attrs":{"text":"P06518","term_id":"113518","term_text":"P06518"}} P06518 ). Larger proteins were also detected in some fractions; for example, F18 and F31 contained a fragment at 58% and 70% total fraction components, respectively, matching a zinc metalloprotease from the nematode Caenorhabditis elegans (UniProt 55112) which contains a peptidase family M12A domain.

Diversity of neuroactive peptides in P. nigriventer venom

The cysteine-rich scaffolds of venom peptides identified in this study were compared to the classification previously proposed for P. nigriventer venom peptides ( Diniz et al., 2018 ) ( Figures 3C , ​ ,4). 4 ). Peptides in fractions displaying inhibitory properties corresponded to scaffolds I, II, IV, V and VIII, as well as unnamed scaffolds, while peptides in fractions with activation properties comprised mostly the scaffold V. All of these scaffolds are inhibitor cystine knot motifs, except for scaffold IV which had the highest level in F26 represented by the peptide PN350.

Neuroactive peptides with greater hydrophilicity (i.e., those with short RP-HPLC retention times) showed pharmacological properties reminiscent of known spider-derived μ-toxins (F17 and F18) and ω-toxins (i.e., inhibition of Ca V 1 and Ca V 2 channels by F19 and F20) ( Figures 2C , ​ ,5A). 5A ). Major components driving those bioactivities were the pharmacologically characterised peptides μ-CNTX-Pn1a, ω-CNTX-Pn1a and ω-CNTX-Pn3a, as well as additional peptides with unknown activity ( Figure 4A ). As the hydrophilicity of the peptides decrease (i.e., peptides with long RP-HPLC retention times), persistent Ca V 2 inhibition was observed with maximum inhibitory activity in F26 and F27, and with the additional peptide ω-CNTX-Pn4a detected in F24 ( Figures 2C , ​ ,3B, 3B , ​ ,5B). 5B ). Interestingly, venom peptides characterized as K V modulators, such as κ-CNTX-Pn1a, were detected in fractions displaying strong inhibition of calcium influx with potential μ- and ω-pharmacology (fractions 26 and 27); it was not clear if the observed bioactivity was associated to the modulation of K V channels, or to other unexplored peptides in these fractions.

Venom peptide content of highly neuroactive RP-HPLC fractions from the venom of P. nigriventer . (A) Identification of the cysteine-rich peptides and proteins in fractions 17–20 displaying potent inhibition of neuronal Na V and Ca V 2 channels. Positively and negatively charged residues are coloured blue and orange, respectively, hydrophobic residues are green, and cysteines are highlighted in grey box. (B) Identification of the peptide and protein content of the fractions 16 and 27 displaying potent inhibition of neuronal Na V , Ca V 1 and Ca V 2 channels. (C) Identification of the peptide and protein content of the fraction 34 displaying potent inhibition of neuronal Na V , Ca V 1 and Ca V 2 channels. (D) Identification of the peptide and protein content of the fraction 34 displaying potent activation of neuronal Na V and Ca V 2 channels. Sequences labelled with a red asterisk (*) at the C-terminal are likely C-terminally amidated.

Neuroactive peptides presenting more hydrophobic structures showed properties of μ and ω-peptides, but with preference for Ca V 2 channels as observed for fraction 34 in which the peptide Γ-Pn1a is the major component, consistent with its previously observed modulation of multiple cation channels ( Paiva et al., 2016 ); and of δ-peptides as observed in fractions 41 to 45, in which major components included the peptides δ-Pn1a and δ-Pn2c ( Figures 2C–F , and Figures 5C, D ). Notably, the main components of some of the most neuroactive fractions are peptides with unexplored bioactivity, e.g., fraction 26 ( Figures 2C , ​ ,4, 4 , ​ ,5 5 ).

Pharmacological groups

Our approach allowed classification of P. nigriventer venom peptides into four major groups based on their bioactivity ( Figure 6 ; Table 1 ). Group 1 is comprised of μ and ω peptides with scaffold type VIII and more hydrophilic properties as they eluted between F17 and F21. As representatives from this group, μ-CNTX-Pn1a and ω-CNTX-Pn3a have a potential “KR electrostatic trap”, a pharmacophore described in spider-venom peptides that modulate ion channels ( Hu et al., 2021 ; Wisedchaisri et al., 2021 ), in their primary and tertiary structures ( Figure 6A ). This pharmacophore is likely composed of residues R61, K67, K70, K71, R74 and R75 in μ-CNTX-Pn1a and residues K54, K56, R59, K65, K70, R71, K73 and K74 in ω-CNTX-Pn3a. Within this group, the ω-CNTX-Pn3a homologue PN319 differs at three positions, making it an interesting candidate for further characterisation.

Pharmacological groups identified in the most active venom fractions highlighting the “KR electrostatic trap” pharmacophore common to spider toxins that modulate the activity of ion channels. (A) Group 1 is represented by μ- and ω-spider-venom peptides with large and complex type VIII scaffold. (B) Group 2 is represented by κ- and ω-spider-venom peptides with type II and VII scaffolds. (C) Group 3 is represented by γ-spider-venom peptides with type V scaffold. (D) Group 4 is represented by δ-spider-venom peptides displaying a type V scaffold. K and R residues located in the C-terminal region of these peptides and grouped on a positively charged face are highlighted in red in the sequences and in red tubes in the corresponding 3D structures. Arrows shows the cysteine-bridge connection forming the cyclic peptide structures predicted for PN028 and PN031.

Pharmacological groups identified in this study with respective pharmacological types, cysteine-rich scaffold types, and representative venom peptides described in the literature. Unexplored peptides within each group are described in Figure 5 and/or Supplementary Table S1 .

Group 2 comprises κ and ω peptides that eluted between F17 and F28, with scaffold types II and VII ( Figure 6B ). As representatives from this group, peptides κ-CNTX-Pn1a, ω-CNTX-Pn1a and ω-CNTX-Pn4a also contain a “KR trap” pharmacophore comprised of residues R20, K23, K34, K35 and K36 for ω-Pn1a; R21, K24, K35 and K36 for κ-Pn1a; and K42, R47, K48, K49, K51, K53 and K54 for ω-Pn4a. In this group, PN107 differs from κ-CNTX-Pn1a by only two residues and is an interesting peptide for further exploration.

Group 3 is comprised of more hydrophobic Γ peptides that eluted in F33–F36 and possess a type V scaffold ( Figures 3C–D , ​ ,6C). 6C ). It is represented by Γ-CNTX-Pn1a with a potential “KR trap” comprising residues K35, R41, K42 and K43. Although Γ peptides modulate N-methyl-D-aspartate (NMDA) glutamate receptors, Γ-CNTX-Pn1a has also been reported as a β-peptide that inhibits Na V channels ( Paiva et al., 2016 ), which agrees with the results from our high-throughput ion channels assays ( Figures 2C–F , ​ ,3). 3 ). Interestingly, Γ-CNTX-Pn1a predicted 3D structure formed a cyclic structure in which the N-terminal cysteine formed a disulfide bridge with C-terminal cysteine ( Figures 4C , ​ ,6C). 6C ). These same fractions contain other ICK peptides including PN003 and PN292 with scaffold types I and II, respectively; their pharmacological targets have not been explored but they likely contribute to the strong inhibition of Ca V channels by F34 ( Figures 2 , ​ ,3, 3 , ​ ,4 4 ).

Group 4 is composed of very hydrophobic δ peptides that elute in F40–F45 and possess a type V scaffold ( Figure 2B , ​ ,6D). 6D ). It is represented by δ-CNTX-Pn1a with potential “KR trap” comprising residues K43, K44, and K45 ( Figure 6D ). In this group we also identified δ-CNTX-Pn2c which differs not only in primary structure but also in the scaffold V tertiary structure by presenting a non-cyclic structure compared to the cyclic structure predicted for δ-CNTX-Pn1a connected by the N- and C-terminal cysteines ( Figures 4D , ​ ,6D). 6D ). Beyond these known peptides, this group comprised interesting unexplored peptides such as PN032 and PN023 showing δ peptide domains and differing from Γ-CNTX-Pn1a by 12 and 11 residues, respectively.

Spiders are one of the most speciose venomous taxa, with >50,000 characterised species (see World Spider Catalog, https://wsc.nmbe.ch/statistics/ ). Their venoms are rich in neuroactive peptides that target a wide range of neuronal ion channels and receptors using mechanisms distinct from those of neurotoxins from other venomous animals such as cone snails and scorpions. The exploration of venom peptides targeting ion channels and receptors provides novel opportunities for the development of pharmacological tools to understand disease mechanisms ( Cardoso and Lewis, 2018 ; Cardoso, 2020 ) as well as provision of leads for development of therapeutics ( King, 2011 ) and bioinsecticides ( Smith et al., 2013 ).

Spiders are classified in two major groups, or infraorders ( King, 2004 ): Mygalomorphae, or so-called “primitive spiders”, includes the family Theraphosidae, or tarantulas, which are the most well studied spider venoms due to the large-size and long lifespan (often >20 years) of these spiders. Araneomorphae, or “modern spiders,” comprise >90% of all extant spider species, including the family Ctenidae in which P. nigriventer resides. Notably, despite their much greater species diversity, araneomorph venoms are underexplored compared to mygalomorphs due to their smaller size and shorter lifespan (typically 1–2 years). Our data, and those of others ( Binford et al., 2009 ; Zhang et al., 2010 ; Diniz et al., 2018 ; Peigneur et al., 2018 ), showed a great diversity of both pharmacological actions and cysteine scaffolds in araneomorph venom, which may have facilitated the highly successful araneomorph radiation. Our data also suggests Araneomorphae’s venoms may be a rich source of unique venom peptides with more diverse structures and pharmacological functions and additional biotechnological and therapeutic applications to Mygalomorphae’s venoms.

The venom from P. nigriventer comprises many exceptional peptides drug leads under development for treating a range of complex neuro disorders ( Peigneur et al., 2018 ). These peptides have been evaluated in pre-clinical models and demonstrated interesting therapeutic efficacy in reverting or preventing conditions for which treatments are limited or unavailable. For example, ω-Pn2a and ω-Pn4a showed efficacy in treating painful neuropathies such as fibromyalgia and chronic post-ischemia pain, respectively ( Pedron et al., 2021 ; Cavalli et al., 2022 ), ω-Pn4a also improved motor movement and neuroprotection in Huntington’s disease ( Joviano-Santos et al., 2022 ). The engineered peptide PnPP-19 derived from the venom peptide δ-Pn2a was efficacious in treating glaucoma ( da Silva et al., 2020 ) and erectile dysfunction ( Nunes da Silva et al., 2019 ). In our study, these therapeutic peptides showed bioactivity at neuronal Na V and Ca V channels, which greatly supports our investigative platform for the discovery of venom peptides useful for the development of efficacious drugs.

Investigative pipelines in venomic studies often focus on the elucidation of venom components based on their structures but lack clear strategies to investigate venom bioactivities ( von Reumont et al., 2022 ). Investigations using fractionated venom ( Cardoso et al., 2015 ; Cardoso et al., 2017 ; Estrada-Gomez et al., 2019 ; Cardoso et al., 2021 ) provides more defined biological functions than using crude venom due to the immense pharmacological diversity of venom, which often contains venom components with opposing activity as well as components that act synergistically ( Raposo et al., 2016 ). Considering the large number of extant spiders and consequently the exceptionally large number of venom components available for investigation, high-throughput (HT) functional bioassays are essential for developing a holistic understanding of venom pharmacology, and they provide a complement to venomic studies.

A recent study by us using HT bioassays to investigate the ion channel targets of Australian funnel-web spider venoms recaptured current taxonomy and revealed potential drug targets to treat severely envenomated patients ( Cardoso et al., 2022 ). In this present study, we also demonstrated the feasibility of applying HT functional bioassays to investigate spider venom components that mediated the activity of voltage-gated ion channels. We were able to capture all known venom components and associated bioactivities using a HT functional assay as well as several new unexplored venom peptides that warrant further exploration. This was achievable only by combining HT bioassays with transcriptomic and proteomic approaches. Although this pipeline provides a robust holistic overview of spider venoms, bioactive components are present in varying concentrations in each fraction, which may affect bioactivity through synergistic effects, and overlook the activity of less abundant components.

The complexity of the cysteine-rich scaffolds in P. nigriventer venom peptides unraveled in this study suggests that further exploration utilising recombinant or synthetic peptides might be challenging but essential, and these could also benefit from modern strategies utilizing HT recombinant expression or chemical synthesis ( Pipkorn et al., 2002 ; Turchetto et al., 2017 ). In tandem with automated whole-cell patch-clamp electrophysiological studies, this will build a pipeline to further investigate known and new peptides in the venom of P. nigriventer and allow selection of candidates with biotechnological potential. The putative “KR trap” pharmacophores identified in those venom peptides warrants further exploration of the structure-function relationships of the diverse pharmacological groups found in the venom of P. nigriventer.

In conclusion, we demonstrated that the introduction of HT functional bioassays in venomic studies is essential to provide a more complete understanding of venom components in terms of structure and function. It also allows venom peptides to be ranked for further investigation based on their bioactivity and structural diversity, which is not possible via transcriptomic and proteomic studies alone. Furthermore, this study provides a guide to assist the exploration of neuroactive venoms from other animals, in particularly for the underexplored araneomorph spiders.

Acknowledgments

We thank Mr. Alun Jones and Dr. Kuok Yap (Institute for Molecular Bioscience, The University of Queensland) for assistance with mass spectrometry experiments.

Funding Statement

This work was supported by The University of Queensland, the Australian National Health and Medical Research Council (Ideas Grant GNT1188959 to FC; Principal Research Fellowship APP1136889 to GK), and the Australian Research Council (Discovery Grant DP200102867 to AW; Centre of Excellence Grant CE200100012 to GK).

Data availability statement

Author contributions.

Conceptualization: FC; design, conduct, and analysis of experiments: FC and AW; MG contributed with the P. nigriventer crude venom. drafting of manuscript: FC. All authors contributed to reviewing and editing of the manuscript and approved the final version for submission.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Supplementary material

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1069764/full#supplementary-material

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Brazilian Wandering Spider size: how big do they get?

As an avid arachnid enthusiast, my fascination with these eight-legged creatures knows no bounds. There’s something utterly captivating about their intricate web-weaving capabilities, their exceptional survival strategies, and of course, their range of sizes and appearances. But amongst this vast collection of species, one has particularly piqued my interest – the Brazilian Wandering Spider.

Arguably one of the most notorious names in the world of arachnids, the Brazilian Wandering Spider, holds a firm position at the pinnacle of spider folklore. Their reputation extends far beyond their native tropical South American rainforests, captivating the minds of arachnologists and laymen alike around the globe.

What sets this spider apart in the arachnid world? It’s not just its venomous nature – it’s also its astonishing size. The dimensions of the Brazilian Wandering Spider are a spectacle in themselves.

How big are Brazilian Wandering Spiders?

Picture this: a spider so large that it could comfortably cover an average dinner plate. That’s right – the Brazilian Wandering Spider can grow to an impressive leg span of up to 7 inches , or approximately 18 cm, with females tending to be larger than the males.

To put this into perspective, that’s around half the size of an average adult human’s face! The body length of these spiders can reach up to 2 inches, or around 5 cm. This considerable size, coupled with their highly potent venom, makes them a formidable presence in their habitats.

But as an arachnid hobbyist, the allure of the Brazilian Wandering Spider’s size lies not in its potential threat, but in the fascinating evolutionary adaptations that have allowed it to grow to such an impressive scale.

The advantage of large size for a cursorial hunter

From an evolutionary standpoint, the Brazilian Wandering Spider’s significant size offers multiple advantages. For starters, their considerable size allows them to subdue and consume a larger variety of prey, including insects, other spiders, and sometimes even small amphibians and reptiles. This dietary diversity is a testament to their adaptability and survival prowess.

However, the size of these spiders is not solely an indicator of their hunting prowess. It also reveals a fascinating aspect of their biology. The Brazilian Wandering Spider, unlike some smaller spider species, does not weave a web to capture its prey. Instead, as their name suggests, they wander in search of food, relying on their size and strength to overpower their prey. This is called cursorial hunting .

Their size also plays a crucial role in their mating rituals. Male Brazilian Wandering Spiders, despite being smaller than their female counterparts, engage in a daring dance of danger during mating. They utilize their size and strength to lift the larger female’s body to prevent her from eating him – a gruesome but prevalent behavior known as sexual cannibalism in the arachnid world.

Size relates to the biology of the Wandering Spider

The Brazilian Wandering Spider’s size, therefore, is much more than just an intimidating factor. It’s a key to understanding their hunting methods, their mating rituals, and their overall survival strategy. Each inch adds to the mystique of these extraordinary creatures and deepens our understanding of the diverse world of arachnids.

The Brazilian Wandering Spider is undeniably a creature of fascination. From its substantial size to its potent venom, it’s a spider that demands respect. Whether you’re an arachnid hobbyist like me, or just someone intrigued by the wonders of the natural world, the Brazilian Wandering Spider offers a fascinating insight into the awe-inspiring world of arachnids.

Final thoughts…

In conclusion, the world of spiders is as vast and varied as the creatures themselves. The Brazilian Wandering Spider, with its impressive size, offers a fascinating window into this world. It’s a testament to the incredible diversity of life on Earth and a reminder of the intricate balance that governs our ecosystems.

My fascination with spiders continues to grow, much like the impressive size of the Brazilian Wandering Spider. And while their size may be a source of fear for some, for me, it only fuels my passion and curiosity about these fascinating creatures. After all, understanding is the first step to appreciation, and these giant spiders deserve nothing less.

Whether you’re a fellow arachnid enthusiast or just passing by, I hope this deep-dive into the size of the Brazilian Wandering Spider has sparked your curiosity. So the next time you hear about this giant spider, remember, there’s more to its size than meets the eye!

If you’d like to learn more about these spiders, check out my article on Brazilian Wandering Spider facts .

FAQ related to Brazilian Wandering Spider Size

How bad is a brazilian wandering spider bite.

A Brazilian Wandering Spider bite is considered a medical emergency. If you have a suspected or confirmed bite, your first move should be to contact the emergency services. Upon reaching you, they will determine whether to administer antivenom, and how to proceed with treatment. Fortunately, deaths are very rare, and the antivenom is widely available in South America.

Is a banana spider the same as a Brazilian wandering spider?

The common name of “Banana Spider” is used for a few species, not just the Brazilian Wandering Spider. For example, the Golden Silk Orb Weaver is often referred to as a banana spider, despite being completely unrelated. If you wish to find out if a spider is venomous, always rely on its scientific, or binomial name, rather than common names.

Where do Brazilian wandering spiders hide?

Brazilian Wandering Spiders are nocturnal hunters, and generally prefer to shy away from daylight. This means they often hide in the shadiest places they can find, either indoors or outdoors. For example, under a log or in leaf litter would be a perfect place outdoors. Indoors, they will try to hid behind or under furniture, or in dark corners.

What is the world’s biggest Brazilian wandering spider?

There are around 40 species of Wandering Spider, but the largest, and most infamous are those that we call the Brazilian Wandering Spider. This name is in fact commonly ascribed to two species: Phoneutria nigriventer and Phoneutria fera. Both of these spiders can reach at least 6 inches (15cm) in legspan.

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