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The 7 best mississippi river cruises for 2024.

Explore the history, culture and cuisine of the U.S. while cruising along the Mighty Mississippi.

The Best Mississippi River Cruises

Courtesy of American Cruise Lines

The more than 2,300-mile Mississippi River invites travelers to discover its multifaceted heritage, with a vast range of deeply rooted culture, music and history. A cruise is a fantastic way to discover many of the riverfront cities on a single trip, from the comfort of your modern riverboat or traditional paddle-wheeler.

The following Mississippi River cruise itineraries can help you choose from cruises of various lengths and options for the Lower and Upper Mississippi. Note that all fares are listed as double occupancy (based on two people per cabin), and that they might not reflect taxes, port fees or gratuities. The itinerary availability listed is also subject to change.

American Cruise Lines

Courtesy of American Cruise Lines | www.AmericanCruiseLines.com

American Cruise Lines operates small ships accommodating between 90 and 180 passengers that are built, flagged and crewed in the U.S. – and it's the only company in the world operating a 100% U.S.-flagged fleet of riverboats and cruise ships. ACL's itineraries traverse waterways across 35 states, with 11 itineraries dedicated to the Mississippi River. Cruisers can choose to sail on modern riverboats with a sleek interior design or while away their time aboard classic paddle-wheelers reminiscent of days gone by.

ACL offers variety as well as versatility: This line boasts both the longest and shortest sailings on this list with cruises ranging from eight to 60 days in length, including The Great United States. This inaugural 60-day voyage spans four major rivers and 20 states, making it the longest U.S. river cruise in history.

Complimentary hotel and transportation packages are available from every departure city before your cruise. You can book certain premium packages for added perks, such as two nights spent next door to Graceland in Memphis – with VIP tickets and a city tour included in the price.

Music Cities Cruise

Length: Eight days Price: Starts at $3,610 per person

Spend a week getting lost in the sounds of the Memphis blues, rock 'n' roll and country music legends on the seven-night Music Cities Cruise. A hotel stay the night before your sailing is included, but embarking in Memphis means you also have the chance to splurge on a two-night pre-cruise package near Elvis' former home Graceland .

Ports of call include Paducah, Kentucky; Dover, Tennessee; and Clarksville, Tennessee, with an overnight in Nashville and an included excursion to a show at the Grand Ole Opry. Two scenic sailing days feature picturesque views of America's Heartland along the Mississippi, Ohio and Cumberland rivers as well as Lake Barkley.

2024 dates: In 2024, there are two available itineraries in September and November.

Grand Heartland Cruise: St. Paul to New Orleans

Length: 15 days Price: Starts at $9,455 per person

This 15-day voyage allows you to explore America's rich history in towns along the Upper and Lower Mississippi River. The immersive voyage covers six states and 12 cities including St. Paul, Minnesota ; Dubuque, Iowa; St. Louis, Missouri ; Memphis, Tennessee; Natchez, Mississippi; Baton Rouge, Louisiana ; and more.

Take a step back in time while visiting Mark Twain's boyhood home in Hannibal, exploring stately historic estates in Natchez and Civil War sites in Vicksburg. At the end of a busy day ashore, you'll have plenty to chat about with fellow passengers during the evening cocktail hour.

2024 dates: American Heritage – ACL's traditional paddle-wheeler – and three modern riverboats set off on this journey from August to October in 2024.

Complete Mississippi River Cruise: New Orleans to St. Paul

Length: 22 days Price: Starts at $14,935 per person

If you want to see the entire Mississippi in one shot, check out this multiweek sailing that begins in New Orleans and ends in St. Paul, Minnesota. Along the way, you'll sail 1,393 miles, visit 10 states and experience a staggering 20 ports of call as you tour Louisiana and then head northbound to Minnesota.

In the South, walk the battlefields of the Civil War and sample delicious Southern barbecue before listening to the rhythms of jazz, the blues and rock 'n' roll. Then, explore the small and larger cities along the upper parts of the river. Remember to take time to gaze out at the picturesque scenery and the rolling farmlands of America's Midwest before disembarking in St. Paul.

2024 dates: Three of ACL's modern riverboats sail this itinerary in May, June and August in 2024.

The Great United States

Length: 60 days Price: Starts at $51,000

This two-month long journey – the longest domestic itinerary ever created – will check all the boxes for U.S. history and Civil War buffs, music and nature lovers, culinary enthusiasts, and beer and distilled spirits aficionados alike as the ship traverses America's iconic waterways through 20 states and 50 ports of call.

This epic journey showcases the natural beauty and living history of the U.S. from sea to shining sea. The sailing embarks in Portland, Oregon , on the Pacific Coast before traveling east to the Atlantic shore along four major rivers that highlight some of the country's most stunning coastlines. Upon arrival in New York Harbor, guests will have an unforgettable view of one of the most iconic landmarks in the U.S.: the Statue of Liberty .

Passengers can follow in the footsteps of Lewis and Clark along the Snake and Columbia rivers; cruise along Ol' Man River in search of Mark Twain and Elvis; see the vibrant colors of fall during peak season on the Hudson River; and take in the coastal breezes (and fresh seafood) along New England's rocky coastline.

This curated adventure also includes two flights: Jackson, Wyoming , to New Orleans as well as St. Paul to Portland, Maine , plus a land package through Glacier , Yellowstone and Grand Teton national parks. All-inclusive pricing covers the pre-cruise hotel stay, all flights and hotels between cruise segments, an ACL jacket and gear pack, daily excursions, all meals and beverages, gratuities and port charges, entertainment, and Wi-Fi.

2024 dates: The inaugural cruise sets sail on August 16, 2024.

Tips on Trips and Expert Picks

Travel tips, vacation ideas and more to make your next vacation stellar.

Viking River Cruises

Courtesy of Viking

Viking is no stranger to sailing Europe's rivers; the brand is synonymous with river cruising worldwide aboard its dozens of ships. However, Viking River Cruises is a newcomer to U.S. rivers, with its purpose-built ship: the 386-passenger Viking Mississippi. Looking to carve out its own niche in the American river cruising category, Viking claims it has the region's "first truly modern cruise ship" with its distinct Scandinavian design and expansive top sun deck with an infinity plunge pool.

Viking's mostly all-inclusive fares include a complimentary excursion in each port, destination lectures and performances, beer and wine at meals, free Wi-Fi, specialty coffees and teas, and more. The line offers five itineraries ranging in length from eight to 22 days along the Mighty Mississippi. Pre- and post-cruise extensions can be added to all voyages for an additional expense.

New Orleans & Southern Charms: Round-trip from New Orleans

Length: Eight days Price: Starts at $3,999 per person

If you don't know which Viking Mississippi itinerary to choose, start here. A round-trip voyage from New Orleans is convenient for booking flights and offers an excellent opportunity to extend your stay in NOLA. Six guided tours are included across eight days, from the historic estates of Natchez to Vicksburg National Military Park. A stop in St. Francisville gives you the chance to marvel at some of the 140-plus buildings it has on the National Register of Historic Places.

If you extend your stay in New Orleans, plan to sample the local Creole cuisine and take in some of the city's nightly jazz entertainment. In the morning, grab a beignet and a steaming cup of chicory coffee au lait at the original Café du Monde in the French Market.

2024 dates: This itinerary is available on select dates in February, November and December.

Heart of the Delta: New Orleans to Memphis

Length: Nine days Price: Starts at $4,299 per person

Similar to its round-trip New Orleans Southern Charms itinerary, the Heart of the Delta cruise begins in New Orleans and calls on the same five ports, before sailing through the Lower Mississippi and disembarking in Memphis. Enjoy scenic views of the serpentine river route – perhaps with expert commentary or a local cooking demonstration – and then take time to explore the birthplace of the Memphis blues, which is also a center of civil rights history.

2024 dates: In 2024, this cruise is available in February, March, April, May, June and November.

America's Great River: St. Paul to New Orleans

Length: 15 days Price: Starts at $12,999 per person

This Viking voyage sails from St. Paul to New Orleans on a two-week trip that calls on 13 ports with one day of scenic sailing. This itinerary combines the best of Viking's other Mississippi sailings for an all-encompassing Midwestern and Southern experience with 12 guided tours.

Included in the fare is a tour of Graceland; a stroll through small-town Burlington, Iowa, to see Snake Alley, deemed the most crooked street in the world; and a visit to the National Eagle Center of Red Wing, among others. For an additional fee, hop on an airboat ride through the Atchafalaya Swamp in Baton Rouge or tour the Anheuser-Busch Brewery of St. Louis.

2024 dates: Viking has availability for this itinerary in July, September and October.

Want to cruise the Mississippi River? See the top cruises on GoToSea , a service of U.S. News.

You may have seen riverboat gambling ships or are at least familiar with riverboat gambling along U.S. waterways. However, while high rolling on the river sounds like an exciting way to spend a night (or two, or more) while on your riverboat cruise, you'll have to jump ship to play the slots, roll the dice, spin the wheel or play a hand of Texas Hold 'em. Gambling on cruise ships sailing on internal waters is prohibited by U.S. law.

Gambling on boats in the U.S. is a complicated matter. While you will find some ships sailing along American waterways that are only set up for gambling, they are not carrying passengers from port to port. Most vessels that feature riverboat gambling are now moored, offering sports betting, table games, entertainment, live music and dancing while tethered to shore.

Why Trust U.S. News Travel

Gwen Pratesi has been an avid cruiser since her early 20s. She has sailed on nearly every type of cruise ship built, including the newest megaships, paddle-wheelers on America's waterways, and an 18-stateroom river ship on the Mekong River in Vietnam and Cambodia. Most recently, she traveled on a small luxury expedition vessel in Antarctica and crossed the notorious Drake Passage twice. She covers the travel and culinary industries, specializing in cruises, for major publications including U.S. News & World Report.

You might also be interested in:

• The Top River Cruise Lines
• The Top All-Inclusive Cruises
• Cruise Packing List Essentials
• The Top Cruise Insurance Plans

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Mississippi River Cruises

The Mississippi River is truly a force of nature and travels across multiple states in the USA such as Iowa or Illinois before flowing through the Gulf of Mexico. Being the fourth largest river in the USA means that a river cruise in Mississippi will reveal countless landmarks, breathtaking scenery and even wildlife. Discover premium river cruise companies and you've got yourself a dream holiday to relax and recharge.

34 Mississippi tour packages with 444 reviews

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• Coach / Bus

Music Cities: Nashville & Memphis

• Food & Culinary

Tastes and Sounds of the South (10 Days)

Well run and a lovely group of people

• €100 deposit on some dates Some departure dates offer you the chance to book this tour with a lower deposit.

Tennessee Music Trail to New Orleans

Rhythms of the Road (including Hammond)

tour took us exactly where we wanted to go with someone else doing the organising!

America's Musical Heritage

Excellent organization in all respects, Peter was overwhelming.

Rhythms of the South (11 Days)

Good trip! Great venue! Lots to do. Well looked after. Disappointed in Nashville quality inn. Staff not helpful and hotel very tired and could be cleaned better

Southern Sounds & Elvis

Great experience of seeing Tupelo/Memphis/Gracelands/Nashville with excellent company

• Christmas & New Year

Highlights of New Orleans

• Festival & Events

USA – New Orleans Mardi Gras Carnival

Bourbon, Beale & Broadway!

Got to be the best music tour ever! Brilliant holiday visiting the three most well known streets in America. Loads included, and loads to do and see - with plenty time to see everything. If you are looking for a value for money music cities tour - this is the one! Travelling Time - really look after you - and show you the meaning of great music holidays!

Country Roads of the Deep South (Classic, 12 Days)

Country Roads of the Deep South (Small Groups, 12 Days)

Boundary Waters

Southern Grace (Small Groups, 9 Days, Door To Door)

Simply Music Cities

Reviews of mississippi cruises.

A well planned and executed tour. Great way to see Nashville, Memphis, and New Orleans and learn the history of music during the day and listen to it at night.

Would’ve loved it to have been longer! An extra night in each main city would’ve been great for extra activities

The trip was wonderful. The itinerary was excellent and there was a good balance between structured tours and free time. Our tour guide and driver were professional, personable and helpful.

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• River Cruises

What to Know About Mississippi River Cruises — From the Cruise Lines to Top Itineraries

See small towns and bustling cities by boat on a Mississippi River cruise.

Elizabeth Rhodes is a special projects editor at Travel + Leisure , covering everything from luxury hotels to theme parks to must-pack travel products. Originally from South Carolina, Elizabeth moved to New York City from London, where she started her career as a travel blogger and writer.

River cruises are a great way to see the world — you can visit several waterfront destinations and watch the scenery pass by from cozy accommodations and top-deck lounges on intimate luxury ships. And while rivers like the Danube and the Rhine are top choices for many travelers, you don't have to go abroad for a memorable river cruise. You can access some of the nation's iconic attractions and favorite cities right from the Mississippi River.

There are three main cruise lines traveling the Mississippi, with journeys ranging from less than a week to more than 20 days. Spring and fall are the best times of year to take a cruise along the river, as you'll avoid the summer heat and winter chill and enjoy more pleasant weather while you take in the surroundings.

Here's what you need to know about Mississippi River boat cruises, from choice itineraries to popular stops.

Mississippi River Cruise Lines

There are three main cruise lines that offer itineraries along the Mississippi River: Viking River Cruises , American Queen Voyages , and American Cruise Lines . Viking is known for its luxury river, ocean, and expedition cruises to incredible destinations around the world, and trips aboard its 193-stateroom Viking Mississippi adhere to the same standard of service.

American Queen Voyages offers several itineraries along the Mississippi — one along the Upper Mississippi, another on the Lower Mississippi, and one that also sails a portion of the Ohio River — on its signature paddle-wheel steamboats. The company's flagship, the American Queen, is said to be the world's biggest steamboat.

The itineraries on American Cruise Lines feature either modern riverboats or old-school paddle wheelers, so you can choose your ideal sailing experience.

All three cruise lines offer similar itineraries along the river, so we recommend looking into the ships, the amenities, and what's included in the rate (like pre-departure hotel stays and excursions) to help make your decision.

Popular Ports on the Mississippi

You can cruise all the way from New Orleans to Minneapolis, or you can sail shorter segments of the river. Typically, cruises along the Lower Mississippi sail between New Orleans and Memphis, while cruises on the Upper Mississippi sail between St. Louis and the Twin Cities.

Passengers on the Upper Mississippi may get the chance to hop off and explore Mark Twain's childhood home in Hannibal, Missouri, stroll the streets of Iowa's oldest city (Dubuque), or marvel at sacred bluffs in Red Wing, Minnesota. Along the Middle Mississippi, there's Paducah, Kentucky, a UNESCO-designated Creative City , and Chester, Illinois, the birthplace of Popeye the Sailor Man.

On the Lower Mississippi, you'll find Cajun culture in Baton Rouge, Louisiana, Civil War history in Vicksburg, Mississippi, and music and BBQ in Memphis .

Mississippi River Cruise Itineraries

There are many itineraries to choose from between the three major Mississippi River Cruise lines, but here are our top picks.

Viking River Cruises: America's Great River

Cruise from New Orleans all the way up to St. Paul on Viking's 15- or 17-day America's Great River itinerary aboard the 193-stateroom Viking Mississippi , a vessel designed just for this river. The journey starts in New Orleans and stops in Baton Rouge; Natchez and Vicksburg, Mississippi; Memphis; and St. Louis, where passengers can explore attractions like Gateway Arch National Park and the flagship Anheuser-Busch brewery. From there, it continues on to Hannibal, Missouri; Burlington, Davenport, and Dubuque, Iowa; La Crosse, Wisconsin; and Red Wing, Minnesota, where travelers can learn about America's most recognizable symbol at the National Eagle Center. In between action-packed stops, there's plenty of time to take in the scenery from your veranda or the boat's several public viewing areas.

American Queen Voyages: New Orleans to Memphis

Sail along the Lower Mississippi from New Orleans to Memphis on this nine-day cruise, which starts with a complimentary stay in New Orleans and a second day to enjoy the Big Easy. Then, it's on to Nottoway Resort and St. Francisville in Louisiana and Natchez, Vicksburg, and Greenville in Mississippi before a day of cruising through the Delta and disembarking in Memphis. There are a few different paddle-wheel riverboats that cruise this route for American Queen Voyages — find the specific ship for your journey when you select a date.

American Cruise Lines: Upper Mississippi River Cruise

This eight-day cruise starts in St. Louis and sails along the Upper Mississippi to St. Paul. Stops along the way include Hannibal, Missouri; Fort Madison, Davenport, and Dubuque, Iowa; and Winona and Red Wing, Minnesota. Several riverboats cruise this route, including American Melody and American Symphony , inaugurated in 2021 and 2022, respectively. These sister vessels offer large rooms and suites with contemporary furnishings and an upscale feel.

Phone 800 331-1467

It’s Twilight Time

2-Day Cruise

Our signature cruise.

1-Day Cruise

North into the valleys.

Sightseeing Cruise

1 1/2 hour • leclaire.

2024 Cruise Schedule

The riverboat twilight.

Since 1985, the Riverboat Twilight has delivered one of the most exceptional cruise experiences in the Midwest. And it’s not just a cruise; it’s a conduit to reconnection, relaxation, and renewal.

Marvel at the majestic Mississippi river while relaxing in style aboard a stunningly replicated Victorian Riverboat. Allow yourself to be pampered by the Twilight’s attentive, informative, and welcoming crew. Delicious meals are prepared on board in the lower galley, while a full bar complete with top shelf liquors provides custom drinks to enhance your experience.

The Riverboat Twilight is family-owned and operated business, with a focus providing entertaining and quality cruises. The 140-passenger vessel has ample indoor, and outdoor seating on all three decks, and wrap-around windows give way to amazing views.

Our 2024 season offers 1-day, 2-day, and sightseeing cruises departing from LeClaire & Dubuque, Iowa.

Where the river runs deep, so do the discoveries.

Absolutely perfect in all ways!

My Friend and I went on the Riverboat Twilight and it was the most perfect/awesome adventure! From reserving our trip to our final walk to our car after the two day cruise, all was perfect! Staff are amazing, from the Captain to the servers, to the musical entertainers. The food is suburb and generous! Everything is very well organized, from our luggage/hotel in Dubuque/seating for meals, free shuttles in Dubuque, etc! The scenery and info along the way from the captain was wonderful! This was an absolutely perfect two day cruise, and we are going again in Mid October as we loved it so much!!.

The service by all involved was first class all the way!

We were very impressed by the personal service we received by the staff and everyone involved. The trip was very nice from a sightseeing perspective, interesting from a historical perspective and very relaxing overall. Plus the food was plentiful and excellent. We highly recommend this cruise to everyone!

Wonderful relaxing two days....

Extremely enjoyable trip. The cruise itself was delightful as you slowly moved up and down the river enjoying the wildlife and listening to the Captain explain the view and history. Unless you are a very big eater you have to be selective as they feed you FIVE times a day. Not only is the food plentiful but it is also very good. The Grand Resort in Dubuque was a nice stay as we had a view of the river. There was adequate time to explore some of the sights In Dubuque. I think we will do this trip again in the future…….

3 F's; Food, Food, and Fun

Excellent team from the captain to the crew provide a relaxing time..The chefs do an excellent job and there is more great food than you can imagine. This is the most organized and professional staff that we have ever experienced. No detail is overlooked.

Riverboat Twilight 360° Tours

Pilot house.

Deck 3 Stern

Downtown LeClaire Near Dock

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If you are not vaccinated, we strongly encourage you to do so, however, at this time the Riverboat Twilight does not ask for proof of vaccination. Mask wearing is the choice of the individual. The Twilight offers ample indoor and outdoor seating on all three decks and plenty of fresh air.

We will continue to maintain our increased sanitization efforts of the TWILIGHT and our boarding facilities, and we continue to provide hand sanitizer aboard the boat and employ a strong air purifier that uses UVC lighting that has been proven to destroy viruses and other bacteria.

For the safety of our passengers and crew and to maintain proper cleanliness, we have implemented the following guidelines for parents of children under the age of 14. While onboard the vessel and when making use of our food and beverages services, children must be accompanied by an adult at all times. With your cooperation and understanding, we will be able to continue to offer a safe and enjoyable experience for everyone.

As an owner, of the Holiday Inn Express & Suites Le Claire, IA and the President of Great Lakes Management Group which manages the hotel’s day to day operations, I wanted to say thank you. The business relationship with the Riverboat Twilight and her passengers is valued and much appreciated. We all know businesses from every industry has been operating in a different environment the last 8 weeks and will encounter new changes in the future.

We continue to monitor the franchise, local, state and federal safety guidelines to insure our guest and staff safety. For example, we anticipate a few changes in the near future which will include the following: a plastic shield / barrier at the front desk check,  revised breakfast offerings without a buffet setting, hand sanitizer located in the lobby and all floors at the elevator landings, continued use of hospital grade products to clean and sanitize the guest rooms, individual sanitizer wipes as an in-room amenity, removal of all products in the rooms that are reusable for example, pens, pads, laundry bags, and throw pillows, these items will be available upon request. We hope to see you soon. Stay safe and healthy!

  Respectfully, Neil Densmore | President glmg | hotels

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The Best Mississippi River Cruises to Discover America's Heartland

By Jackie Sheckler Finch

The luxury ships and historic tours are nice, yes. But the real star of Mississippi River cruises has always been the river. There’s nothing quite so Americana as getting to know the many personalities of this 2,350-mile stretch, flowing from northern Minnesota’s Lake Itasca through 10 states until it reaches Louisiana , where the Mississippi River Delta gives way to the Gulf of Mexico.

The slow, meandering journeys of Mississippi River cruises have long proven an ideal way to discover the distinct stories of America’s heartland. In the words of Mark Twain (which no Mississippi River story would be complete without), the towns and cities located on the mighty river's shores are “cheering to the spirit” and “reposeful as a dreamland,” with “nothing to hang a fret or a worry upon.”

The challenge modern travelers now face is when, where, and how to go about this iconic American voyage . Below, see our answers to these frequently asked questions, plus our favorite Mississippi River cruises to book in 2024.

Which cruise lines do Mississippi River cruises?

After American Queen Voyages shut down in February, only two Mississippi River cruise lines currently remain in operation.

Celebrating its 50th anniversary, American Cruise Lines (ACL) has a fleet of more than 20 American-built ships sailing across the country and remains family-owned and American-crewed. ACL offers a Mississippi River fleet of three luxurious 180-passenger modern riverboats– American Melody , American Symphony , and American Serenade —plus two classic paddlewheel ships, the 180-passenger American Splendor and the 150-passenger American Heritage.

The new kid on the Mississippi is the Viking Mississippi, a 386-passenger, five-deck vessel that first set sail in September 2022. The cutting-edge cruise is Viking’s first foray in the US, adding to their fleet of more than 90 ocean, river, and expedition vessels navigating the world’s seven continents.

What is the average cost of a Mississippi River cruise?

For an 8- or 9-day cruise, the average cost of a Mississippi River cruise is around $4,000 per person in a stateroom. Although prices might seem high initially, many of these cruises include extras that aren’t always complimentary on ocean cruises such as free WiFi, at least one free shore excursion in every port, paid port taxes and fees, and a pre-cruise hotel stay. Viking offers complimentary beer, wine, and soft drinks with onboard lunch and dinner. Meanwhile, American Cruise Lines offers complimentary beer, wine, cocktails, and soft drinks. Gratuities are also included in American Cruise Lines fares.

What is the best time of year to go on a river cruise?

Spring (late March through mid-June) and autumn (September through November) are the best times of year to go on a river cruise in the US. Spring blossoms add a colorful touch to the shoreline, and you can never go wrong with autumn foliage. The temperatures are mild, if not pleasantly cool, and passengers are eager to welcome a new spring travel season—or to enjoy one last autumn river adventure before winter arrives.

What month is best for a Mississippi River cruise?

If we had to pick just one, September is the best month for a Mississippi River cruise. The weather is usually mild with less likelihood of rain, and autumn colors are beginning to paint the shoreline. Keep in mind, however, that the Mississippi is the fourth largest river in the world—so temperatures any time of year are not going to be the same in warmer Louisiana as they are in cooler Minnesota.

Below, see our favorite Mississippi River cruises to book in 2024, featuring stops in iconic American cities like Nashville , Memphis , and New Orleans .

22-day Mississippi River Odyssey: New Orleans to Red Wing, Minnesota

Enjoy the charms of America’s great river on a journey aboard the Viking Mississippi from New Orleans to Red Wing, departing September 20. Custom built to sail American waters, the vessel features river-facing staterooms with either French or step-out balconies.

Stops include Baton Rouge and St. Francisville in Louisiana; Natchez, Vicksburg, Greenville, and Rosedale in Mississippi; Memphis in Tennessee; Paducah in Kentucky; Cape Girardeau, St. Louis, and Hannibal in Missouri; Burlington, Quad Cities, and Dubuque in Iowa; La Crosse in Wisconsin; and ending in Red Wing, Minnesota.

With so many fascinating shore excursions to choose from, it’s well worth taking time to tour the St. Louis Arch . Opened in 1965, the monument to America’s westward expansion is far more than just a stunning photo by the riverside. Venture underground between the arch legs for a museum. Climb aboard a tram to be transported 630 feet up to the top of America’s tallest monument for some stunning views.

12-day Heart of the Delta: Memphis to New Orleans

The 386-guest Viking Mississippi spans five decks, making it one of the largest passenger vessels on the Mississippi. Inaugurated in 2022, the ship features a modern Scandinavian design with an infinity pool and a two-story Explorers’ Lounge observation area similar to its ocean ships. Directly in front of the Explorer’s Lounge is an expanded outdoor seating area known as The Bow. Three restaurants serve both Southern regional cuisine and international favorites.

The cruise starts in Memphis on November 14 and includes stops in Rosedale, Greenville, Vicksburg, and Natchez in Mississippi as well as St. Francisville, Baton Rouge, and Darrow in Louisiana, ending in New Orleans. The “Mississippi Sings the Blues” shore excursion visits iconic sites along the Mississippi Blues Trail such as historic Dockery Farms, considered the “birthplace of the blues.”

The tour stops in Clarksdale, the fabled “Crossroads” where legend says blues great Robert Johnson reputedly sold his soul to the devil in exchange for his guitar prowess. Stops at the GRAMMY Museum Mississippi and the Delta Blues Museum completes this perfect trip for music lovers.

9-day Music Cities Cruise: Nashville to Memphis

Music is the main focus of this cruise offered by American Cruise Lines, which begins in Nashville on July 9 with an unforgettable visit to the legendary Grand Ole Opry and ends in Memphis, where passengers will enjoy live music on Beale Street and a tour of Elvis Presley’s Graceland . On board the American Splendor, passengers will enjoy spacious cabins and popular rocking chairs. First inaugurated in 2016 and fully redecorated in 2022, this ship offers the nostalgia of a classic paddlewheeler along with the comfort of modern amenities.

While in Nashville, explore the Johnny Cash Museum, then walk upstairs to The Patsy Cline Museum. Nightly entertainment spotlights the musical heritage of this region as the world’s newest paddlewheeler journeys along the river. The itinerary also includes Clarksville and Dover in Tennessee plus Paducah in Kentucky. In Paducah, stroll along the riverfront with more than 50 life-sized panoramic murals depicting Paducah’s past. Stop by Paducah’s National Quilt Museum, the world’s largest museum devoted to quilt and fiber art.

23-day Complete Mississippi River Cruise: New Orleans to St. Paul

Sail 1,393 miles through 10 states on a comprehensive exploration of the mighty Mississippi on the new American Serenade . Inaugurated in 2023, the 91-cabin American Serenade won Best New River Cruise Ship of the Year 2023 by Cruise Critic , the first time an American ship has received this prestigious award.

“With extra-large all-balcony staterooms and suites, trendy interior décor, an innovative hydraulic bow and retractable ramp, and one of the most gorgeous sun decks we’ve seen on a river-going ship, American Serenade sets the bar for domestic US river cruising high,” the award notes.

The epic itinerary beginning July 18, 2024 includes 22 ports of call including Oak Alley, Houmas House, Baton Rouge, and St. Francisville in Louisiana; Natchez, Vicksburg, Greenville, and Tunica in Mississippi; Memphis in Tennessee; Cape Girardeau, St. Louis, and Hannibal in Missouri; Muscatine and Dubuque in Iowa; and Winona, Red Wing, and Saint Paul in Minnesota.

Jessica Puckett

Hannah Towey

Karthika Gupta

12-day Mississippi River Gateway Cruise: New Orleans to St. Louis

From the French Quarter in New Orleans to the towering Gateway Arch in St. Louis , this American Heritage cruise lives up to its name. Inaugurated in 2015 and totally redecorated in 2022, the 84-cabin American Heritage is the perfect vessel for this interesting itinerary, its design reminiscent of the days when steamboat paddlewheelers plied the Mississippi in the 1800s.

The 12-day voyage departs from New Orleans on July 2. Ports of call along the way include Baton Rouge in Louisiana; Natchez and Vicksburg in Mississippi; Memphis in Tennessee; and Paducah in Kentucky . An onboard expert shares tales of the importance of steam-driven paddlewheels in establishing riverfront communities along the great Mississippi River.

Step ashore in Natchez and enjoy a cold drink at the Under-the-Hill-Saloon, once one of the rowdiest establishments on the Mississippi River in the 1800s. Legend says that Mark Twain stopped here when he was just another riverman named Samuel Clemens.

9-day Lower Mississippi River Cruise: Memphis to New Orleans

This nine-day American Melody cruise departs Memphis on September 8 and features eight ports of call including Vicksburg and Natchez in Mississippi, and St. Francisville, Baton Rouge, and Houmas House in Louisiana. At Vicksburg Military Park, learn how the 101st Airborne Division got its “Screaming Eagles” nickname, plus the tale of its famous soldier, a young guitar player named Jimi Hendrix. At Houmas House, see the bedroom where Bette Davis stayed to film the 1964 movie Hush, Hush, Sweet Charlotte . Joan Crawford was the intended co-star but Bette and Joan feuded so Joan quit and Olivia de Havilland replaced her.

Launched in 2021, the five-deck American Melody has 91 staterooms, all with private balconies and full-length sliding glass doors. The ship has several spacious lounges, a fitness center, large dining room, café for casual dining, sun deck, library, and an impressive four-story glass atrium in the center of the ship. The ship’s unusual bow opens and lowers a platform for passengers to easily walk ashore.

9-day Upper Mississippi River Cruise: St. Louis to St. Paul

Board the American Symphony cruise ship to visit Mark Twain’s hometown and experience the real-life inspiration behind Life on the Mississippi, the classic memoir chronicling the author's days on the river as a steamboat pilot.

The 91-cabin American Symphony, recently inaugurated in 2022, has 100% private balcony accommodations and a unique bow that opens with a retractable gangway that can be extended for landings virtually anywhere. The ship also features lounges soaring 40 feet above the water with triple the glass of other riverboats for spectacular views. Comfy deck chairs welcome passengers to enjoy the undeveloped countryside, picturesque islands, and fascinating dams and navigation locks.

Departing September 27, this itinerary features seven ports of call including Muscatine and Dubuque in Iowa, and Winona and Red Wing in Minnesota. In Hannibal, visit the actual home—with a whitewashed Tom Sawyer fence—where Samuel Clemens (Mark Twain) grew up. In Dubuque, see the 1989 “Field of Dreams” movie site known for the famous quote, “If you build it, they will come.”

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Mississippi River Cruises

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Family-Friendly Tours Full Of Adventure, Storytelling, And Fun

History, literature, and travel enthusiasts unite for a unique sightseeing and dining experience aboard riverboat cruises on the Mississippi River from beloved author Samuel Clemens, aka Mark Twain's hometown of Hannibal, Missouri. Witness firsthand what inspired the writer to create iconic characters, Tom Sawyer and Huck Finn. At Mark Twain Riverboat Co., you get to experience the Mighty Mississippi River in a truly memorable way, a Mississippi river boat cruise complete with storytelling, scenic views, and fine dining.

We provide a unique experience perfect for individuals, families, and groups. The cruise takes place on the Mississippi River from Mark Twain's boyhood home town of Hannibal, MO.

Mark Twain shared his unique perspective of life on the Mississippi River throughout his writings and characters. Get a glimpse of the Mississippi River as Mark Twain might have seen it.

The Mark Twain has been a unique feature on the Hannibal riverfront for more than 30 years. As a family-owned business since 1997, we strive to offer you a unique riverboat experience on the Mighty Mississippi, whether you’re a Hannibal resident or visitor. Choose between our two daily cruise offerings: our Sightseeing Cruise and our evening Dinner Cruise which includes live entertainment and a two entree buffet-style dinner.

Whether you are looking for a sightseeing adventure on the Mississippi River, taking in the sights, or dining on the river at sunset, Mark Twain Riverboat has something for everyone.

Set Sail on Our Riverboat Cruises

Sightseeing Tour

This one-hour sightseeing cruise travels along the mighty Mississippi River, allowing you to soak up the scenery at a relaxing, rhythmic pace. Listen as the captain guides your cruise with historical commentary on the history, legends, and sights of the Mississippi River.

A cruise aboard the Mark Twain Riverboat is great for family events. Whether you are a visitor or resident of Hannibal, you can make wonderful memories aboard our unique riverboat experience! Looking forward to having you onboard!

Departure time: Varies - check calendar Yearly availability: April 1 - Nov. 4 Weekly availability: Daily

Dinner Cruise

Enjoy a night of dinner and dancing on this cruise on the Mighty Mississippi. Indulge in a delicious buffet and share a wonderful dinner with your family or friends, then enjoy live music from the dance floor or the deck.

Once on board, you are escorted to your table, then you are free to roam the boat until the captain announces that dinner is ready. After dinner, you are free to dance or sit back and enjoy the music. Live entertainment is included on our Dinner Cruises. It may be The Rivermen playing modern jazz (Saturday night from Memorial Day thru September), or you might get to enjoy the music of Tim Hart (Mondays & Tuesdays), or Adam Ledbetter and David Damm (Sunday, Wednesday, Thursday and Friday). Listen or dance to their favorite tunes — and they have been known to take a request or two. And you never know when a crew member or two may step up on the stage and join in.

Departure time: 6:30 p.m. Yearly availability: May 3 - Oct 28 Weekly availability: Varies - check calendar

Why choose us?

A Glimpse At Missouri Through The Lens Of A Famous Author On The Mississippi River

A Mississippi River cruise aboard Mark Twain Riverboat Co. allows you to enjoy a short excursion from Hannibal during the more pleasant weather months of the year. Just 100 miles away from St. Louis, our Mississippi River boat cruise is the only cruise that departs from Mark Twain's boyhood home.

River cruising gives you the time and space to fully immerse yourself in Mark Twain's story and the Mississippi River, getting to know the inspiration behind his books. We handle every detail for you from departure to dinner on our Mississippi river cruises, making it possible for you to fully relax and enjoy our modern riverboat.

Cruising down the river is a great way to unwind and enjoy nature after a busy week. Hannibal, Missouri is home to some of the most scenic riverfront views in the Midwest!

Informative

Our cruise guides are experts in their field and love to share their knowledge about this beautiful city. They'll educate you all about the history of the area and its inhabitants, so you can really get an insider's look at this fascinating area.

Family-friendly

Our cruises are great for families with children of all ages, so bring your whole crew along with you! We have plenty of activities that will keep you occupied during the day and night.

Hannibal, Missouri

Despite its small size, Hannibal, MO is full of history and immersive learning experiences. It is there that you can visit Mark Twain's boyhood home and museum, take a Mississippi River cruise, or even attend a festival in his honor. That's not all there is to do in the area, though. You can explore caves and even take a ghost tour. Although, we are sure our cruise will be one of your favorite experiences yet.

Upper Mississippi River cruises are a great way for people of all ages to take a break from the normal day-to-day. Instead you'll enjoy an afternoon taking in the beautiful scenery or an evening of entertainment and dining. Our cruises are perfect for anyone who wants adventure but doesn't want the length of trip that most American cruise lines offer. A short trip aboard our Mississippi River cruises is just the evening out you need to feel refreshed, educated, and creative.

Frequently asked questions

Can we modify existing itineraries.

To some extent – yes. Sometimes we will have to because the weather isn’t always ideal and we want to stay in shallow, calm waters to keep the trip enjoyable.

What is the duration of the cruises?

Our cruises last approximately one to two hours

Are food and drinks available on board?

Yes, we offer a variety of food and drinks, including a snack bar and a full-service bar.

Is smoking allowed on board?

No, smoking is not allowed onboard.

Is the Mark Twain Riverboat wheelchair accessible?

We are wheelchair accessible on the lower deck. However, there is no lift to the upper deck and wheelchairs do not fit in the bathrooms.

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Mississippi River Cruises

Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, our new cruises on the "Mighty Mississippi" offer a different type of cross-country journey for the curious explorer—one that allows you to be immersed in American history and culture.

Step on board the newest and most modern ship on the Mississippi with all outside staterooms, private verandas, spacious public areas and our signature, clean Scandinavian design, reimagined for the Mississippi River.

NEW! Mississippi Delta Explorer

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Highlights of mississippi river cruises.

A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port. Here are a few highlights Viking reveals to you:

• Festive French Quarter and Creole cuisine in New Orleans
• Cajun heritage in Baton Rouge
• Civil War history at Vicksburg National Military Park
• Memphis BBQ, Graceland and appreciation of the Delta Blues
• Steamboat sailings with diverse wildlife sightings
• Mark Twain's boyhood home and America’s literary history
• Up close look at America’s national symbol, the bald eagle
• Gateway Arch in St. Louis and the pioneering spirit of the Midwest
• Norwegian cultural experience at Vesterheim
• Intricate locks and dams of the Upper Mississippi

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Lower Mississippi River Cruises

The Mississippi River is filled with diverse, culturally rich regions that promise historical, musical, and gustatory experiences unlike those found anywhere else in the world.

For this reason, our cruises are customized to suit the experience you are seeking — whatever that may be.

Are you a Civil War history buff? Do you treasure the writings of Mark Twain? Or do you seek a Mardi Gras full of dance, color, and delicious food? Prefer small towns and Southern hospitality?

No matter what aspect of this mighty river and its many facets appeals to you, we have the cruise of your dreams.

With ports of call that span the region — from St. Paul, Minnesota, (for our Upper Mississippi river cruises) to New Orleans, you’ll feel like the king and/or queen of the Mississippi.

Explore from St. Louis to St. Paul to St. Francisville — and points both north and south — with USA River Cruises on one of our quintessential American cruise line adventures!

Your Lower Mississippi Itinerary

You’ll enjoy between six and 22 days of fabulous food, music, camaraderie, and relaxation. Sit on the deck of one of our gorgeous paddle wheelers. This fantastic mode of travel slows life down and allows you to soak up every ounce of beauty along this iconic body of water.

Consider just a few of our fabulous Mississippi cruises: New Orleans to Memphis.

If you arrive in New Orleans a few days before the cruise launches, you have the opportunity to fully explore and experience the wealth of cultural amenities that abound in the Big Easy, including:

The Garden District : A fabulous and historic neighborhood, filled with oak-lined boulevards, grand mansions, and, of course, lush gardens. It’s also the location of the famed Lafayette Cemetery, which is the final resting place of several historical figures, including John Howard Ferguson, who was the defendant in the Supreme Court’s Plessy v. Ferguson decision that established the “separate but equal” doctrine that was later overturned in the 1950s.

French Quarter : No trip to New Orleans is complete without at least a walk-through of the famous district. Here you’ll find Bourbon Street — the beating heart of Mardis Gras — and Jackson Square, where ceremonies marking the transfer of the Louisiana Purchase territory from France to the United States took place in 1803.

Once you board our magnificent cruise ships, you’ll get to explore both the history and the modern amenities of the Big Muddy — as the Mississippi is sometimes called. You’ll cruise from New Orleans to Memphis, Tennessee (or the reverse!). It’s Mississippi Delta living at its finest.

Along the way, you’ll visit several more fabulous locations, including Baton Rouge, Louisiana, the state capital and home to Louisiana State University.

You’ll also experience wonderful Natchez, Mississippi, home to indigenous culture stretching back hundreds of years. You can even visit Longwood Plantation, which remains unfinished because workers abandoned it to fight in the Civil War. This is history at its most intimate and immediate.

One last point of interest (among many on your journey): Vicksburg, Mississippi, where you can tour the Vicksburg National Military Park and see for yourself artifacts of early American history, including gunboats and Civil War battlefields.

If you travel upriver, you’ll disembark at Memphis, but there’s a lot more to explore along the Mississippi, including St. Louis, Missouri, just a few hours upriver from Memphis. (Check out our other Mississippi cruises for more info.) If you travel downriver (Memphis to New Orleans), the sights and scenes are just as magical, and the sounds — from blues to bluegrass and rock ‘n’ roll — are as diverse as the scenery.

• American Serenade

We want to pause for a moment to make sure our guests know about an exciting addition to our Lower Mississippi river cruises: the American Serenade — ready to set sail in 2023!

It’s fitting that the overture to American Serenade’s cruise season will begin on the legendary Mississippi River. A with her sister ship, the American Symphony, the 175-passenger American Serenade features an updated modern interior design that integrates an elegant and refined aesthetic into our tradition for spacious comfort.

This ship’s interior design was inspired by the geography of the United States of America. The new interior design highlights natural textual elements and serene color palettes.

American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship.

And let’s not forget the accommodations. Ranging from a cozy 250 square feet to an expansive 650 square feet, all of its spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service.

The new ship also features an onboard fitness center and many spacious lounges where you can relax after the day’s adventures.

Ready to set sail on a Lower Mississippi River cruise?

USA River Cruises: Your Destination Awaits!

Our booking agents are ready to answer any questions you may have and to accommodate any and all special needs.

Each member of our staff is uniquely qualified to customize the trip of a lifetime. Most of us have taken these cruises ourselves and are intimately familiar with every detail of the journey, making us the best possible resource for you.

USA River Cruises specializes in rail trips and small-ship cruises. This means our ships typically hold fewer than 900 passengers — more often than not it’s much fewer than that!

We’re based in Vancouver, Washington, just across the mighty Columbia River from Portland, Oregon. Thus, our passion began locally, with ships on the Columbia. However, we have grown to appreciate river cruise vacations all over the United States — as well as all over the world!

Our agents are friendly and responsive; most have personal experience on board many of our ships. That’s why USA River Cruise agents are the small-ship cruising and cruise vacation experts.

Call us! We’re excited to help you launch your Mississippi River cruise.

Mississippi Delta Explorer

New Orleans, LA to Memphis, TN

• June 22, 2024, July 27, 2024, January 11, 2025 -- 26 more dates available.
• From $5,299
• Viking Mississippi
• New Itinerary for 2024 & 2025! Save up to $1000 off per Stateroom!

The Tennessee Rivers Cruise

Chattanooga, TN to Nashville, TN

• May 10, 2024, May 17, 2024, May 24, 2024 -- 9 more dates available.
• From $5,190

Music Cities Cruise-American Symphony

Memphis, TN to Nashville, TN

• August 2, 2024, August 9, 2024, August 16, 2024
• From $4,530
• American Symphony

Grand Heartland Cruise-American Serenade

St. Paul to New Orleans

• September 17, 2024, August 15, 2025
• From $11,090

Grand Heartland Cruise-American Melody

• August 2, 2024, October 17, 2025
• From $11,755
• American Melody

Lower Mississippi River Cruise-American Symphony

Memphis, TN to New Orleans, LA

• April 19, 2024, April 26, 2024, August 23, 2024 -- 10 more dates available.
• From $5,900

Great Smoky Mountains National Park – American Symphony

Knoxville, TN to Nashville, TN

• May 24, 2024, June 7, 2024, June 11, 2024 -- 1 more date available.
• From $7,690
• New Itinerary for 2024!!
• August 6, 2024, August 13, 2024, August 20, 2024 -- 3 more dates available.
• From $4,125
• American Splendor
• October 29, 2024

Music Cities Cruise-American Splendor

• June 18, 2024, June 25, 2024, July 2, 2024 -- 4 more dates available.

Music Cities Cruise-American Serenade

• October 15, 2024, November 5, 2024
• From $4,840

Lower Mississippi River Cruise-American Melody

New Orleans to Memphis

• April 19, 2024, April 26, 2024, May 3, 2024 -- 12 more dates available.
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7 best US river cruises

Whether you're fascinated by American history, culture and cuisine, or you've enjoyed river cruising in Europe but are now looking to explore closer to home, U.S. river cruises are an easy and enjoyable vacation option.

Choose from two main waterways for your U.S. river cruise: the Mississippi River — which flows through nine states from St. Paul, Minnesota, to New Orleans — or the Columbia and Snake rivers in Oregon and Washington. Some cruise lines also venture onto three smaller, lesser-known rivers: the Ohio, the Cumberland and the Tennessee. You can also explore New York's Hudson River on a fall foliage cruise.

For cruise news, reviews and tips, sign up for TPG's cruise newsletter .

Your choice of cruise line is equally limited. Just two companies offer multiple itineraries on U.S. rivers. American Cruise Line sails all the waterways mentioned above, while Viking offers itineraries solely on the Mississippi. Additionally, Lindblad Expeditions has introduced a food-and-wine-centric river cruise on the Columbia and Snake rivers.

Read on for our picks of the seven best U.S. river cruises. They range from seven to 15 nights and visit destinations in 16 states; itineraries take you through the colonial-heritage-rich Northeast, America's agricultural heartland and the pioneer routes of the Pacific Northwest.

American Cruise Lines' 8-night Music Cities Cruise

From Memphis blues and Elvis Presley's "Blue Suede Shoes" to Kentucky bluegrass and New Orleans jazz, American Cruise Lines' eight-night Music Cities Cruise sails you through a chronology of the U.S. music scene. You'll traverse three rivers (the Mississippi, Ohio and Cumberland) en route from Memphis to Nashville, or vice versa.

In Tennessee's two famous music cities, you'll have a chance to visit Elvis Presley's Graceland, stroll blues club-lined Beale Street and check out the Grand Ole Opry. You'll also visit Paducah, Kentucky, and Dover and Clarksville in Tennessee, where experiences include whiskey and bourbon tasting, tours of landmark art murals and, of course, Civil War history.

While cruising, you'll enjoy nightly entertainment that celebrates the region's musical heritage. American Cruise Lines offers this itinerary on four ships from April to October 2024, 2025 and 2026. Three of the ships — American Melody, American Symphony and American Serenade — are 180-passenger modern river ships launched in 2021, 2022 and 2023, respectively. The fourth, American Splendor, is a 180-passenger paddlewheeler that debuted in 2016.

Related: Booking your first river cruise? Here's what you need to know

Viking's 14-night America's Great River Cruise

Want the total Mississippi experience? You can cruise the entire length of this mighty river as you visit 14 cities in seven U.S. states on Viking's two-week sailing.

Available three times a year (in July, September and October), the America's Great River cruise begins in Minnesota (either St. Paul or Red Wing) and concludes in New Orleans, allowing you to experience an intricate tapestry of American history and culture.

There's eagle spotting in Red Wing and agricultural innovation in Quad Cities, Iowa. You'll enjoy Mark Twain lore in Hannibal, Missouri, and architectural landmarks, such as the soaring Gateway Arch, in St. Louis. As you cruise the lower Mississippi, you'll delve into civil rights history in Memphis; Civil War battles and historic architecture in Mississippi's Vicksburg and Natchez; Cajun and Creole music in Baton Rouge; and the legendary culinary treats and jazz of New Orleans.

All sailings are aboard the 386-passenger Viking Mississippi. Launched in 2022, it's currently the largest river ship in the U.S. and features three restaurants and an aft infinity pool.

American Cruise Lines' 8-Night Columbia & Snake River Cruise

If your vacation preferences favor mountain landscapes, wine tasting and pioneer lore, consider American Cruise Lines' eight-night Columbia & Snake River Cruise . You'll explore the Pacific Northwest from Portland, Oregon, to Clarkstown, Washington (or vice versa).

On the Pacific end of your voyage, you'll visit Astoria, Oregon — the oldest American settlement west of the Rocky Mountains. This coastal city at the mouth of the Columbia River is known for its Victorian homes, wineries, brew pubs, and Lewis and Clark heritage. Next, from Kalama, Washington, you can join an excursion to visit the remnants of the area around Mount St. Helens, which suffered a devastating eruption in 1980.

In The Dalles, you can enjoy a sommelier-led tasting of Columbia Valley wines, visit Multnomah Falls or get adventurous on a river kayak tour. During a call on Richland, Washington, you can admire the scenic beauty around the confluence of the Columbia and Snake rivers at Sacajawea State Park. More wine tasting or outdoor adventure awaits on the way to Clarkstown.

American Cruise Line offers this itinerary on five ships from April to October 2024, 2025 and 2026. Three of the ships (American Song, American Jazz and American Harmony) are 180-passenger modern river ships launched from 2018 to 2020. American Pride is a 150-passenger paddlewheeler launched in 2012, and American West is a 110-passenger veteran paddlewheeler launched in 1995.

Related: Best river cruise lines around the world

Viking's 7-night New Orleans & Southern Charms

If you've never visited New Orleans, or it's been a while, take a Mississippi River cruise that sails round-trip from the Big Easy. They offer time before or after the cruise to enjoy the city's food, music and iconic architecture — plus the ease of a round-trip flight booking. Viking's seven-night New Orleans & Southern Charms itinerary focuses solely on ports in Louisiana and Mississippi, with an emphasis on historic architecture, Cajun culture and Civil War landmarks.

From Darrow, Louisiana, you'll stroll beneath canopies of towering live oak trees to visit historic mansions or glide through the bayou. More historic architecture, along with bird-watching, awaits in St. Francisville, Louisiana, and Natchez, Mississippi. Vicksburg, Mississippi, is home to one of the Civil War's most famous battlefields. Baton Rouge, Louisiana's capital, has something to satisfy every interest, from Cajun cuisine to tours of the restored World War II-era USS Kidd.

The cruise, which is available in November and December 2024 and January, November and December 2025, ends with a full day of exploration back in New Orleans before one last night aboard the 386-passenger Viking Mississippi.

American Cruise Lines' 7-night Hudson River Fall Foliage Cruise

Not only is the autumnal landscape in New York's Hudson Valley visually captivating, but the small cities and towns that line the river's shores are filled with fascinating early American history dating back more than 400 years.

Cruise the Hudson round-trip from New York City on American Cruise Lines' seven-night Hudson River Fall Foliage Cruise . You'll visit Catskill, home to the Hudson River School Art Trail and the Olana Historic Site, or explore more actively at the Hudson River Skywalk and Kaaterskill Falls. In Albany, founded in 1609, you can tour the newly renovated New York State Capitol building, built in the late 1800s; you can also visit the New York State Museum, which dates to 1836. Feel like apple-picking? That's an option here, too.

Next, during a call at Kingston/Hyde Park, you can tour the Franklin D. Roosevelt National Historic Site, home to the 32nd U.S. president's library and museum. You can also head to the Vanderbilt Mansion National Historic Site, featuring an American Beaux-Arts mansion completed in 1899. The United States Military Academy at West Point, founded in 1802, is also on the itinerary, as is Sleepy Hollow. The Sleepy Hollow legend comes to life during a tour of the local cemetery where author Washington Irving is buried. Back in the Big Apple on day seven, you'll have time to explore before saying farewell to your ship.

Sailings are available from late September to early November 2024, 2025 and 2026. Sailings are onboard either the 100-passenger American Eagle, American Liberty, American Glory or American Legend (all built in 2023 or 2024), or the older 90-passenger American Star and American Independence, launched in 2007 and 2010, respectively.

Related: River cruise packing list: What to pack when traveling by riverboat

Lindblad Expeditions' 7-night Columbia & Snake Rivers: Food, Wine and History Cruise

Nature-focused cruise line Lindblad Expeditions has partnered with Food & Wine magazine to offer a new seven-night Columbia & Snake Rivers: Food, Wine and History cruise on multiple dates in April, September and October 2024; there are also sailings in March, April, September and October 2025. The voyages will sail between Portland, Oregon, and Clarkston, Washington.

Complementing the itinerary will be gourmet Pacific Northwest cuisine and more than 40 regional wines curated by an onboard culinary team. All ingredients will be sourced from within 250 miles of the ship's route. A naturalist, historian and geologist will be on hand to guide you on excursions by foot, kayak, Zodiac and jet boat.

Off-ship experiences include sampling local beer and oysters in Astoria, Oregon; visiting Multnomah Falls or hiking Beacon Rock; and having a private vineyard visit and downtown wine walk in Walla Walla, Washington.

These sailings occur on two identical Lindblad ships: the 62-passenger National Geographic Sea Lion and National Geographic Sea Bird.

American Cruise Line's 15-night Grand Ohio River Cruise

Did you know that you can cruise from Pittsburgh to St. Louis? If exploring the central U.S. — Pennsylvania, Ohio, West Virginia, Kentucky, Indiana, Illinois and Missouri — without driving is appealing, consider the 15-night Grand Ohio River Cruise offered by American Cruise Lines. You'll enjoy regionally inspired dining and eclectic landmarks along the Ohio and Mississippi rivers as you sail.

Over two weeks, you'll visit Native American burial grounds and archeological sites in West Virginia and learn about the underground railroad in Ohio. You can taste bourbon and explore the Louisville Slugger Museum & Factory or the Kentucky Derby Museum & Horse Park in Louisville. Take time to appreciate American artistry at the National Quilt Museum in Paducah, Kentucky. Rest up from your portside adventures during five days of scenic river cruising.

This itinerary is available from June to August 2024, 2025 and 2026 on the 180-passenger modern river ship American Melody and the 150-passenger paddlewheeler American Heritage.

Planning a cruise? Start with these stories:

• The 5 most desirable cabin locations on any cruise ship
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• The ultimate guide to what to pack for a cruise
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• 21 tips and tricks that will make your cruise go smoothly
• Top ways cruisers waste money
• The ultimate guide to choosing a cruise ship cabin

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• New Orleans, Louisiana to St. Paul, Minnesota

NEW! Mississippi River Odyssey

• From $14,699
• 18 Guided Tours
• Dates & Pricing

NEW! Mississippi River Odyssey Map

Americana sights, sounds & flavors

Revel in the charm of “America’s Great River” as you set sail along the Mississippi. Admire the historic mansions and grand homes atop its bluffs, and delve into America’s Civil War history. Delight in the region’s famed Southern cuisine and sample Memphis’s renowned barbecue, alongside artisan beers. Birthplace of American music—blues, jazz and soul—the Mississippi celebrates its musical heritage in the towns and cities that line its legendary shores.

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Viking Inclusive Value

All you need included, with no surprises or hidden fees

To learn more about each port of call and our included as well as optional excursions, click on the individual days below.

Itinerary and shore excursions are subject to change and may vary by departure.

More features, services and excursions included

One complimentary shore excursion in every port of call

Free Wi-Fi (connection speed may vary)

Beer, wine & soft drinks with onboard lunch & dinner

24-hour specialty coffees, teas  & bottled water

Port taxes & fees

Ground transfers with Viking Air purchase

Visits to UNESCO Sites

Enrichment lectures & Destination Performances

Your Stateroom Includes:

River-view stateroom

Bottled water replenished daily

110/220 volt outlets

Queen-size Viking Explorer Bed (optional twin-bed configuration) with luxury linens & pillows

Private bathroom with shower, heated floor & anti-fog mirror

Premium Freyja® toiletries

Plush robes & slippers (upon request)

40" or 42" flat-screen Sony® TV with infotainment system featuring Movies On Demand, plus CNBC, CNN, FOX & more

Telephone, safe, refrigerator

Individual climate control

*All amenities on board Viking Longships; amenities vary on other ships.

Pre & Post Cruise Extensions

More days means more to discover, with extension packages you can add before or after your Viking cruise or cruisetour. Enjoy additional days to explore your embarkation or disembarkation city, or see a new destination altogether with a choice of exciting cities. Pre & Post Cruise Extensions vary by itinerary and are subject to change.

Pre: The Best of “The Big Easy”

From $949 | 2 Nights

Post: Cultural Capitals—Minneapolis & St. Paul

From $749 | 2 Nights

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The 7 Best Mississippi River Cruises for 2024

T he more than 2,300-mile Mississippi River invites travelers to discover its multifaceted heritage, with a vast range of deeply rooted culture, music and history. A cruise is a fantastic way to discover many of the riverfront cities on a single trip, from the comfort of your modern riverboat or traditional paddle-wheeler.

The following Mississippi River cruise itineraries can help you choose from cruises of various lengths and options for the Lower and Upper Mississippi. Note that all fares are listed as double occupancy (based on two people per cabin), and that they might not reflect taxes, port fees or gratuities. The itinerary availability listed is also subject to change.

American Cruise Lines

American Cruise Lines operates small ships accommodating between 90 and 180 passengers that are built, flagged and crewed in the U.S. – and it's the only company in the world operating a 100% U.S.-flagged fleet of riverboats and cruise ships. ACL's itineraries traverse waterways across 35 states, with 11 itineraries dedicated to the Mississippi River. Cruisers can choose to sail on modern riverboats with a sleek interior design or while away their time aboard classic paddle-wheelers reminiscent of days gone by.

ACL offers variety as well as versatility: This line boasts both the longest and shortest sailings on this list with cruises ranging from eight to 60 days in length, including The Great United States. This inaugural 60-day voyage spans four major rivers and 20 states, making it the longest U.S. river cruise in history.

Complimentary hotel and transportation packages are available from every departure city before your cruise. You can book certain premium packages for added perks, such as two nights spent next door to Graceland in Memphis – with VIP tickets and a city tour included in the price.

Music Cities Cruise

Length: Eight days

Price: Starts at $3,610 per person

Spend a week getting lost in the sounds of the Memphis blues, rock 'n' roll and country music legends on the seven-night Music Cities Cruise. A hotel stay the night before your sailing is included, but embarking in Memphis means you also have the chance to splurge on a two-night pre-cruise package near Elvis' former home Graceland .

Ports of call include Paducah, Kentucky; Dover, Tennessee; and Clarksville, Tennessee, with an overnight in Nashville and an included excursion to a show at the Grand Ole Opry. Two scenic sailing days feature picturesque views of America's Heartland along the Mississippi, Ohio and Cumberland rivers as well as Lake Barkley.

2024 dates: In 2024, there are two available itineraries in September and November.

Grand Heartland Cruise: St. Paul to New Orleans

Length: 15 days

Price: Starts at $9,455 per person

This 15-day voyage allows you to explore America's rich history in towns along the Upper and Lower Mississippi River. The immersive voyage covers six states and 12 cities including St. Paul, Minnesota ; Dubuque, Iowa; St. Louis, Missouri ; Memphis, Tennessee; Natchez, Mississippi; Baton Rouge, Louisiana ; and more.

Take a step back in time while visiting Mark Twain's boyhood home in Hannibal, exploring stately historic estates in Natchez and Civil War sites in Vicksburg. At the end of a busy day ashore, you'll have plenty to chat about with fellow passengers during the evening cocktail hour.

2024 dates: American Heritage – ACL's traditional paddle-wheeler – and three modern riverboats set off on this journey from August to October in 2024.

Complete Mississippi River Cruise: New Orleans to St. Paul

Length: 22 days

Price: Starts at $14,935 per person

If you want to see the entire Mississippi in one shot, check out this multiweek sailing that begins in New Orleans and ends in St. Paul, Minnesota. Along the way, you'll sail 1,393 miles, visit 10 states and experience a staggering 20 ports of call as you tour Louisiana and then head northbound to Minnesota.

In the South, walk the battlefields of the Civil War and sample delicious Southern barbecue before listening to the rhythms of jazz, the blues and rock 'n' roll. Then, explore the small and larger cities along the upper parts of the river. Remember to take time to gaze out at the picturesque scenery and the rolling farmlands of America's Midwest before disembarking in St. Paul.

2024 dates: Three of ACL's modern riverboats sail this itinerary in May, June and August in 2024.

The Great United States

Length: 60 days

Price: Starts at $51,000

This two-month long journey – the longest domestic itinerary ever created – will check all the boxes for U.S. history and Civil War buffs, music and nature lovers, culinary enthusiasts, and beer and distilled spirits aficionados alike as the ship traverses America's iconic waterways through 20 states and 50 ports of call.

This epic journey showcases the natural beauty and living history of the U.S. from sea to shining sea. The sailing embarks in Portland, Oregon , on the Pacific Coast before traveling east to the Atlantic shore along four major rivers that highlight some of the country's most stunning coastlines. Upon arrival in New York Harbor, guests will have an unforgettable view of one of the most iconic landmarks in the U.S.: the Statue of Liberty .

Passengers can follow in the footsteps of Lewis and Clark along the Snake and Columbia rivers; cruise along Ol' Man River in search of Mark Twain and Elvis; see the vibrant colors of fall during peak season on the Hudson River; and take in the coastal breezes (and fresh seafood) along New England's rocky coastline.

This curated adventure also includes two flights: Jackson, Wyoming , to New Orleans as well as St. Paul to Portland, Maine , plus a land package through Glacier , Yellowstone and Grand Teton national parks. All-inclusive pricing covers the pre-cruise hotel stay, all flights and hotels between cruise segments, an ACL jacket and gear pack, daily excursions, all meals and beverages, gratuities and port charges, entertainment, and Wi-Fi.

2024 dates: The inaugural cruise sets sail on August 16, 2024.

Raw HTML : Tips on Trips and Expert Picks

Viking River Cruises

Viking is no stranger to sailing Europe's rivers; the brand is synonymous with river cruising worldwide aboard its dozens of ships. However, Viking River Cruises is a newcomer to U.S. rivers, with its purpose-built ship: the 386-passenger Viking Mississippi. Looking to carve out its own niche in the American river cruising category, Viking claims it has the region's "first truly modern cruise ship" with its distinct Scandinavian design and expansive top sun deck with an infinity plunge pool.

Viking's mostly all-inclusive fares include a complimentary excursion in each port, destination lectures and performances, beer and wine at meals, free Wi-Fi, specialty coffees and teas, and more. The line offers five itineraries ranging in length from eight to 22 days along the Mighty Mississippi. Pre- and post-cruise extensions can be added to all voyages for an additional expense.

New Orleans & Southern Charms: Round-trip from New Orleans

Price: Starts at $3,999 per person

If you don't know which Viking Mississippi itinerary to choose, start here. A round-trip voyage from New Orleans is convenient for booking flights and offers an excellent opportunity to extend your stay in NOLA. Six guided tours are included across eight days, from the historic estates of Natchez to Vicksburg National Military Park. A stop in St. Francisville gives you the chance to marvel at some of the 140-plus buildings it has on the National Register of Historic Places.

If you extend your stay in New Orleans, plan to sample the local Creole cuisine and take in some of the city's nightly jazz entertainment. In the morning, grab a beignet and a steaming cup of chicory coffee au lait at the original Café du Monde in the French Market.

2024 dates: This itinerary is available on select dates in February, November and December.

Heart of the Delta: New Orleans to Memphis

Length: Nine days

Price: Starts at $4,299 per person

Similar to its round-trip New Orleans Southern Charms itinerary, the Heart of the Delta cruise begins in New Orleans and calls on the same five ports, before sailing through the Lower Mississippi and disembarking in Memphis. Enjoy scenic views of the serpentine river route – perhaps with expert commentary or a local cooking demonstration – and then take time to explore the birthplace of the Memphis blues, which is also a center of civil rights history.

2024 dates: In 2024, this cruise is available in February, March, April, May, June and November.

America's Great River: St. Paul to New Orleans

Price: Starts at $12,999 per person

This Viking voyage sails from St. Paul to New Orleans on a two-week trip that calls on 13 ports with one day of scenic sailing. This itinerary combines the best of Viking's other Mississippi sailings for an all-encompassing Midwestern and Southern experience with 12 guided tours.

Included in the fare is a tour of Graceland; a stroll through small-town Burlington, Iowa, to see Snake Alley, deemed the most crooked street in the world; and a visit to the National Eagle Center of Red Wing, among others. For an additional fee, hop on an airboat ride through the Atchafalaya Swamp in Baton Rouge or tour the Anheuser-Busch Brewery of St. Louis.

2024 dates: Viking has availability for this itinerary in July, September and October.

Want to cruise the Mississippi River? See the top cruises on GoToSea , a service of U.S. News.

FAQ Module : Travel - Top Mississippi River Cruises FAQs

Why Trust U.S. News Travel

Gwen Pratesi has been an avid cruiser since her early 20s. She has sailed on nearly every type of cruise ship built, including the newest megaships, paddle-wheelers on America's waterways, and an 18-stateroom river ship on the Mekong River in Vietnam and Cambodia. Most recently, she traveled on a small luxury expedition vessel in Antarctica and crossed the notorious Drake Passage twice. She covers the travel and culinary industries, specializing in cruises, for major publications including U.S. News & World Report.

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