blast and cruise anavar

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Anavar Cycle: How to Maximize Your Gains & FAQ

October 25, 2023

by: Inside Bodybuilding

Reviewed by: Dr. Thomas O'Connor MD, PA

Anavar (Oxandrolone) is arguably the most popular steroid in the world, with large numbers of men and women cycling it. Some people love Anavar so much that they blast and cruise it, meaning they run it all year round like TRT (testosterone replacement therapy).

Many steroids are taken solely by men; however, Anavar is the exception, hence its nickname, ‘the girl steroid’.

However, this isn’t to say Anavar is only for females, with many strongmen and powerlifters also utilizing this steroid due to its positive effects on strength.

Anavar’s benefits are well-known, with it having the ability to increase lean muscle mass while decreasing a person’s body fat percentage at the same time.

• 1.1 Anavar-Only Cycle (for Beginners)
• 2.1 Anavar and Test Beginner Cycle
• 2.2 Anavar & Test Intermediate Cycle
• 2.3 Anavar and Andriol (Oral Test) Cycle
• 3 3. Anavar and Winstrol Cycles
• 4 4. Anavar and Clenbuterol Cycle
• 5.1 Do you need to run a PCT?
• 5.2 Is a Liver Support Supplement Needed on Anavar?
• 5.3 “Can I Drink Alcohol With Anavar?”

Perhaps Anavar’s best trait is that it’s one of the   safest steroids you can take.

It does not produce harsh side effects, hence why women and children have taken this steroid with great success in research trials (for medicinal purposes).

This guide is designed to help you run an effective Anavar cycle to maximize results while reducing side effects (whether you’re a male or female, beginner, intermediate, or advanced steroid user).

Disclosure : We do not accept any form of advertising on Inside Bodybuilding. We monetize our practice via doctor consultations and carefully chosen pharmaceutical recommendations, which have given our patients excellent results.

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If you suffer from cachexia or osteoporosis and require Anavar for medicinal purposes, we recommend Prestige Pharmaceuticals due to their product efficacy and fast worldwide shipping (2–6 days).

Anavar is legal to purchase in some countries and not in others; thus, it is the responsibility of users to act within the confines of their native law.

Inside Bodybuilding does not condone the use of AAS via illegal means or for cosmetic use.

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1. Anavar-Only Cycle

Taking Anavar by itself is an effective cycle, often used by beginners and intermediates during a cutting phase. An Anavar-only cycle will enhance fat burning while adding some muscle mass when eating fewer calories.

In our experience, women will typically only run Anavar-only cycles, whereas men who have taken steroids before are more likely to stack them with other compounds.

An Anavar-only cycle is one of the best protocols for beginners  because it’s a mild steroid and thus won’t cause dangerous side effects in first-time users. Thus, it’s an optimal compound to use when introducing the body to steroids.

A few of our patients have admitted to being afraid of taking steroids (because of the toxic side effects), yet they feel comfortable running an Anavar cycle because of its mild nature.

Anavar-Only Cycle (for Beginners)

This is a typical Anavar-only cycle for beginners. This would be a mild and suitable cycle for a first-time steroid user. The follow-up cycle for this may begin with a dose of 20mg instead of 15mg and may be extended up to 8 weeks .

Typical results from an Anavar-only cycle

This Anavar cycle is suitable for women who are beginners . It’s very important to be cautious in regards to the dose and cycle length for women to avoid masculinization effects occurring.

We have found Anavar to be one of the best steroids for women , lowering the risk of virilization side effects (such as hair growth, clitoral enlargement, and smaller breasts). However, the above adverse effects, although uncommon, are still possible on Anavar (when incorrectly utilized).

By following this cautious cycle protocol, the risk of developing these side effects will be extremely low due to the small dose and short cycle length. We typically see virilization side effects gradually happen over a period of time; thus, a woman can simply discontinue her cycle if she begins to experience any unwanted symptoms.

Typical results from an Anavar-only cycle (female)

2. Anavar and Testosterone Cycles

Note : This cycle is only recommended for men due to testosterone causing virilization side effects in women.

If there’s a steroid besides Anavar that’s suitable for beginners to take, it would be testosterone .

Testosterone is the best steroid we have found in terms of risk vs. reward .

Testosterone will produce large increases in muscle mass and strength, with it being classified as a bulking steroid.

Our lipid profiles show that testosterone does not place significant strain on the heart, contrary to other steroids. Also, testosterone is not hepatotoxic (as it is an injectable). These are the two biggest concerns we have when someone is taking anabolic steroids (protecting the heart and liver).

In regards to side effects, testosterone suppression will be more significant when stacking Anavar with testosterone. Also, cholesterol levels will rise slightly higher compared to taking either one by itself. We have also found androgenic side effects such as oily skin, acne, and hair thinning (on the scalp) to be more prevalent with this duo.

The different types of injectable testosterone are:

• Test suspension
• Test cypionate
• Test enanthate
• Test acetate
• Test propionate
• Sustanon 250

These different types of testosterone are all the same steroid but with different esters, which can dictate how fast it’s absorbed and how long it stays in the body. The most popular forms of testosterone are enanthate and cypionate, due to their price and ease of injection.

Anavar and Test Beginner Cycle

This cycle may be taken after an Anavar-only cycle.

This cycle will greatly enhance muscle building and strength gains compared to taking Anavar alone.

These are conservative doses and thus suitable for someone with little experience using anabolic steroids. However, such a cycle is not optimal for someone who’s never taken steroids before (in this case, a stack shouldn’t be used).

Anavar & Test Intermediate Cycle

This is the perfect follow-up cycle to the first Anavar and test cycle listed.

We find that intermediates who have previously taken Anavar and testosterone (in single cycles) frequently use this cycle.

Taking higher doses than those specified in this cycle greatly increases the risk of side effects without much more to show in the way of gains.

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Anavar and Andriol (Oral Test) Cycle

Not everyone is a fan of needles; thus, below is an oral cycle of Anavar and Testosterone (Andriol).

Andriol is the brand name for oral testosterone, also known as Testosterone Undecanoate . For many, this is a more convenient method of administering testosterone compared to injections.

The downside to oral testosterone is that it’s very expensive compared to injectable testosterone. When you factor in the price of Anavar, this will make for a very expensive cycle (costing a few hundred dollars plus).

However, for those who want maximum gains (when taking orals) with as little risk as possible, this is it.

Generally, we find orals to be very liver toxic; however, Anavar and Andriol are the exceptions. The kidneys help to metabolize Anavar, placing less stress on the liver, while long-term studies have shown Andriol to provide no hepatic strain .

A 10-year study of men using Andriol showed no notable increase in ALT and AST readings (markers of hepatotoxicity). Our anecdotal findings also correlate.

Important : When taking Andriol (Test Undecanoate), make sure you take the tablets with a high-fat snack or meal. Aim for at least 19 grams of fat with each dose. Research has shown that the biological availability of oral testosterone is roughly 50% lower when taken on an empty stomach ( 1 ).

3. Anavar and Winstrol Cycles

This makes for the ultimate cutting cycle , where users can expect rapid fat loss and significant muscle gains.

Anavar and Winstrol have many similarities, with both creating a dry and ripped look. Both are also oral steroids, used for stripping fat when cutting.

We have found Winstrol to be the more powerful of the two and not suitable for beginners  due to its toxicity. Thus, this cycle is only suitable for intermediate or advanced steroid users.

Users can expect Anavar’s usual mild side effects plus significant liver strain, testosterone suppression, and cardiovascular strain with the addition of Winstrol.

Due to the harshness of Winstrol, this cycle only lasts for 6 weeks, with advanced steroid users often extending this cycle to 8 weeks.

We see this type of cutting stack used by bodybuilders when prepping for a show, aggressively trying to reduce body fat and hang on to hard-earned muscle.

Winstrol isn’t generally recommended for women , because of its high risk of causing masculinization.

Thus, to reduce the chances of women losing their femininity, a very small dose of Winstrol is listed in the above cycle.

Despite a smaller dose, we find Winstrol still produces significant gains due to the sheer power of the steroid.

This cycle is not recommended for female beginners. Instead, it should only be utilized among women who have already undergone several steroid cycles or, at a minimum, have taken Anavar before.

We notice the risk of virilization increases when stacking Anavar and Winstrol together; thus, it should only be done in certain circumstances, i.e., preparing for a competition where the stakes are high. If women are simply trying to get in great shape, Anavar alone is sufficient.

4. Anavar and Clenbuterol Cycle

Clenbuterol is a beta2-antagonist (not a steroid) often used in medicine as an anti-asthma drug.

Clenbuterol is certainly a powerful addition to any cutting cycle due to its potent effects on metabolism. Clenbuterol has profound effects on the central nervous system, causing the body to produce more adrenaline. Consequently, the body heats up and enters a state of thermogenesis, accelerating fat loss (at rest).

Clenbuterol has also been shown to have potent anabolic effects in animals.

However, anecdotally, we do not see the same muscle-building effects in humans. Thus, an Anavar and Clenbuterol cycle will likely produce rapid fat loss with moderate increases in lean muscle and strength.

Due to the stimulative effects of Clenbuterol, energy levels and motivation are also likely to go through the roof.

Clenbuterol, like Anavar, is available in tablet form.

Considering that Clenbuterol is not a steroid, usual side effects such as gynecomastia, liver toxicity, acne, water retention, etc. are not an issue.

The main concern we have with Clenbuterol is cardiotoxicity, with it increasing a user’s heart rate significantly. Thus, it’s recommended to keep cycles short and to avoid taking Clen if your cardiovascular health is less than optimal.

Anavar and Clenbuterol Cycles For Men

As shown below, Clenbuterol is cycled in increments (by increasing the dose slowly every few days until hitting a maximum dose). This is done for a couple of reasons.

Firstly, a person can gauge their sensitivity to Clen by starting on a low dose and building up slowly. Starting on a high dose too soon may result in harsh side effects such as shaking, insomnia, and a racing heartbeat.

Secondly, we find that people build a tolerance to Clenbuterol very quickly; thus, an incremental dosing strategy can help users continue burning fat all the way throughout their cycle. This sample cycle lasts 4 weeks; no Clenbuterol cycle should extend beyond 6 weeks. After this time, the body’s temperature drops back down to its normal range, signifying a halt in thermogenesis (and thus fat loss).

The Anavar dose (20mg) lasts for 8 weeks. This dose is optimal for someone who’s already taken Anavar (or other steroids).

Anavar and Clenbuterol Cycles For Women

Clenbuterol is a suitable drug for women, as it doesn’t produce virilization side effects.

Unlike with steroids, a woman’s dose of Clen is typically similar to a man’s. Women produce a fraction of the testosterone a man produces; thus, a smaller dose of exogenous testosterone is needed to mimic the same effects.

In Clenbuterol’s case, because it doesn’t affect testosterone but instead the central nervous system, women often take an identical dose as men.

The Anavar dose below reflects a cautious dose for women that would be suitable for beginners. A higher dose of Anavar may be taken for more experienced users, starting at 10mg per day.

Anavar Cycle FAQ

Do you need to run a pct.

Anavar is a mild steroid, so running a PCT (post-cycle therapy) isn’t as essential as it is optional.

In our experience, Anavar does not shut down testosterone levels completely. Instead, they will become suppressed and take several weeks to recover to optimal levels. We have found that implementing a PCT can significantly speed up this process.

During this time of recovery, users may feel tired, have a low mood, and have a weakened libido post-cycle. Such after-effects aren’t just related to men but also to women.

This is because steroids also have a powerful effect on women’s hormones, with their endogenous testosterone levels getting sapped. Although women have far less testosterone compared to men, it remains an important hormone in their body chemistry. Women at our clinic often report a mild ‘crash’ from Anavar post-cycle.

An aggressive PCT is not required after an Anavar-only cycle . We have had success with men taking Nolvadex (Tamoxifen) or Clomid (Clomiphene) to help recover their testosterone production. This is more than sufficient.

• Nolvadex should be dosed at 40mg per day for 45 days, with 2 x 20mg pills taken daily.
• Clomid should be dosed at 100mg per day for 30 days, with 2 x 50mg pills taken daily.

Users should start their PCT approximately 57 hours after the last dose of Anavar. This is the estimated time that Anavar will fully clear out of the body.

You can work out when a steroid leaves the body by using the following equation: 5.5 x the half-life .

Anavar’s half-life is 9.4–10.4 hours .

Is a Liver Support Supplement Needed on Anavar?

We have not found Anavar to pose a serious risk to the liver when taken in sensible doses or cycles. Thus, users often take Anavar without a liver support supplement.

However, for those wanting maximum protection, TUDCA may be taken, which we have seen reduce oxidative stress on the internal organ. Clinical research has also shown TUDCA to significantly lower ALT and AST liver values, with both of these being markers of liver strain or damage ( 2 ).

If Anavar is stacked with other hepatotoxic orals, such as Winstrol, Anadrol or Dianabol — a liver support supplement is essential.

“Can I Drink Alcohol With Anavar?”

Alcohol generally should be avoided when taking oral anabolic steroids, as it will exacerbate liver values. However, for most users who generally have a healthy liver, small amounts of alcohol are likely to be fine.

We have seen patients who have consumed high amounts of alcohol during oral cycles, and their ALT/AST levels only increased marginally above baseline. However, there are other patients who didn’t touch a drop of alcohol and yet experienced hepatic peliosis .

The only way to know if you can drink small to moderate amounts of alcohol on a cycle would be to get your ALT and AST levels checked during it.

It is important to note that alcohol increases cortisol; thus, it will blunt Anavar’s fat-burning effects, so this also needs to be considered.

If you notice your skin or eyes turn a yellow color and you experience pain or discomfort in the abdominal region, immediately stop taking Anavar (and any other steroids) and visit your doctor.

Where Do People Buy Anavar?

Anavar is illegal to use for bodybuilding purposes due to the Anabolic Steroids Control Act in 1990 ( 3 ). Therefore, bodybuilders purchase Anavar via the black market if they want to cycle it.

In real-life terms, buying from the black market means buying from a person who deals drugs or a website that claims to sell Anavar.

Consequently, some bodybuilders are using legal Anavar alternatives , such as Anvarol , which mimics the same fat-burning and anabolic effects in the body as Anavar. However, we have not seen Anvarol cause any side effects, so you won’t experience any testosterone suppression or raised cholesterol levels like you would with Anavar ( 5 ).

We recommend Anvarol (legal Anavar), ensuring our readers stay within the confines of the law and make gains safely. 

Co Authors :

For TRT inquiries, please contact Dr. O’Connor via the Anabolic Doc App.

Over the last 20 years, Dr. O’Connor has successfully treated thousands of men who have taken anabolic steroids, SARMs, and other PEDs, giving him first-hand experience of their effects. Board-certified MD since 2005.

(1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170073/

(2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134868/

(3) https://nida.nih.gov/publications/research-reports/steroids-other-appearance-performance-enhancing-drugs-apeds/what-history-anabolic-steroid-use#:~:text=Congress%20passed%20the%20Anabolic%20Steroid,dozen%20drugs%20as%20controlled%20substances.

(4) https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-022-13734-4

(5) https://pubmed.ncbi.nlm.nih.gov/7350219/

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• Testosterone Replacement Therapy

Blasting and Cruising on TRT

• Thread starter Snake Plisken
• Start date Oct 4, 2013

Snake Plisken

• Oct 4, 2013

If your not prone to gyno that is great. I would still have an AI on hand. You really need blood work to determine your E levels or Progesterone if your on tren. At those doses I don't get gyno but go higher on the doses and I do.  

sleepincivic

Me personally, I blast and cruise also cause of trt and I would absolutely have an ai onhand with any blast. Im prone to e levels going high up. Just like jas101 said labs.. labs tell all. Just remember it's easier to keep e levels in check then trying to get them to get back in check.  

• Oct 5, 2013

Ok, thanks for the response. I appreciate the help.  

1tuffcookie

I'm thinking of TRT myself at 46. I'm on my 11th week of a 12 week test/tren/whinny cycle right now and my question is: Should I go right into a TRT protocal of 250mg test a week or should i get some bloodwork done to determine where my levels are now compared to my baseline??  

Do ypu know what your levels are naturally? You said that you on a cycle right now. I myself go straight from a cycle back to my trt protocol. I mean if you know that your low naturally and have been for a while and have tried a restart for natural production then yes if it was me I would go right into a trt dosage.  

Also 250mg week is alot to start a trt dose. I personally am at 150 week and that keeps me right there at 950-1000 ng/dl. I also take an ai with trt because e will creep up on you even with a low dose of test. Best to do is start right around there for around 6 wwleeks and get labs to see where you stand.. with trt labs are your friend.  

I have to go back and dig out my baseline readings. If I did go trt it would be self imposed and not through a Dr. so in my state I would need a scrip every time. My Dr. knows I'm on AAS and like most Dr. frowns on it....  

Thats basically what I do. Im 32 with a baseline t of 142ng/dl. When I blast I usuall run test c at 600-800mg pw depending on the other compounds. Then after last blast pin I start my trt protocal at 200mg pw testc and my normal ai back.  

I've been wondering about blast and cruise as well. I'm on TRT @ 200/week Test C (well, I was until I dropped off to try and get the wife preg). Once I get back on, I figure I'll go 10-12weeks of normal TRT dose to get back in the groove and then do a 10-12 week blast. I'm trying to decide what I want to blast with... Should I got 500/week of Test C, or should I throw in some other compounds? I had no issues with Test C doing TRT, but this would technically be my 1st true "cycle" so the usual advice is to go pure test. Any advice/suggestions?  

• Oct 6, 2013

Brother, that is awesome advice, thank you very much. I was looking for some specificity. So, let me just understand: If you were in my shoes, and were about to do a 12 week, 500mg test/100mg anavar last 8 week cycle, you would take 1 mg of anastrozole EOD for the duration of the 12 weeks? Assuming no sides are noticed, can I then just go back to my usual 200mg/week test cyp. proctocol? Again, don't care about fertility or ball size. Should I have nolvadex on hand just in case? Sorry for all the questions, but I am getting alot of mixed information (outside sources). Thanks, just trying to figure this out before I leap.  

OK so my baseline test is 20.8.... Hmmmmm decisions decisions... ok guys input please...  

• Oct 9, 2013

this ^  

Snake Plisken said: Brother, that is awesome advice, thank you very much. I was looking for some specificity. So, let me just understand: If you were in my shoes, and were about to do a 12 week, 500mg test/100mg anavar last 8 week cycle, you would take 1 mg of anastrozole EOD for the duration of the 12 weeks? Assuming no sides are noticed, can I then just go back to my usual 200mg/week test cyp. proctocol? Again, don't care about fertility or ball size. Should I have nolvadex on hand just in case? Sorry for all the questions, but I am getting alot of mixed information (outside sources). Thanks, just trying to figure this out before I leap. Click to expand...

It helps alot, thank you very much. One last question, in your opinion, is arimidex (dosed at approx. 1mg eod) and aromasin (dosed at approx 12.5mg ed) as good as anastrozole? I understand the need for labs, but is there real tangible difference between the three for guys in our shoes?  

• Oct 10, 2013

Snake Plisken said: It helps alot, thank you very much. One last question, in your opinion, is arimidex (dosed at approx. 1mg eod) and aromasin (dosed at approx 12.5mg ed) as good as anastrozole? I understand the need for labs, but is there real tangible difference between the three for guys in our shoes? Click to expand...

Thanks again for answering all my questions. I feel much more educated. I appreciate it.  

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Blast + Cruise Guys: Cruise Length/Dose?

Hey fellas got a few questions if you could all give me your opinions that’d be great.

How long do you cruise for, before blasting again.

When you cruise do you cruise at your trt dose or do you give yourself a lil bit more?

I know there is significant research on steroids and cardiac hypertrophy, is this something being on trt for many years can cause?

I know I post alot of threads just trying to soak up all the knowledgey goodness

Depends on the goal and person. For me my cruises are during what I consider my off season. To clarify my on season is 12 weeks before a meet. So if I do a meet every 6 months then my cruise is about 12 weeks then blast 12 weeks. If I compete 3 times a year my cruises are only 4 weeks long. Last year I compete every 3 months lol so I pretty much blast all year.

Dose for cruise is 200mg Test E and 200mg of Tren E. My blast vary on compounds but on average.

12 weeks out of meet 1000mg of Test 750mg of Tren 500mg of Eq or Deca

6 weeks out Same as above Add in 50-100mg of 2 different orals weight class goal dictates which ones.

I’ll let smarter people answer the last question

[quote]Reed wrote: Depends on the goal and person.[/quote]

This exactly. My cruises are planned around periods where I have an extended vacation, which is usually 4 times a week. Right now I’m on a 28 week blast, followed by a 4 week cruise, then a 12 week blast, then I’ll come completely off for 2 months to let my body recover. Then back on. Usually it’s somewhere between 12-24 blast, 4 cruise, repeat.

fuck it just do BLAST BLAST, where each blast is higher than the last. cruising is a thing of the past

[quote]eatliftsleep wrote: fuck it just do BLAST BLAST, where each blast is higher than the last. cruising is a thing of the past[/quote]

Should really depend on your blood work.

Some guys stay on an oral all year long and their liver values stay within range. other guys can’t run anything for past 10 days.

Shadow Pro IIRC correctly recommends going off completely for a couple months of the year, every year. Do not perma-blast and cruise.

what’s the point in completely coming off if you’re on trt

Ok cool also I know you don’t use AI’s reed but do any of you other blokes run ai’s when cruising?

[quote]kenny-mccormick wrote: Ok cool also I know you don’t use AI’s reed but do any of you other blokes run ai’s when cruising?[/quote]

I do not, my estro stays in the 20’s for the most part. Definitely depends person to person though.

My Endo said I’m pritty estrogen dominant I don’t really understand what this means but on cycle I kept my adex to 0.25mg eod and the only sides I got was my acne got worse

Edit: I guess ill have to figure this out when I start trt and get my first lot of bloods done

[quote]kenny-mccormick wrote: Hey fellas got a few questions if you could all give me your opinions that’d be great.

I know I post alot of threads just trying to soak up all the knowledgey goodness[/quote]

Depends on your goals and how you manage unwanted sides from your cycles. Some people struggle with certain issues that may delay going back on another blast. I had bad E2 levels and took a bit of time to lower that before I even considered blasting again

Typically blasts and cruises are the same length from what I’ve heard but I think you can decide if you’re ready sooner or need more time

I personally believe in cruising at a normal TRT dose. I could be wrong but I wonder if you added 100mg/week to your cruise dose (which prob won’t do squat) that you might need to add 100mg/week more to your blast dose just to make sure you get the results you’re looking for on cycle

^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^

This is just theory and based on nothing so know it is just my opinion

I will be starting my 2nd blast Monday.

Weeks 1-14 Arimidex @ .5mg ED ( adj w bloodwork) Weeks 1-6 500mg Test Cyp Weeks 1-6 2500mg Deca Weeks 6-10 80mgs Anavar Weeks 7-10 600mg Test Cyp Weeks 7-8 300mg Deca

Weeks 14 and beyond - TRT dose

This will be a BIG blast for me! My last blast was 300mg/ week of just Test Cyp. I gained a bit better than 10lbs and only lost 3lbs the 3+ mos I’ve been cruising ( I diet a bit to lean out a bit so I feel like I still gained; I needed to get my E2 under control and shedding visceral fat seemed to make a HUGE difference)

I’m hoping to pack on 10lbs of solid muscle after this next cycle while getting even leaner

[quote]kenny-mccormick wrote: My Endo said I’m pritty estrogen dominant I don’t really understand what this means but on cycle I kept my adex to 0.25mg eod and the only sides I got was my acne got worse

Edit: I guess ill have to figure this out when I start trt and get my first lot of bloods done[/quote]

so he told you that you were estrogen dominant without seeing any bloodwork? sounds like a lot of endos to me, dumb as fuck, just get the script from him and know what bloodwork you need to get during each checkup and demand it, basically take your treatment into your own hands, all he is good for is the script for test and bloodwork. Maybe i’m wrong but it sounds like he is somewhat clueless

[quote]ToolManSam wrote:

I’m hoping to pack on 10lbs of solid muscle after this next cycle while getting even leaner [/quote]

that 2500 mg of deca was a typo right? lol

[quote]eatliftsleep wrote:

so he told you that you were estrogen dominant without seeing any bloodwork? sounds like a lot of endos to me, dumb as fuck, just get the script from him and know what bloodwork you need to get during each checkup and demand it, basically take your treatment into your own hands, all he is good for is the script for test and bloodwork. Maybe i’m wrong but it sounds like he is somewhat clueless [/quote] Yeah I got that feeling too when I was asking him questions a d he wasn’t really answering them trt is not a very big thing in Australia most endos deal with women’s menopause problems

that 2500 mg of deca was a typo right? lol [/quote]

Holy FUCK!!! I meant 25,000mg lol Yeah 250…I wonder what 2500 would do to your sex life

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Blast and Cruise

Blast and cruise is a new method of administering anabolic and androgenic steroids. Back in the days, nobody was blasting and cruising. That’s one of the biggest reasons why old school bodybuilders can’t even compare to today’s mass monsters. During the blast and cruise cycle protocol, people never stop using anabolic steroids.

They are blasting by using multiple anabolic steroids stacked together in a higher dosage for a period of about 8-16 weeks most commonly. Then they are cruising at a similar length of time with testosterone-only in a lower dosage. Then you’re blasting again. There are those who repeat this protocol for years.

The point is – you never stop administering anabolic and androgenic steroids. You always inject testosterone in order to keep high testosterone levels. Because you manage to constantly maintain testosterone levels high, you do not need a PCT plan. This also helps you avoid the physical and psychological withdrawal effects, as you don’t have as many fluctuations in hormone levels. This helps avoid muscle and strength loss, low sex drive, low mood, depression, and other symptoms specific to those coming off steroids.

Nonetheless, the blast and cruise cycle protocol increases the risks of harm. You continuously use steroids so the body might not be able to fully recover. The risk of permanent damage to the natural production of testosterone is high.

Therefore, blasting and cruising is more effective, but going back natural is safer.

Post Cycle Therapy

People who are running anabolic steroid cycles are very likely to experience withdrawal symptoms by not implementing a Post Cycle Therapy (PCT) plan. The PCT plan is there to help you reduce the excess levels of estrogens and restart the natural production of testosterone that gets inhibited due to the use of exogenous testosterone and other AAS.

• They help increase levels of testosterone and boost recovery. They recover your natural hormonal balance and this helps avoid low T symptoms after the cycle. That’s why the PCT plan is very important.

However, when you’re cruising – you do not stop using steroids. You continue running testosterone after the cycle. It replenishes the natural testosterone production that your body needs to properly function.

Instead of a PCT plan, after a cycle, you continue using testosterone but in a lower dosage. Some people use Testosterone in higher dosages (such as 500 mg/week), but this applies even more pressure to your body and might cause more damage to your organs.

Usually, a cruising protocol is – Testosterone alone at 100-200 mg/week. Most commonly, cruising lasts at least as long as you were blasting before you can start another blast. For example, 14 weeks blast = 14 weeks cruise before blasting again. However, the absolute minimum time for cruising before jumping on a blast again is 8 weeks. Nonetheless, that might not be enough time for your body to recover if you were blasting for longer than 8 weeks.

• Cruising is meant to help you recover from a blast. But it doesn’t put you on the same hormonal rollercoaster as you would with Post Cycle Therapy.

• The blasting period is basically the same cycle you would run for reaching your physique and performance enhancement goals. You use different anabolic steroids stacked together in higher dosages to gain muscle mass and strength.

Blasting usually lasts at least 8 weeks and up to 16 weeks. It’s commonly used in higher testosterone dosage and at least one other anabolic steroid. Professionals stack up to 4-5 steroids together. The exact dosage of each steroid and testosterone, the exact cycle length, and the number of steroids stacked depend on your experience, goals, weight and height, age, and other factors.

Blast and Cruise Cycle Protocol Example

Start your blast with Testosterone around 600-800 mg/week. Stack it with other steroids of your wish such as Deca Durabolin or Equipoise around 400-600 mg/week. Both used for a period of 12-14 weeks. Might add an oral steroid to kick start your blast/cycle. Such as Dianabol for the first 4-6 weeks at a dosage of 50 mg/day.

After the 12-14 weeks blast period, you go cruising for another 12-14 weeks period with testosterone alone, usually, in a dosage of around 100-200 mg/week. You’re then ready to start your next blast.

Buy Anabolic Steroids Online

Blast and Cruise Conclusion

Blasting and cruising is great for those who are competing and are serious about gains. It’s also great for those who do not plan to come off steroids or those who do not love Post Cycle Therapy . The blast and cruise cycle is great as it offers steady gains without losing muscles and strength, you won’t get hormonal imbalance from PCT and hence, no decline in physical and psychological health. Would help you reach more results and faster.

On the other hand – you’re committed to injections. You always need to inject on a weekly basis for very long periods. Moreover, it has a negative impact on your health. It might be riskier. Also, not everyone can come off blast and cruise cycle. Some permanently shut down natural testosterone production and they need to use testosterone injections for their entire life.

Regardless of what you choose – Iron-Daddy.to is here to help you. We would offer the best quality anabolic steroids ensuring you’ll get maximum results and the least side effects. You would also save money as we offer competitive prices for each AAS from each brand.

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Blast and cruise advice

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Hi all, Having come to the end of my latest cycle, I've made the tentative decision to continue using testosterone for the foreseeable future. Prior to outlining my latest cycle, I don't think i would have a given the idea of cruising much consideration, but from some advice i was given on here and the issues i have off cycle, I began looking into it and have drawn up a really basic plan as below: Test E 120 mg EW ( Mon/Wed/Fri) 250 iu HCG EW i'm considering adding HGH at some point, but don't really know how or if it would be beneficial. For anyone with experience or who blasts and cruises, what do you think of think of this cycle? Also - What effect does cruising have on your balls? On cycle regardless of how much HCG I run, my balls shrink to nothing. My test levels prior to starting my cycle was 640 ng/dl - so a part of me wonders if i should just run a PCT and wait until my natty test levels are tanked before I cruise. The primary reason I want to blast and cruise is to maintain my size. Off cycle is a constant struggle to hold onto the weight my body doesn't seem to like or want. As a natural ectomorph, i understand that surpassing my genetic limit is a factor. One issue I have is that I'm now out of gear and awaiting my order, and due to the current worldwide situation, it's taking a lot longer than usual, so as a result I haven't pinned in nearly two weeks. I'm hoping it'll turn up this week and wondered if perhaps the first pin should be a little higher due to depleted test levels? The only thing i'm using is Proviron at 50 mg ED, which is keeping me full and hard. gal_register('gal_100_7501967', '1', '1', '0', '0', '0'); gal_register('gal_116_7501967', '1', '1', '0', '0', '0'); gal_register('gal_77_7501967', '1', '1', '0', '0', '0');

Stock up on your future orders for extra gear. I would do 250IU HCG the MWF of your injections for 750IU Total Your HRT is pretty basic. I don't know your age but I would also consider adding in 100mg Deca per week (can split that up into MWF as well). It's quite inexpensive. I would also make sure you are supplementing with DHEA and Vitamin D3. HGH is certainly beneficial but it has in my opinion the worst mileage relative to the price. For the price of 1 month of HGH you could use the same money and invest in MK677 + EQ + Deca + Anavar and get a lot farther gal_register('gal_78_7501968', '1', '1', '0', '0', '0'); gal_register('gal_100_7501968', '1', '1', '0', '0', '0'); gal_register('gal_87_7501968', '1', '1', '0', '0', '0');

I no longer check my inbox. If you PM me I will not reply.

Originally Posted by Windex Stock up on your future orders for extra gear. I would do 250IU HCG the MWF of your injections for 750IU Total Your HRT is pretty basic. I don't know your age but I would also consider adding in 100mg Deca per week (can split that up into MWF as well). It's quite inexpensive. I would also make sure you are supplementing with DHEA and Vitamin D3. HGH is certainly beneficial but it has in my opinion the worst mileage relative to the price. For the price of 1 month of HGH you could use the same money and invest in MK677 + EQ + Deca + Anavar and get a lot farther Yes, my cycle is really basic, but as this is new territory for me, I just want to be cautious, but saying that, if i decide to run nandrolone , would NPP be ok? Is there any added benefit to taking 750 IU HCG EW? gal_register('gal_89_7502291', '1', '1', '0', '0', '0'); gal_register('gal_100_7502291', '1', '1', '0', '0', '0'); gal_register('gal_87_7502291', '1', '1', '0', '0', '0');

Originally Posted by Lee_1978 Hi all, Having come to the end of my latest cycle, I've made the tentative decision to continue using testosterone for the foreseeable future. Prior to outlining my latest cycle, I don't think i would have a given the idea of cruising much consideration, but from some advice i was given on here and the issues i have off cycle, I began looking into it and have drawn up a really basic plan as below: Test E 120 mg EW ( Mon/Wed/Fri) 250 iu HCG EW i'm considering adding HGH at some point, but don't really know how or if it would be beneficial. For anyone with experience or who blasts and cruises, what do you think of think of this cycle? Also - What effect does cruising have on your balls? On cycle regardless of how much HCG I run, my balls shrink to nothing. My test levels prior to starting my cycle was 640 ng/dl - so a part of me wonders if i should just run a PCT and wait until my natty test levels are tanked before I cruise. The primary reason I want to blast and cruise is to maintain my size. Off cycle is a constant struggle to hold onto the weight my body doesn't seem to like or want. As a natural ectomorph, i understand that surpassing my genetic limit is a factor. One issue I have is that I'm now out of gear and awaiting my order, and due to the current worldwide situation, it's taking a lot longer than usual, so as a result I haven't pinned in nearly two weeks. I'm hoping it'll turn up this week and wondered if perhaps the first pin should be a little higher due to depleted test levels? The only thing i'm using is Proviron at 50 mg ED, which is keeping me full and hard. Here’s what I do: Testosterone Cypionate - 200mg per week Primobolan Enanthate - 200mg per week HCG - 500ius per week Optional: Nandrolone Decanoate - 100-200mg per week (Good for your joints) Trenbolone Enanthate - 100mg per week (I don’t recommend cruising on Tren , as one of the major points of a cruise is to give your androgen receptors a rest. However it’s a small dose, but enough to keep you hard and nasty looking if you should find yourself cruising at maintenance calories or a slight deficit.) gal_register('gal_209_7502292', '1', '1', '0', '0', '0'); gal_register('gal_89_7502292', '1', '1', '0', '0', '0'); gal_register('gal_100_7502292', '1', '1', '0', '0', '0'); gal_register('gal_114_7502292', '1', '1', '0', '0', '0'); gal_register('gal_123_7502292', '1', '1', '0', '0', '0'); gal_register('gal_127_7502292', '1', '1', '0', '0', '0'); gal_register('gal_128_7502292', '1', '1', '0', '0', '0'); gal_register('gal_77_7502292', '1', '1', '0', '0', '0');

Originally Posted by i_SLAM_cougars Here’s what I do: Testosterone Cypionate - 200mg per week Primobolan Enanthate - 200mg per week HCG - 500ius per week Optional: Nandrolone Decanoate - 100-200mg per week (Good for your joints) Trenbolone Enanthate - 100mg per week (I don’t recommend cruising on Tren, as one of the major points of a cruise is to give your androgen receptors a rest. However it’s a small dose, but enough to keep you hard and nasty looking if you should find yourself cruising at maintenance calories or a slight deficit.) Wow, that would be a cycle for me! What does the primo do for you while you cruise? gal_register('gal_209_7502312', '1', '1', '0', '0', '0'); gal_register('gal_89_7502312', '1', '1', '0', '0', '0'); gal_register('gal_100_7502312', '1', '1', '0', '0', '0'); gal_register('gal_114_7502312', '1', '1', '0', '0', '0'); gal_register('gal_123_7502312', '1', '1', '0', '0', '0');

Originally Posted by Lee_1978 Yes, my cycle is really basic, but as this is new territory for me, I just want to be cautious, but saying that, if i decide to run nandrolone , would NPP be ok? Is there any added benefit to taking 750 IU HCG EW? NPP would require every other day injections which would add confusion to your current protocol. You'd be better off using Deca and then NPP when you want to blast. gal_register('gal_89_7502314', '1', '1', '0', '0', '0'); gal_register('gal_87_7502314', '1', '1', '0', '0', '0');

Originally Posted by Lee_1978 Wow, that would be a cycle for me! What does the primo do for you while you cruise? Keeps protein synthesis sky high

Originally Posted by Windex NPP would require every other day injections which would add confusion to your current protocol. You'd be better off using Deca and then NPP when you want to blast. Cool. What dose would you use if running deca alongside test on a cruise? gal_register('gal_87_7503569', '1', '1', '0', '0', '0');

Originally Posted by Windex Stock up on your future orders for extra gear. I would do 250IU HCG the MWF of your injections for 750IU Total Your HRT is pretty basic. I don't know your age but I would also consider adding in 100mg Deca per week (can split that up into MWF as well). It's quite inexpensive. I would also make sure you are supplementing with DHEA and Vitamin D3. HGH is certainly beneficial but it has in my opinion the worst mileage relative to the price. For the price of 1 month of HGH you could use the same money and invest in MK677 + EQ + Deca + Anavar and get a lot farther Just realised you've answered my question about dosing deca. Isn't the point of a cruise about maintenance? Wouldn't it be better to save the EQ and Anavar for a blast? gal_register('gal_78_7503570', '1', '1', '0', '0', '0'); gal_register('gal_100_7503570', '1', '1', '0', '0', '0'); gal_register('gal_87_7503570', '1', '1', '0', '0', '0');

Originally Posted by Lee_1978 Just realised you've answered my question about dosing deca . Isn't the point of a cruise about maintenance? Wouldn't it be better to save the EQ and Anavar for a blast? Neither EQ or Anavar are androgenic -based compounds. Blasting works best with androgenic compounds in addition to increasing dose. At 200mg EQ per week or 20mg of Anavar a day you get tons of anabolic benefits without health side effects. gal_register('gal_78_7503574', '1', '1', '0', '0', '0'); gal_register('gal_119_7503574', '1', '1', '0', '0', '0'); gal_register('gal_229_7503574', '1', '1', '0', '0', '0'); gal_register('gal_87_7503574', '1', '1', '0', '0', '0');

If money is not a factor, theres no reason not to run hgh year round. I love that shit. It made me thicker and denser. On the flipside if you cannot commit to hgh theres no point in it. It takes years of use to REALLY see the size increase.

Originally Posted by Octaneforce If money is not a factor, theres no reason not to run hgh year round. I love that shit. It made me thicker and denser. On the flipside if you cannot commit to hgh theres no point in it. It takes years of use to REALLY see the size increase. Exactly - it is the barrier of entry when it comes to GH. MK677 seems to be the budget alternative though.

Originally Posted by Windex Exactly - it is the barrier of entry when it comes to GH. MK677 seems to be the budget alternative though. It's like the Walmart of GH, but works every time.

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Originally Posted by Windex Neither EQ or Anavar are androgenic -based compounds. Blasting works best with androgenic compounds in addition to increasing dose. At 200mg EQ per week or 20mg of Anavar a day you get tons of anabolic benefits without health side effects. Got it. I'm going to stick with deca and test for now and perhaps somewhere down the line I'll incorporate other compounds. gal_register('gal_78_7504160', '1', '1', '0', '0', '0'); gal_register('gal_229_7504160', '1', '1', '0', '0', '0'); gal_register('gal_87_7504160', '1', '1', '0', '0', '0');

Originally Posted by Windex Exactly - it is the barrier of entry when it comes to GH. MK677 seems to be the budget alternative though. I'm intrigued - one to read up on for sure.

Originally Posted by Lee_1978 Hi all, Having come to the end of my latest cycle, I've made the tentative decision to continue using testosterone for the foreseeable future. Prior to outlining my latest cycle, I don't think i would have a given the idea of cruising much consideration, but from some advice i was given on here and the issues i have off cycle, I began looking into it and have drawn up a really basic plan as below: Test E 120 mg EW ( Mon/Wed/Fri) 250 iu HCG EW i'm considering adding HGH at some point, but don't really know how or if it would be beneficial. For anyone with experience or who blasts and cruises, what do you think of think of this cycle? Also - What effect does cruising have on your balls? On cycle regardless of how much HCG I run, my balls shrink to nothing. Are you planning on staying on TRT for the rest of your life? You can recover after cruise but you are playing with fire if you stay on for extended periods of time. Regardless of HCG your still going to shut yourself down so your balls will still take a hit. If your worried about fertility I’d consider running a PCT now as you haven’t jabbed in a while and following this check your sperm so you have know your baseline and can freeze some as well. Then go back on and cruise if that’s what you want to do. My test levels prior to starting my cycle was 640 ng/dl - so a part of me wonders if i should just run a PCT and wait until my natty test levels are tanked before I cruise. The primary reason I want to blast and cruise is to maintain my size. Off cycle is a constant struggle to hold onto the weight my body doesn't seem to like or want. As a natural ectomorph, i understand that surpassing my genetic limit is a factor. It’s down to you man, if you understand the potential health risks and fertility isn’t a worry/you’ve frozen some sperm then go ahead! I started cruising (TRT = 150mg p/w, HCG 500IU 2x p/w) a couple of years ago and I love it, no dips in hormone levels gym performance is consistent... lots of benefits! One issue I have is that I'm now out of gear and awaiting my order, and due to the current worldwide situation, it's taking a lot longer than usual, so as a result I haven't pinned in nearly two weeks. I'm hoping it'll turn up this week and wondered if perhaps the first pin should be a little higher due to depleted test levels? The only thing i'm using is Proviron at 50 mg ED, which is keeping me full and hard. When your gear comes start with your planned TRT regimen (if you decide to go ahead), no need to shoot more. That’s your bigorexia brain kicking in... a few weeks taking nothing wont have much of an impact at all providing your eating well and training... ^^^ Hope this helps... gal_register('gal_100_7504734', '1', '1', '0', '0', '0'); gal_register('gal_116_7504734', '1', '1', '0', '0', '0'); gal_register('gal_77_7504734', '1', '1', '0', '0', '0');

Can you blast and cruise Anavar /primo ? if so Which one would you use if you could use either gal_register('gal_78_7504862', '1', '1', '0', '0', '0');

Originally Posted by SilverBack G's Can you blast and cruise Anavar/primo ? if so Which one would you use if you could use either Primo is fine as it is not known to be liver toxic. Anavar is one of the least liver toxic oral steroids , but they are all toxic to some degree. I would never run an oral year round, hell I don’t even run orals in my cycles. I think if you looked at two identical twins over 5 years and one took orals and the other didn’t, you wouldn’t know the difference. Orals just makes shit work faster but they don’t help you keep it once you’re off. gal_register('gal_189_7504880', '1', '1', '0', '0', '0'); gal_register('gal_78_7504880', '1', '1', '0', '0', '0');

I see, good to know thank you!

All in all i think its better to do a PCT. Why buff all the time?. Boring. Try to better training and diett. Add mk677. Learn how to get gympump wo the anabolics. So much efficient pre workout nuttrients. As Piana stated. Come off. Be in charge. Dont let your life and body be ruled by drugs. Ull be buff in two weeks next time. More mass u hold on to, less mass u gain next time because u dont wanna do crazy dosages. Sent fra min BLA-L29 via Tapatalk

Last edited by AR's King Silabolin; 04-13-2020 at 07:48 AM .

Originally Posted by AR's King Silabolin As Piana stated. Come off. Be in charge. Dont let your life and body be ruled by drugs. He should have taken his own advice....

Originally Posted by Test Monsterone Primo is fine as it is not known to be liver toxic. Anavar is one of the least liver toxic oral steroids, but they are all toxic to some degree. I would never run an oral year round, hell I don’t even run orals in my cycles. I think if you looked at two identical twins over 5 years and one took orals and the other didn’t, you wouldn’t know the difference. Orals just makes shit work faster but they don’t help you keep it once you’re off. Anavar was created in part for people with failing livers. Liver toxicity and Kidney Renal strain are the 2 most misunderstood organs with respect to AAS. I have a colleague that's been on Therapeutic Anavar for the last 5 years and has a better lipid profile than 99% of Americans walking around. I don't know where you got the idea that anything from orals isn't maintainable but that's simply not true. Just because the water weight disappears when you stop taking Dbol doesn't mean you didn't create muscular hypertrophy while on due to lifting heavier. gal_register('gal_78_7505045', '1', '1', '0', '0', '0'); gal_register('gal_91_7505045', '1', '1', '0', '0', '0');

Last edited by Windex; 04-13-2020 at 11:25 AM .

Originally Posted by kelkel He should have taken his own advice.... He should have stayed off the blow at 300 pounds

Originally Posted by kelkel He should have taken his own advice.... Stil, its a good advice. Sent fra min BLA-L29 via Tapatalk

Originally Posted by i_SLAM_cougars He should have stayed off the blow at 300 pounds Not necessarely. But when u in a periode of your life use heavy doses of HGH straight for 15 years and get addicted to stims later on, ull run into problems later, roidblows or not. Sent fra min BLA-L29 via Tapatalk

Originally Posted by i_SLAM_cougars He should have stayed off the blow at 300 pounds Shhh it was pre-workout powder.

Originally Posted by Windex Anavar was created in part for people with failing livers. Liver toxicity and Kidney Renal strain are the 2 most misunderstood organs with respect to AAS. I have a colleague that's been on Therapeutic Anavar for the last 5 years and has a better lipid profile than 99% of Americans walking around. I don't know where you got the idea that anything from orals isn't maintainable but that's simply not true. Just because the water weight disappears when you stop taking Dbol doesn't mean you didn't create muscular hypertrophy while on due to lifting heavier. I’m not saying that gains from orals are not maintainable. I’m saying that just because they help someone get to their goal faster through quicker absorption, water retention, etc., doesn’t mean it will improve one's physique in the long run. I think that people should aim to look the best they can at TRT doses, not at the peak of their cycles. To me, orals are like a turbo charger, in that yes it will make you go faster, but at the cost of wear and tear. Personally I’m not trying to hurry up and put on 10 lbs in 4 weeks. For what? If there is ANY chance of liver toxicity, I don’t want anything to do with it. Same with sarms . Chance of cancer? Fuck that. For what? 5 extra lbs you’ll probably lose right after the cycle is over. People on here are pretty wreckless with their protocols I believe. Steroid users in general are. I’m not trying to put my body at more risk than it needs to be, so orals to me are not worth it. I’m 33 years old, I trained 17 years naturally, why do I need to hurry up and add 10 lbs and also strain my liver. Maybe your friend doesn’t have liver problems, but all the studies show that anavar is hepatotoxic, so I’ll take those studies over someone’s anecdotal experience. gal_register('gal_78_7505125', '1', '1', '0', '0', '0'); gal_register('gal_165_7505125', '1', '1', '0', '0', '0'); gal_register('gal_141_7505125', '1', '1', '0', '0', '0');

Originally Posted by Test Monsterone Maybe your friend doesn’t have liver problems, but all the studies show that anavar is hepatotoxic, so I’ll take those studies over someone’s anecdotal experience. Var may be hepatotoxic in larger doses (to some) but I don't recall studies showing negative responses to low dose therapy. It's a healing agent even used low dose and long term in children.

Originally Posted by Eduke93 ^^^ Hope this helps... Great advice. I gave no fertility issues or concerns about freezing sperm. Have toy had a 'break' since starting cruising?

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Harm Reduction in Male Patients Actively Using Anabolic Androgenic Steroids (AAS) and Performance-Enhancing Drugs (PEDs): a Review

Alex k. bonnecaze.

1 Dept of Internal Medicine, Section on Endocrinology and Metabolism, Wake Forest University School of Medicine, Winston-Salem, NC USA

Thomas O’Connor

2 Dept of Internal Medicine, University of Connecticut School of Medicine, Farmington, CT USA

Cynthia A. Burns

Anabolic androgenic steroid (AAS) and performance-enhancing drug (PED) use is a prevalent medical issue, especially among men, with an estimated 2.9–4 million Americans using AAS in their lifetime. Prior studies of AAS use reveal an association with polycythemia, dyslipidemia, infertility, hypertension, left ventricular hypertrophy, and multiple behavioral disorders. AAS withdrawal syndrome, a state of depression, anhedonia, and sexual dysfunction after discontinuing AAS use, is a common barrier to successful cessation. Clinical resources for these patients and training of physicians on management of the patient using AAS are limited. Many men are hesitant to seek traditional medical care due to fear of judgment and lack of confidence in physician knowledge base regarding AAS. While proposed approaches to weaning patients off AAS are published, guidance on harm reduction for actively using patients remains sparse. Medical education regarding the management of AAS use disorder is paramount to improving care of this currently underserved patient population. Management of these patients must be non-judgmental and focus on patient education, harm reduction, and support for cessation. The approach to harm reduction should be guided by the specific AAS/PEDs used.

INTRODUCTION

Anabolic androgenic steroids (AAS) and performance-enhancing drugs (PEDs) represent multiple classes of compounds used to enhance one’s physique and/or improve physical performance. These include testosterone esters, synthetic androgens, aromatase inhibitors (AIs), selective estrogen receptor modulators (SERMs), selective androgen receptor modulators (SARMs), human growth hormone (hGH), fat-burning compounds, and myriad other compounds. The use of AAS has become widespread in the USA, with an estimated 2.9–4 million Americans using AAS at some point in their lifetime. 1 Worldwide, the lifetime prevalence of AAS use is estimated at 1–5%. 2 Several case series of male gym attendees found the prevalence of AAS use to be 15–30% in this population. 3 – 5 While AAS use is often associated with professional athletics, the majority of adults using AAS are non-professionals taking these compounds recreationally. 4 , 6 , 7 Despite widely reported cardiovascular, reproductive, hematologic, and neuropsychiatric effects described with these agents, there exist no guidelines or evidence-based harm reduction approaches to men actively using AAS.

It is estimated that over 98% of those using AAS are male. 1 These compounds have become readily available through illicit internet sources. 8 Men are commonly motivated to use AAS to improve their muscularity and strength. 7 An increasing societal emphasis on body image is believed to have contributed to increasing AAS use among men. 9 , 10 Many of these men may be prone to developing muscle dysmorphia, a pathologic pre-occupation with muscularity and body image that may impair quality of life. 8 , 10 AAS use has also been correlated with a history of poor self-esteem, depression, suicidality, and previously experienced physical or sexual abuse. 11 – 13

Common consequences of AAS/PED use include dyslipidemia, hypertension, left ventricular hypertrophy (LVH), arrhythmia, atherosclerosis, polycythemia and thrombosis, infertility, endocrine dysfunction, tendon rupture, and sexual dysfunction. 6 , 14 – 18 Those attempting to discontinue AAS use often experience AAS withdrawal syndrome, a state of depression, anhedonia, and sexual dysfunction which challenges prolonged cessation. 6 The lack of long-term data, medical education, and national initiatives addressing AAS use is highlighted in several recent reviews, stressing the need for swift action to prevent the worsening of this growing issue. 2 , 8 With limited public health resources available to men using AAS, 6 and general distrust of clinicians among many of these patients, 19 men often rely on other men using AAS and online sources for advice regarding use and procurement. 7 , 20

A major effect of extended AAS use is anabolic steroid-induced hypogonadism (ASIH), which refers to the disruption of the hypothalamic-pituitary-testicular (HPT) axis from prolonged exposure to supraphysiologic doses of testosterone esters, synthetic androgens, and accessory performance–enhancing drugs. 21 Men using AAS often attempt to prevent ASIH by taking various compounds such as SERMs and hCG, an unproven strategy referred to as “post-cycle therapy” or “PCT.” ASIH is proving to be a significant cause of male hypogonadism, with 20.9% of 6033 hypogonadal men reporting prior AAS use in a recent retrospective study. 22 The development, degree, and duration of ASIH is highly dependent on factors such as age, dosages used, duration of use, and compounds used. 23

While several authors have addressed the proposed management of men ready to stop AAS use with symptomatic ASIH 2 , 23 , 24 (Table ​ (Table1), 1 ), harm reduction guidance for men actively using these agents remains limited. To begin, an example of a common clinical experience for the patient using AAS/PEDs is described to highlight the challenges faced by both clinician and patient. Next, the approach to caring for such patients, review of specific AAS/PED compounds, and strategies for harm reduction are described.

Proposed Methods for Transitioning Off AAS

Clinical Example

A 39-year-old man presents to his primary-care clinic to discuss having blood work checked. Vitals are notable for a blood pressure of 142/90 mmHg and a body mass index (BMI) of 31 kg/m 2 . On exam, he has above-average muscularity and mild acne. He hesitantly discloses he has been using steroids to improve his physique and describes his regimen (Table ​ (Table2). 2 ). He obtains the steroids from the internet and a friend at the gym helps him plan his “cycle.” He has concerns regarding his use and wants to make sure his liver function and blood counts are “okay.”

Example of 12-Week AAS/PED Regimen with 6-Week Post-cycle Therapy

*Taken pre-workout with ~75 g simple carbohydrates

The clinician discusses the dangers of AAS use and recommends he discontinue. The patient expresses multiple concerns with stopping, including concern over losing strength and muscularity. The clinician tells him “it is important for your health that you stop using. Why don’t you stop for a few weeks before we check labs?”

Frustrated with the lack of understanding and lack of assistance from his physician, he resorts to following advice of other men using AAS. Despite multiple attempts to wean his use, he struggles with severe depression from acute AAS withdrawal. Due to his prior experience with his healthcare provider, he continues to self-manage his care and rely on others using AAS rather than seeking medical care.

Initial Approach to Men Using AAS Seeking Healthcare

The presented vignette highlights a common situation: A concerned patient using AAS who is unsure how to best monitor his health, seeking guidance from a well-intentioned clinician with has limited experience in assisting such patients. While the patient did not state willingness to cease use, he demonstrated concern for his health by seeking care. His clinician intended to help, but unintentionally promoted preconceived beliefs the patient had regarding the healthcare system, ultimately discouraging him to seek further care.

A recent systematic review of AAS use found common reasons for seeking medical care were overall health concerns, blood test monitoring, and prescription substances. Help with discontinuing AAS use was not a top priority. 25 Clinicians should certainly discourage AAS use, but the initial interaction should serve to obtain a better understanding of why the patient is using AAS, what concerns they have, and why they are seeking care. Doing so in a non-judgmental and supportive manner is essential. Open-ended questions may reveal motivations of the patient, such as fertility or side effect avoidance. Identifying these factors creates opportunities to build rapport, minimize harm, and eventually progress to cessation.

Alternatively, no such motivation may be identified. In this situation, harm reduction labs may be even more useful. For example, identifying previously undiagnosed dyslipidemia or cardiac disease may serve as motivation for some patients to consider cessation. The following sections will provide background, side effects, and harm reduction strategies for commonly used AAS/PEDs.

ANABOLIC ANDROGENIC STEROIDS AND PERFORMANCE ENHANCING DRUGS OF MISUSE: (TABLES  3 AND ​ AND4 4 )

Overview of AAS/PEDs, Side Effects, and Proposed Harm Reduction Approach

Initial Treatment of Diagnosed Adverse Effects of AAS/PED Use

*Contraindicated in severe liver disease and unexplained transaminitis. We suggest these agents be avoided in men actively using hepatotoxic oral AAS

+ = Off label for the purpose of treated AI-induced bone loss in men

Injectable Androgenic Anabolic Steroids

Dating back to the 1950s, numerous injectable testosterone compounds were used by elite athletes for strength and muscle gain. By the 1980s, AAS were in use by the general public. 9 There are three main classes of AAS compounds: testosterone esters, 19-nortestosterone and related derivatives, and dihydrotestosterone (DHT) derivatives 26 , 27 (Table ​ (Table5). 5 ). Each class is believed to have somewhat unique anabolic and/or androgenic effects. 26

Classes of Injectable and Oral AAS

*Both oral and injectable forms utilized

The foundations of most AAS regimens are testosterone esters and synthetic testosterone compounds taken in supraphysiologic doses. Reported doses commonly range between 500 and 1000 mg of testosterone per week, 7 which is 5–10 times the accepted treatment dose for male hypogonadism. 28

It is common for men using AAS to utilize injectable AAS for 8–16 weeks at a time, often referred to as a “cycle”. 27 “Stacking” refers to the use of multiple AAS/PEDs during a cycle. A cycle is commonly followed by a period of weeks to months where users either decrease their AAS dose or abstain completely to allow recovery of their hypothalamic-pituitary-testicular (HPT) axis. 23 Additional AAS nomenclature is available in Table ​ Table6 6 .

Commonly Used AAS Nomenclature

Adverse Effects

Cardiovascular effects of AAS are the most frequently reported and have the highest quality of data supporting their association. A recent cross-sectional study of 86 males with over 2 years AAS exposure was found to have reduced left ventricular ejection fraction (LVEF), impaired diastolic relaxation, increased left ventricular mass, and higher volumes of coronary artery plaque compared to age-matched non-users. 15 Post-mortem studies revealed increased rates of cardiomegaly, left ventricular hypertrophy, and myocardial fibrosis compared to non-users. 29 – 31 Increases in LDL and decreases in HDL were supported by a meta-analysis examining 11 studies on dyslipidemia in men using AAS 14 ; the same study found an association with AAS use and atrial fibrillation and ventricular arrhythmia. Coronary artery calcium (CAC) testing of 14 male professional bodybuilders using AAS found that 7 patients had CAC scores greater than the 90th percentile expected for their age, 3 of which were under 40 years old. 32

AAS use has been shown to cause infertility and ASIH in retrospective studies. 17 Restoration of fertility and endogenous testosterone production is more likely in men who engaged in shorter (generally under a year) and less-extreme AAS use. 2 , 23 Estrogenic side effects are common due to the aromatization of exogenous androgens, causing issues such as gynecomastia. 33 Exogenous testosterone is also shown to accelerate the growth of existing metastatic prostate cancer. 34

A wide range of behavioral effects are reported with AAS use including impulsivity, hypomanic/manic symptoms, aggression, and anxiety. 6 , 35 Multiple retrospective and cross-sectional studies found an association of AAS use with concurrent illicit substance use disorder, and body image disorders such as muscle dysmorphia. 10 , 36 , 37 AAS withdrawal syndrome is reported in men abruptly stopping AAS use and involves significant symptoms of depression, libido dysfunction, and anhedonia. 2 , 6

Other notable adverse effects include dose-dependent erythropoiesis and polycythemia, 38 thrombosis, 16 development of focal segmental glomerular sclerosis (FSGS), 39 acute kidney injury (AKI), 40 and upper extremity tendon rupture. 18

Harm Reduction Strategies

Initial screening should include blood pressure assessment, review of family history of cardiovascular disease, lipid profile testing, a comprehensive metabolic panel, and electrocardiogram (ECG) testing. Hypertension and dyslipidemia should be treated according to national guidelines. Given the increased prevalence of LVH in this population, 14 we favor angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) for the treatment of hypertension. Obtaining a transthoracic echocardiogram (TTE) is reasonable if there is clinical concern for cardiac dysfunction, chronic AAS use (over 1 year), and/or strong family history of cardiovascular disease. CAC testing should also be considered if additional atherosclerotic cardiovascular disease (ASCVD) risk factors are identified.

We suggest prostate stimulating antigen (PSA) screening in this population the same way it is recommended in men receiving testosterone replacement therapy per Endocrine Society guidelines. 28 Screening involves assessing PSA in men aged 55–69 years old (or beginning at age 40 if high risk) in those agreeable to prostate cancer screening. Referral to urology is recommended in situations of abnormal prostate exam, PSA > 4 ng/mL, sudden worsening of lower urinary tract symptoms, or a confirmed PSA increase of greater than 1.4 ng/mL over a 12-month period. Testosterone levels with gonadotropins may be useful in quantifying the degree of androgen use and HPT-axis suppression, or if AAS use is suspected but uncertain.

Due to the high prevalence of behavior disorders and concurrent substance use, 13 , 36 , 37 we suggest early referral to a behavioral health specialist, ideally having experience regarding substance use disorders and body image disorders. The association between AAS use and increased psychological distress and impaired executive function 41 is one possibility as to why these issues are more frequently seen among this population.

Oral AAS/Pro-hormones

Oral AAS compounds, such as metandienone (Dianabol), oxandrolone (Anavar), and stanozolol (Winstrol) are commonly used in conjunction with injectable AAS during steroid cycles for added muscle size and strength benefits. 42 These agents gained popularity in the 1970s and continue to be common additions to user-designed AAS cycles. 27

Alkylated oral compounds are associated with hepatotoxicity due to the presence of the 17-methyl group, which prevents degradation by first-pass hepatic metabolism when dosed orally. 43

In addition to the approach advised for injectable AAS, obtaining liver function tests is of benefit due to the high prevalence of hepatotoxicity from oral alkylated AAS. Reviewing concurrent substances, medications, or supplements that may cause additional hepatic injury is advised.

Aromatase Inhibitors

AIs, such as anastrozole and letrozole, are used during an AAS cycle to minimize the conversion of testosterone to estradiol. This practice is done to minimize estrogenic side effects such as gynecomastia, 20 as well as to maximize the anabolic effects of AAS.

Previous randomized control trials of hypogonadal men have shown AI use in men results in decreased sexual function, increased adipose distribution, 44 and decreased bone mineral density. 44 , 45 While no cardiovascular event data exists for men using AIs, a retrospective study of over 13,000 female breast cancer patients using AIs showed an increased risk of valvular dysfunction, pericarditis, and dysrhythmia. 46

Obtaining yearly bone densitometry in patients using AIs is beneficial to screen for low bone mass; however, it should be discussed that insurance may not cover this cost. In men under 50 with low bone mass, but without an osteoporotic defining fracture, optimization of vitamin D levels and encouraged cessation of AI use are suggested. Bisphosphonates, or denosumab, could be considered in patients found to have osteoporosis. While no strong treatment data in this population exists, and such use would be off-label, these agents have been recommended in a joint position statement regarding management of AI-associated bone loss in post-menopausal women with hormone-sensitive breast cancer. 47 Discussing the sexual side effects of these agents may also benefit in promoting cessation.

Selective Estrogen Receptor Modulators

Commonly used SERMs include clomiphene citrate and tamoxifen. 7 Tamoxifen is used with AIs during heavy androgen use to limit estrogenic side effects. 20 , 23 Clomiphene citrate is used to assist with recovery of the hypothalamic-pituitary-testicular axis after heavy androgen use. 2 , 20 , 23 It is common for patients to take both clomiphene citrate and tamoxifen together as “post-cycle therapy” (PCT) after a cycle of AAS. 27

Clomiphene has successfully been used in men for treatment of hypogonadism for up to 7 years with no major adverse effects 48 ; however, prior systematic reviews suggested a potential correlation with thrombosis and ocular symptoms due to central retinal vein occlusion (CRVO). 49 , 50

We recommend no specific testing for SERM use; however, gathering user experiences regarding these agents may be useful for future cessation attempts. For example, men using AAS noting previous benefits from clomiphene use may be willing to attempt AAS cessation using such agents in a medically supervised manner.

Human Chorionic Gonadotropin

Human chorionic gonadotropin (hCG) is used to prevent testicular atrophy and preserve some degree of testicular function. 27 It is also utilized as PCT to expedite the recovery of testosterone production by Leydig cells. 20

The primary adverse effects of hCG include potential suppression of the HPT-axis and gynecomastia. 2

No specific testing is recommended, although this agent is rarely used in isolation.

Phosphodiesterase-5 Inhibitors

Men using AAS commonly use phosphodiesterase-5 (PDE-5) inhibitors (such as sildenafil or tadalafil) for both erectile dysfunction and improved blood flow to muscles during strength training. 51 Users may also combine these with popular workout supplements containing nitrate donors such as sodium nitrate. 52

A case series on misuse of these agents described severe hypotension, cardiovascular collapse, and death 52 ; combining PDE-5 inhibitors with nitrates is particularly dangerous given the potential for significant decreases in systolic blood pressure and coronary perfusion. 53

A review of the risks of these agents, particularly the danger of combining with nitrate compounds, should be discussed.

Fat Burning Compounds (T3, Clenbuterol, and DNP)

Commonly used compounds to reduce body fat include liothyronine (T3), clenbuterol, ephedrine, and occasionally, dinitrophenol (DNP). 27 , 42 T3 is commonly combined with the potent oral beta-2 agonist, clenbuterol. While clenbuterol is primarily used for its fat-burning properties, limited animal data has suggested it may also have an anabolic effect on skeletal muscle. 54 DNP is an organic uncoupling agent which allows proton leak across the inner mitochondrial membrane, creating heat as opposed to adenosine triphosphate (ATP). It was originally used in the 1930s as a breakthrough weight loss medication, before being banned in 1938.

Clenbuterol and T3 misuse has been associated with hypertension, arrhythmia, and myocardial ischemia in a retrospective review. 55 Patients using T3 will commonly have markedly suppressed TSH levels, suppressed T4 levels, and significantly elevated T3 levels. DNP has been associated with multiple deaths due to severe hyperthermia. 56 – 58

Screening for hypertension and ECG testing should be performed in all patients using these agents. TSH level with reflexive free T4 and total T3 levels should be obtained in patients using thyroid hormone as a PED.

Site Enhancement Oils

The use of injectable intramuscular oil (also called “site enhancement”) is utilized by some men using AAS, especially elite bodybuilders. 59 Site enhancement oil adds volume to the injected muscle, creating a “fuller” appearance. A popular formulation, known as synthol, consists of 85% oil suspended in an alcohol and lidocaine. 59 An additional compound, polymethylmethacrylate (PMMA), has been misused for cosmetic body sculpting. 60

Various complications, including injection site abscesses, systemic infection, cerebrovascular accident (CVA), intramuscular cystic disease, muscular fibrosis, vasculitis, and pulmonary emboli, have been described in case series. 59 , 61 Case reports of hypercalcemia secondary to 1,25-dihydroxyvitamin D production from granulomas formed at the areas of injection have also been described. 62 , 63

A CMP should be obtained to assess for hypercalcemia. Physical exam of injection sites should assess for potential infection, abscesses, or masses.

Insulin is used during phases of attempted weight gain due to insulin’s anabolic effects on protein and glycogen synthesis. Short-acting insulin is commonly administered pre-workout, post-workout, or both with simultaneous ingestion of simple carbohydrates. 42

Multiple cases of hypoglycemia in non-diabetic bodybuilders misusing insulin are reported, including one case of hypoglycemic coma. 64 – 66

A reasonable approach includes educating the patient on potential life-threatening hypoglycemic events, assessing a hemoglobin A1c, as well as providing glucometer and testing supplies to those who decline to stop using insulin. A hypoglycemia treatment plan should be provided.

Diuretics, such as furosemide and torsemide, are used 1–2 days prior to a physique competition to minimize subcutaneous water retention. Diuretic use occurs concurrently with extreme water and salt restriction, followed by a period of “salt loading.” Prior to competition, some competitors attempt to completely restrict sodium in addition to lowering water intake to less than 250 cc during the day of competition. 67

The combination of high-dose diuretics and electrolyte/water manipulation increases the risk of lethal electrolyte derangements such as hypokalemia. A case of hypokalemic paralysis during a bodybuilding competition was recently reported, in which the patient took 160 mg oral furosemide while restricting water intake. 68

Patients using diuretics while manipulating water and food intake are at the greatest risk of life-threatening electrolyte derangements. Potassium and magnesium levels should be assessed.

Human Growth Hormone and Related Peptides

Human growth hormone (hGH) is used during AAS cycles to enhance muscle hypertrophy and strength. 42 , 69 Doses vary significantly and generally range between 2 and 12 international units (IUs) daily. 27 , 42 Synthetic growth hormone–releasing hormone (GhRH) analogues, such as sermorelin, and IGF-1 are also used as a PEDs and sometimes prescribed by anti-aging clinics via compounding pharmacies. 27

Growth hormone excess has physiologic sequelae including hypertension, cardiomyopathy, increased malignancy risk, entrapment syndromes, and diabetes mellitus among many others, as is seen in patients with acromegaly. 70

Initial assessment should include screening for hypertension, hemoglobin a1c, assessment of cardiovascular risk factors, and ensuring patients are up to date with age-appropriate cancer screenings.

Dopamine Agonists

Dopamine agonists (DAs), such as cabergoline and bromocriptine, are occasionally taken by men using AAS to mitigate potential hyperprolactinemia. 27 While somewhat controversial, one animal study demonstrated that the use of the progestin-derived synthetic androgens nandrolone decanoate resulted in significant prolactin elevation. 71 Cabergoline is also used for enhanced sexual function and reduction of refractory period, which has been demonstrated in several randomized control studies. 72 , 73

Side effects of DAs include headaches, orthostasis, nausea, increased impulsivity, and occasionally cardiac valvular disease in chronic use. 74

Screening for and treating behavioral disorders are of importance given AAS alone has the potential to cause these issues. In rare situations patients have taken high-dose DAs for more than several years, a screening TTE is reasonable to exclude valvulopathy.

Selective Androgen Receptor Modulators

Selective androgen receptor modulators (SARMs) represent a relatively new class of non-steroidal compounds with tissue-specific agonist or antagonist activity at the androgen receptor. While the first SARM was originally developed in 1998, none has been FDA-approved. 75 Multiple professional athletes have been found using these compounds illegally in the past several years. 76 , 77 SARMs are typically purchased online as “research chemicals”. 78

While long-term data on these agents are not yet available, a clinical trial of one SARM was found to cause HDL suppression and abnormal liver function tests. 79 In a recent study involving chemical analysis of 44 products marketed online as SARMS, only 23 (52%) were found to contain SARMs, while many contained alkylated AAS compounds. 78

Given the substantial lack of data on these agents, we suggest a similar approach to patients using injectable AAS. Patients using SARMs should be educated on the lack of safety data.

AAS use among men continues to be a major healthcare issue that has not been adequately addressed by the medical community. The combination of easily procurable AAS/PEDs via internet sources and increased societal emphasis on idealistic muscular physiques across social media-fueled this health crisis. As with any substance use disorder, it is our duty as clinicians to provide empathetic, ethical, and supportive care to minimize self-harm until successful cessation is achieved. Limited formal undergraduate and graduate medical education on AAS use, distrust of clinicians among men using AAS, 19 and lack of evidence-based harm reduction approaches to this population have resulted in suboptimal care. It is a concerning disconnect between patients and clinicians which has yet to improve.

Many clinicians request these patients immediately stop AAS use; however, multiple physiologic and environmental factors challenge patients attempting to do so. Symptoms of depression, anhedonia, and sexual dysfunction due to AAS withdrawal syndrome increase the rate of recidivism in this population. 6 A recent case-controlled study suggested most men discontinuing AAS eventually recover endogenous testosterone production and spermatogenesis 80 ; however, being able to successfully abstain for long enough (months to years) to allow for HPT-axis recovery is a separate challenge altogether. Those using AAS likely associate with other men who use AAS and prioritize muscularity, strength, and body image. These ongoing environmental exposures and temptations in themselves serve as risk factors for recurring use. Given the many challenges of successful AAS cessation, it is paramount that harm minimization is prioritized to reduce the development of devastating health effects.

Harm reduction strategies are needed to assist the millions of men using these compounds who are currently unable or without the desire to quit. A recent review by de Ronde et al. 81 emphasizes the need for improved healthcare of men using AAS, but notes “It is the policy of our clinic not to offer routine health and blood checks to active users without health problems.” The authors discuss that reassuring results might encourage patients to continue using AAS. We believe this approach further propagates distrust of physicians, encourages continued reliance on other men using AAS for guidance, and reduces the likelihood of eventual cessation. A harm minimization approach to active AAS use is analogous to widely accepted public health practices such as screening active smokers for lung cancer and intravenous drug users for blood-borne viruses.

Compassionate care is paramount. It is essential that cessation of AAS use is routinely discussed with the patient. These regular discussions should be non-judgmental and caring, much like with smoking cessation. The authors strongly oppose the prescribing of medications with potential anabolic uses in patients who are currently using illicit AAS/PEDs. For example, we discourage prescribing an AI or SERM to a patient on illicit AAS who wishes to decrease his estrogen levels. In men who present with sexual dysfunction, not ready to work towards discontinuing AAS use, we discourage the use of PDE-5 inhibitors or other related treatments because clinician-supervised cessation of AAS improves/resolves this issue. We strongly support the screening and treatment of AAS-related cardiovascular conditions, behavioral disorders, and hematologic disorders to further reduce self-harm during AAS use. Once a patient acknowledges he is ready to discontinue AAS use, we currently favor a personalized approach as outlined in reviews by Anawalt 2 and Rahnema et al., 23 as no randomized control trials on this subject have been conducted.

We believe harm minimization would not only reduce adverse effects of AAS but also serve as a bridge to cessation. For example, many men using AAS are relatively young and have no prior health issues. A medical assessment revealing hypertension, dyslipidemia, and LVH may serve to have such a patient reconsider further use and consider cessation. In some men, the desire to continue AAS use will predominate despite the diagnosis of serious adverse effects. In these cases, the authors recommend continued close clinical surveillance in addition to prompt referral to appropriate behavioral health specialists. This will allow for continued health monitoring and management of adverse effects, while further building rapport and presenting ongoing opportunities to reconsider cessation.

LIMITATIONS

Most of the reviewed literature consisted of cross-control studies, retrospective reviews, and case series. The lack of randomized controlled data and limited prospective data are significant limitations. The guidance provided is based upon the current literature and the clinical experience of the authors.

CONCLUSIONS

A harm reduction approach, with a strong emphasis on reducing cardiovascular risk, should be taken with men actively using AAS who decline current cessation.

Acknowledgements

Alex K. Bonnecaze was involved with manuscript preparation and revision. Thomas O’Connor participated in manuscript review, revision, and editing. Cynthia Burns participated in formatting, editing, and manuscript revision.

Declarations

Thomas O’Connor owns and operates a private practice internal medicine clinic based out of Essex, CT, and has written a book on the adverse effects of AAS misuse. The authors have no other disclosures to declare.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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• Anabolic Steroids & Bodybuilding
• Anabolic Steroids

Blast and Cruise?

• Thread starter the small soldier
• Start date Apr 26, 2012

the small soldier

• Apr 26, 2012

Anyone here "stay on." I'm doing a natural powerlifting meet in July, but after that I'm thinking about going all out and doing a BB show. My aim would be blast and cruise for about a year. 12 weeks of teste 500 a week kick started with DBOL and finished with anavar, then cruising for 12 weeks on test E 150-200 a week, repeat for two cycles while bulking then repeat and cut using equipoise and test stacked, and finished with anavar. After the year I'd taper off the dose and run a very long PCT, I would of course run Adex and HCG throughout the entire year. Any thoughts?  

i would go a little heavier on the blasts myself and maybe shorten them a bit... we all have our own styles and there are lots of ways to work it out and that is just how i would do it... maybe add in a little tren on the blasts if you are cool with it... i dont like my tren after about 6 weeks myself so it fits the bill for me...  

moya said: i would go a little heavier on the blasts myself and maybe shorten them a bit... we all have our own styles and there are lots of ways to work it out and that is just how i would do it... maybe add in a little tren on the blasts if you are cool with it... i dont like my tren after about 6 weeks myself so it fits the bill for me... Click to expand...

joeblow12345

High end bro.

How old are you? How many cycles under your belt? If your 35+ then go for it. If you still have a good amount of natural test than cycling is a better choice imo. Personally When I hit 35-40 Im going to stay on forever. Sent from my DROID BIONIC using EliteFitness  

the small soldier said: I've never done tren so IDK. I can get it, but I'd like to run that solo with just a little test to see how my body responds. I always like to keep my options open though. How long would you blast for and what dosages? Click to expand...

joeblow12345 said: How old are you? How many cycles under your belt? If your 35+ then go for it. If you still have a good amount of natural test than cycling is a better choice imo. Personally When I hit 35-40 Im going to stay on forever. Sent from my DROID BIONIC using EliteFitness Click to expand...

moya said: 6-8 weeks, but i also didnt mention that i also prefer short esters, so that does make a difference... you could still implement tren in a blast, just up your test a bit and maybe 225/wk tren a, thats m,w,f pinning 75mg... i honestly think in as little as 3-4 weeks you can see signifigant changes on tren... next time i run it will just be a 3 week blast... for powerlifting you will LOVE tren... Click to expand...

Seattleborn206

I personally feel like if your an average gym rat and have no plans on ever stepping on stage then blast and cruise is out of the picture but if you plan on competing then it's a different story. If you truly want to compete at a high level and you know the risks and are prepared to go to the doctor for regular check ups and do everything to stay healthy then I see no problem with blast and cruise. I would just say DO YOUR RESEARCH and look at the pros and cons and really make sure this is something you want to do because bodybuilding and competing is mire then just a hobby it's a life style.  

Seattleborn206 said: I personally feel like if your an average gym rat and have no plans on ever stepping on stage then blast and cruise is out of the picture but if you plan on competing then it's a different story. If you truly want to compete at a high level and you know the risks and are prepared to go to the doctor for regular check ups and do everything to stay healthy then I see no problem with blast and cruise. I would just say DO YOUR RESEARCH and look at the pros and cons and really make sure this is something you want to do because bodybuilding and competing is mire then just a hobby it's a life style. Click to expand...

insanityapproved

If you feel like this is truly what you live for then yes bro go for it. I've been blasting and cruising for the past few years ever since I started competing at a top level. I quickly figured all of those guys do it and I have no chance of getting near the top if I don't do it aswell.  

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What Is The Blast and Cruise Protocol?

• Post author: ClickAndBuild
• Post published: August 12, 2020
• Post category: Anabolic Steroids
• Post comments: 0 Comments

If you’ve ever done a research on anabolic steroids then there’s a high chance that you have heard of some people on various different steroid forums or maybe a local gym guy using steroids who mentioned that they are going through a blast and cruise protocol.

Is quite obvious that if that’s the first time you’re hearing about this, you may not know what this means. When I firstly heard about this, I’ve done a research for understanding “ What is Blast and Cruise Protocol? ” and luckily, there’s a lot of information about blasting and cruising so I found out everything that I needed.

However, you have to do quite a lot of research taking in consideration that there’s a lot of information, some of which I found very useful, other I thought to be quite useless.

If you are not sure what does Blast and Cruise means, then below you would find the explanation. In this article, I try to offer you the easy explanation of this in a summarized form. So,

Blasting and Cruising protocol, basically, means that you do not come off steroids.

Yes, there are protocols in which you are not stopping to use steroids. When I firstly read about this, I thought there’s something wrong. I mean, lots of questions popped into my mind. As I’ve already had a good amount of knowledge on steroids, I knew that using them for longer periods than you should is very unhealthy.

But then I found out about blasting and cruising which means that people doing so, are basically running steroids the entire year round. So, let me explain it properly.

When a person is cruising, he is running a moderate dosage of testosterone as a base compound in order to put him in the high-end range of the testosterone levels. As we know, usually, during a normal Testosterone cycle, dosages usually start at about 400 mg a week and they can be up to like 1000 mg per week. The situation is different with blasting and cruising protocol.

Most of people who blast and cruise are running doses of about 100-200 mg of Testosterone (usually Enanthate, but it could be others) for a week during the cruise. Buy Testosterone here.

Lately, there are people who tried to cruise with something else other than testosterone during cruise, however, this is not actually considered a real cruise protocol.

So, we’ve ruled out what cruising means, but…

What’s the Blast?

A blast is when a person is using multiple compounds at the same time in order to put on a lot of size. Most of the people are going to go through only one or maximum 2 blasts in a year and that’s because the more you have, the more is the risk. With 1-2 per year, you greatly minimize the risks of affecting your health and receiving negative side effects.

The blasting is what puts your body under a lot of stress and makes it unhealthy if not used properly. The blast means that you are running multiple anabolic and androgenic steroids (AAS) for several months. Using lots of steroids together for long periods of time is stressful for your body.

As soon as the blasting is finished (there are different types of blasts), the anabolic steroid user is going to come back to his usual cruising dosage and would continue doing so until the user is being ready to go through his next blast. But usually this is lasting months. That’s why most of people won’t ever go over 2 blasts per year, while some do it only once yearly.

By doing so, the users are able to let their liver enzymes, their lipids as well as other functions (generally – their health) to return back to the normal state. The cruising is very important here because the testosterone levels that you run during the cruise is going to help the user to maintain the muscle mass that he was able to gain during the blasting protocol. This is the reason why cruising with other compounds than testosterone is not considered actual cruising.

Why would someone want to do so? Well, the main reason why blasting and cruising users decide to go through this protocol is to avoid the hormonal disturbance of the Post Cycle Therapy (PCT). Running a PCT, the user is basically receiving a hormonal rollercoaster and a lot of people wanted to stop it.

For example, a normal steroid cycle of approximately 14 or 16 weeks is very often being followed by a Post Cycle Therapy (PCT) and the PCT is usually done with some medicines like for example Nolvadex or Clomid (most often).

In the time that these products are used for helping the user to restore the natural abilities of the body to produce the testosterone, the compounds are also coming with negative side effects too and then again, the user has a misbalance in hormones during this.

Although many people are going through this very well, we are all different and that’s why, for some people it just doesn’t work well and they don’t want to go through it again. They think that this is not worth it going back through all the struggle of recovering and bouncing back again. And this means that they are going through both mental and physical changes.

With blasting and cruising, you do not need a PCT plan. The Post Cycle Therapy is made for you to avoid low testosterone levels, but with a Blasting and Cruising Protocol – the natural testosterone production is not a problem anymore due to the administration of testosterone every week of about 100 – 200 mg. Once again, that’s why is so important to run specifically testosterone during cruising, otherwise, that’s not a cruising. It basically means that the person is replacing the natural hormones.

Blast and Cruise Cycle

There are various different blasting and cruising cycles with many different compounds in many various dosages that you can administer. They all depend on various different factors such as your size, tolerance, ultimate goals and so on and so forth. However, below we would give you an example of a really good blast and cruise cycle which is quite common among many people.

You can find below what does it looks like a simple blast and cruise cycle example:

• 8 weeks of Testosterone for 150 mg per week (usually, Testosterone Enanthate).

Those are the weeks (roughly 2 months), which are considered as your “cruise” protocol. But then, this is being followed by blasting, for example:

• First 4 weeks with Dianabol 50 mg per day
• 14 weeks cycle length with Testosterone Enanthate 500 mg per week
• 14 weeks with Deca Durabolin 400 mg per week.

Buy Deca Durabolin here.

Once again, this is just an example of blasting, there are many others. For example, there are people who might want to change Dianabol for something else, usually that’s going to be either Superdrol or Anadrol. This is different based on your own preferences and final results desired. After you end your blasting cycle of 14 weeks, (but it can be shorter or longer, again, based on your needs and preferences), you need to switch back to 8 weeks of low dosage of 150 mg per week of Testosterone.

Basically, the cruising doesn’t change. You could use it for shorter or longer or higher or lower doses as well as various testosterone versions, but most often, it remains Testosterone Enanthate for 8 weeks 150 mg per week.

Most people change the blasting protocol that is different – steroid users can add Winstrol (Stanozolol) and Trenbolone to their blast if they want. Again, it depends on your personal preferences and ultimate goals.

Another thing to mention is the fact that there are some users who might even use SARMs for their cruise protocol, however, that’s not very popular because they are not as effective. SARMs are considered less suppressive than steroids (esterified testosterone) but they are far less effective too.

You could give a try to some of the most popular SARMs to use for a cruise like for example Ostarine and Cardarine and check how it works for you. Yet, most people don’t find them as good as Testosterone. In this situation, nothing else changes – as soon as those 8 weeks of cruising have finished, you should be able to start a new blast protocol, obviously, if you need and want it.

What I highly recommend is to do a blood work every once in a while. This way, you can check your lipids, liver as well as other organs in order to make sure that they function properly and you are healthy enough, as well as to make sure that the protocol doesn’t affect your health (and your organs, obviously) too much.

In addition to that, is very important for you to remember that this is a commitment, which means that you will need to inject absolutely every week in order to maintain your hormone levels at the higher end. Without doing so, you risk going into nasty symptoms.

Other than that, is highly recommended to have a healthy diet and generally – a healthy lifestyle with diet at point and proper exercise regime. Plus, getting yourself some cycle supporting products and supplements would be really helpful. This especially applies to blasting cycle when your body is put to much more stress. Dieting, exercising and using supplements would make sure that you remain healthy and you properly protect your organs.

For example, many oral steroids affect your liver in a bad way. In order to protect it, avoiding anything that affects your liver such as OTC medicines, alcohol consumption and various other factors is highly recommended. Using liver protecting supplements can greatly help too.

Another very important thing to keep in mind is that when you would want to come off your entire blast and cruise cycle, then that can be quite a hard process, since is hard to fully recover normally. This highly depends on how long you have been blasting and cruising too. Obviously – the longer you’ve been on your blasting and cruising cycle, then the harder is going to be to fully recover from it.

This is the reason why many people who are not doing it professionally, opt for shorter blasting and cruising cycles. Professionals, usually, go for longer blast and cruise cycles as they have enough experience and knowledge on how to do it properly and how to fully recover easier.

You might find online (on different steroid forums and blogs as well as other sources) various different strong protocols that are going to help you to recover back from a blast and cruise cycle.

Despite the fact that many of them are indeed helpful, we need to warn you to do a lot of research on this first, that’s because there have been situations when users did not fully recover from their blasting and cruising. In some instances, this can be unhealthy, but it does come with negative side effects (nasty symptoms).

Is very important for anyone to remember this when you consider to start the blasting and cruising protocol. While this can be super effective, is not meant for everyone. Only start one when you have enough experience with steroids and enough knowledge based on research you’ve previously done.

The Blast and Cruise Protocol, as almost anything in this life, comes with Pros and Cons. Here are 3 most obvious and biggest Pros and 3 most obvious and biggest Cons:

• Faster goals reach
• Steady gains without interruption
• No hormonal misbalance during PCT cycle
• You would require weekly injections for long time
• It may have a more negative impact on your health and organs
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Blast and Cruise protocols: Full overview on them and its benefits

• March 31, 2023

If you’ve ever done research on anabolic steroids, then there’s a high chance that you have heard of a blast and cruise protocol. 

If this is the first time of hearing about a blast and cruise, then you may not be sure what this means. There is a lot of information out there that can be daunting for people new to this topic 

Although there is a lot of good information out there, there is also a lot of bad information, so if you are looking to find some easy to understand information about blasting and cruising, then this article is for you.

Read more About Proviron Dose

Blasting and Cruising protocol, basically, means that you do not come off steroids.  

Yes, there are some users out there who do not fully come off steroids, this is what a blast and cruise is. When I first read about this, I thought there must something wrong, I mean, lots of questions popped into my mind. I already had a good amount of knowledge on steroids, so I knew that using them for extended periods wasn’t the healthiest idea, until I found out about blasting and cruising, essentially this means the user will be taking steroids year-round, let me explain it properly. 

So, for a regular Testosterone cycle, for example, the user would typically use a dose between 250-750mg per week for a cycle in the range of 10-16 weeks before coming off completely for around 8 weeks. When a person follows a blast and cruise protocol, however, this will look quite different. During the blast phase of this protocol, doses of Testosterone will be the same as a regular cycle, between 250-750mg for 10-16 weeks, but the difference comes after this period. Instead of coming of Testosterone and running a PCT, you will then enter your cruise period, during this time you will drop your dose of Testosterone to a level similar to a TRT dose, around 125-150mg per week. 

To summarise, a blast phase will be the same as a regular cycle, and the cruise phase will be instead of a PCT protocol, during this time it is typically advised to only run low doses of Testosterone, however low doses of a compound like Primobolan may also be used by some people.

Most users would continue to cruise until they are ready to go through their next blast, usually, this will last a few months. That’s why most people won’t ever go over 2 blasts per year, while some do it only once yearly. 

By doing so, the users are able to let their liver enzymes, lipids as well as other functions (generally – their health) return back to a normal state. The cruising is very important here because the testosterone levels that you run during the cruise are going to help the user to maintain the muscle mass that he was able to gain during the blast protocol.

Why would someone want to do so? Well, the main reason why blasting and cruising users decide to go through this protocol is to avoid the potential hormonal imbalances caused by Post Cycle Therapy (PCT). Running a PCT, the user is basically risking hormonal imbalances as the body tries to recover. 

For example, a normal steroid cycle of approximately 14 or 16 weeks is often followed by a Post Cycle Therapy (PCT), and compounds like Nolvadex, Clomid or Proviron for PCT are used.  

During the time that these products are used for helping the user restore the natural abilities of the body to produce testosterone, the compounds also come with potential negative side effects too, and then again, the user has an imbalance in hormones during this. 

Although most users will go through their PCT with no issues, we are all different and that’s why for some people it just doesn’t work well and they don’t want to go through it. They think that this is not worth it going back through all the struggle of recovering and bouncing back again. And this means that they are going through both mental and physical changes. 

With blasting and cruising, you do not need a PCT plan. The Post Cycle Therapy is made for you to avoid low testosterone levels, but with a Blast and Cruise Protocol – the natural testosterone production is not a problem anymore due to the administration of testosterone every week of about 125 – 150 mg.

Read More About Deca Durabolin dose

What’s the Blast?

A blast is when a person is using multiple compounds at the same time in order to put on a lot of size. Most of the people are going to go through only one or maximum 2 blasts in a year and that’s because the more you have, the more is the risk. With 1-2 per year, you greatly minimize the risks of affecting your health and receiving negative side effects.

The blasting is what puts your body under a lot of stress and makes it unhealthy if not used properly. The blast means that you are running multiple anabolic and androgenic steroids (AAS) for several months. Using lots of steroids together for long periods of time is stressful for your body.

As soon as the blasting is finished (there are different types of blasts), the anabolic steroid user is going to come back to his usual cruising dosage and would continue doing so until the user is being ready to go through his next blast. But usually this is lasting months. That’s why most of people won’t ever go over 2 blasts per year, while some do it only once yearly.

By doing so, the users are able to let their liver enzymes, their lipids as well as other functions (generally – their health) to return back to the normal state. The cruising is very important here because the testosterone levels that you run during the cruise is going to help the user to maintain the muscle mass that he was able to gain during the blasting protocol. This is the reason why cruising with other compounds than testosterone is not considered actual cruising.

Why would someone want to do so? Well, the main reason why blasting and cruising users decide to go through this protocol is to avoid the hormonal disturbance of the Post Cycle Therapy (PCT). Running a PCT, the user is basically receiving a hormonal rollercoaster and a lot of people wanted to stop it.

For example, a normal steroid cycle of approximately 14 or 16 weeks is very often being followed by a Post Cycle Therapy (PCT) and the PCT is usually done with some medicines like for example Nolvadex or Clomid (most often).

In the time that these products are used for helping the user to restore the natural abilities of the body to produce the testosterone, the compounds are also coming with negative side effects too and then again, the user has a misbalance in hormones during this.

Although many people are going through this very well, we are all different and that’s why, for some people it just doesn’t work well and they don’t want to go through it again. They think that this is not worth it going back through all the struggle of recovering and bouncing back again. And this means that they are going through both mental and physical changes.

With blasting and cruising, you do not need a PCT plan. The Post Cycle Therapy is made for you to avoid low testosterone levels, but with a Blasting and Cruising Protocol – the natural testosterone production is not a problem anymore due to the administration of testosterone every week of about 100 – 200 mg. Once again, that’s why is so important to run specifically testosterone during cruising, otherwise, that’s not a cruising. It basically means that the person is replacing the natural hormones.

Blast and Cruise Protocol (doses and cycle logs) 

There are multiple blast and cruise cycles with many different compounds in various dosages that you can administer. They all depend on several different factors such as your size, tolerance, ultimate goals, and so on and so forth. However, below we would give you an example of a really good blast and cruise cycle which is quite common among many people. 

You can find below what it looks like in a simple blast and cruise cycle example:

• 8 weeks of Testosterone for 150 mg per week (usually, Testosterone Enanthate). 

Those are the weeks (roughly 2 months), which are considered your “cruise” protocol. But then, this is followed by blasting, for example: 

• First 4 weeks with Dianabol 50 mg per day 
• 14 weeks cycle length with Testosterone Enanthate 500 mg per week 
• 14 weeks with Deca Durabolin 400 mg per week. 

Once again, this is just an example of blasting, there are many others. For example, there are people who might want to change Dianabol for something else, usually, that’s going to be either Superdrol or Anadrol. This is different based on your own preferences and the final results desired. After you end your blasting cycle of 14 weeks, (this can be shorter or longer, again, based on your needs and preferences), you need to switch back to 8 weeks of low dosage of 125 – 150 mg per week of Testosterone.

Basically, the cruising doesn’t change. You could use it for shorter or longer or higher or lower doses as well as various testosterone versions, but most often, it remains Testosterone Enanthate for 8 weeks at 125 – 150 mg per week.

Most people change the blasting protocol – steroid users can add Winstrol (Stanozolol) and Trenbolone to their blast if they want. Again, it depends on your personal preferences and goals.

What I highly recommend is to do blood work every 3 months or so, this way, you can check your lipids, liver as well as other organs in order to make sure that they function properly and you are healthy enough, as well as to make sure that the protocol doesn’t affect your health (and your organs, obviously) too much.

In addition to that, is very important for you to remember that this is a commitment, which means that you will need to inject absolutely every week in order to maintain your hormone levels at the higher end. Without doing so, you risk the chance of side effects. 

Other than that, is highly recommended to have a healthy diet and generally – a healthy lifestyle with a balanced nutrient-dense diet and proper exercise regime. Find out the best steroids for CrossFit , weightlifting, and other types of sport.

It is also highly recommended to get yourself some cycle-supporting products and supplements. This especially applies to the blasting cycle when your body is put under much more stress. Dieting, exercising regularly, and using supplements would make sure that you remain as healthy as possible and that you properly protect your organs. 

For example, many oral steroids affect your liver in a bad way. In order to protect it, avoiding anything that affects your liver such as OTC medicines, alcohol consumption, and various other factors is highly recommended. Using liver-protecting supplements like Liv.52 can greatly help as well.  The Blast and Cruise Protocol, as with almost anything in this life, comes with Pros and Cons. Here are 3 most obvious and biggest Pros and 3 most obvious and biggest Cons: 

Advantages of blasting on cycle 

• Faster goals reach 
• Steady gains without interruption 
• No hormonal misbalance during the PCT cycle 

Disadvantages of blasting

• Commitment 
• You would require weekly injections for a long time 
• It may have a more negative impact on your health and organs

PCT after blasting and cruising 

Another very important thing to keep in mind is that when you would want to come off your entire blast and cruise cycle, then that can be quite a hard process since is hard to fully recover normally. This highly depends on how long you have been blasting and cruising too. Obviously – the longer you’ve been on your blasting and cruising cycle, then the harder is going to be to fully recover from it. 

This is the reason why many people who are not doing it professionally, opt for shorter blasting and cruising cycles. Professionals, usually, go for longer blast and cruise cycles as they have enough experience and knowledge on how to do it properly and how to fully recover easier. 

You might find online (on different steroid forums and blogs as well as other sources) various different strong protocols that are going to help you to recover back from a blast and cruise cycle. 

Despite the fact that many of them are indeed helpful, we need to warn you to do a lot of research on this first, that’s because there have been situations when users did not fully recover from their blasting and cruising. In some instances, this can be unhealthy, but it does come with negative side effects (nasty symptoms). 

Is very important for anyone to remember this when you consider starting the blasting and cruising protocol. While this can be super effective, is not meant for everyone. Only start one when you have enough experience with steroids and enough knowledge based on the research you’ve previously done. 

PCT (Post Cycle Therapy)

When coming off of a blast and cruise protocol, it is important to run a complete PCT protocol. Due to the amount of time these cycles last, it is vital that natural hormonal function is restored as quickly as possible. This means that you will need to use Clomid, Nolvadex, and hCG. Below I will place an example of this PCT protocol.

• Weeks 1 and 2, run 50mg of Clomid and 40mg of Nolvadex per day
• Weeks 3 and 4, run 25mg of Clomid and 20mg of Nolvadex per day
• Weeks 1, 2, and 3, run 1500IUs of hCG, 3 times per week (Monday, Wednesday, and Friday) 

As you can see from the information provided, there are pros and cons to running a blast and cruise protocol, just like there are pros and cons to a more traditional steroid cycle. The main factor to take into account is whether or not this type of cycle will benefit your goals. For a beginner, it is typically not advisable to run a blast and cruise, however, for the more experienced user, looking to maximize their progression, this could be the perfect way to do so. 

2 thoughts on “ Blast and Cruise protocols: Full overview on them and its benefits ”

I love Deca Durabolin. I’ve been using it for a few weeks and have already noticed incredible improvements. I feel wonderful, have more energy, and have more defined muscles. The advantages of blasting cycle with Deca Durabolin are just incredible.

If you’re looking for a way to blast through your workout plateau, the Blast and Cruise Protocol using Winstrol and Trenbolone is definitely worth trying. I was initially a little dubious, but now I’m convinced after experiencing the outcomes for myself. I worked out with more vigor and endurance and saw a change in my muscular definition afterward.

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Deca questions for Blasting + Cruising

• Thread starter Landmonster
• Start date Jul 11, 2013

Landmonster

• Jul 11, 2013
• If you're blasting and cruising, can you run Test and Deca upto the last day of the cycle? Or should you still end Deca earlier?
• Is Deca a smart drug to use on a cruise... even at 100mg/week? The purpose of this would be to retain muscle and protect joints, in addition to 150-200mg Testosterone. Is this just asking for health problems?

Well-known member

• Jul 12, 2013

I have seen some studys done on long term deca usage and they suggest that it is hard on your cardiovascular system so for that reason I cycle it. My cruise which lasts 8 to 10 weeks is 180 mg test C per wk with 4 to 6iu Gh per day My blast which lasts 16 to 20 weeks is as follows 800 to 1000 test C per wk 600 deca per wk along with sum dbol and epistane daily Ill up the GH to 6 or 8iu daily I adjust my dosages according to how I feel Im getting old soon it will be just low dose test and GH until im dead I always like to find out what others are using and try to figure out whats best for you  

As for your question about running the deca as long as test on blast that's fine because you really are not stopping your test injections u are simply lowering your dosage. The reason you stop deca before test is that it lingers in the bloodstream longer than test, so if you stop it at the same time the test leaves earlier and deca sticks around rendering your pct protocol useless do to the fact that the deca suppresses natural test levels and causes u to have to rebound naturally. Running deca for an extended amount of time has been shown to cause an enlarged heart and cardiovascular problems as someone already stated. I would not recommend this.  

ManoftheWorld

for cruising with deca, going at the 100-125/wk range for joint health, increased protein synthesis etc shouldnt cause you any issues hell with blood work you could maybe even get away with 150 or so /wk but for blasting due to deca's history of causing issues with enlarging heart valves with high doses over long periods and its long half life will just make your blast longer than you intend, blasting with NPP would probably be best idea on top of your cruise dose of reg deca... that way you will know the NPP will clear shortly after your done and your 8 week cruise due to long half life ends up being 10-12 weeks depending on how high of a dose you blast... this is all just IMO but when there are studies that link deca to heart issues I wouldnt take that lightly... use it but in moderation... 400/wk realistically when added to other AAS should do wonders if you cycled it but for blasts 400 isnt really all that high but still should work if you wanted to consider it, again just make sure there are other drugs for the added synergy, definitely a good amount of test and a dht based drug like mast, primo, drol, win, var etc to balance all the angles of AAS...  

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Iranian barrage of missiles and drones causes little damage, Israel says

What we know.

• Iran launched more than 300 cruise and ballistic missiles and drones at Israel, IDF officials said, a retaliatory attack weeks after an Israeli strike on the Iranian consular building in Syria killed two of Tehran’s top commanders.
• There were explosions visible in the air over Jerusalem as air sirens rang throughout the country.
• The U.S. and Israeli militaries shot down the “vast majority” of the missiles and dozens of attack drones. Some missiles struck a military base in the south, causing minor damage.
• A 10-year-old girl was severely injured by shrapnel, and about 31 people were treated for anxiety or injuries they sustained while heading to a protected area when sirens sounded.
• Iran said that after tonight's attack, the "matter can be deemed concluded" unless there is more violence.

This event has ended. Get the latest updates on Iran’s unprecedented attack on Israel here

Attack a 'grave threat to regional security,' E.U. foreign affairs chief says

Josep Borrell Fontelles, the U.N.'s high representative for foreign affairs and security policy, said in a post on X that it strongly condemns the Iranian attack against Israel.

Israel reopens its airspace

Paul Goldman

Richie Duchon

The airspace over Israel was reopened at 7:30 a.m. local time Sunday, a spokesperson for Israel's airport authority said in a statement.

Flights out of Tel Aviv were likely to change, and travelers should check with airlines and on the airport authority's website for updates to flight schedules.

Domestic airports would remain open throughout the day, the statement said.

Iran launched over 300 projectiles, Israeli military says

Rudy Chinchilla

Israel intercepted 99% of the more than 300 projectiles launched by Iran, and is ready for “any further developments and scenarios,” Israel Defense Forces spokesman Daniel Hagari said.

Among the projectiles were some 30 cruise missiles, none of which made it into Israel, Hagari said. Only a “few” of the more than 120 ballistic missiles launched entered Israel, with the rest being intercepted, he added.

Some of the ballistic missiles hit the Nevatim airbase, but they caused only minor infrastructure damage, and the base remained operational, Hagari said.

Iraq and Yemen also carried out launches against Israel, but none made it into the country, the IDF spokesman said. He added that “dozens” of rockets were launched from Lebanon toward the north of Israel, though Israel suffered no injuries or deaths and hit back by striking different targets in Lebanon.

A 10-year-old girl was severely injured by shrapnel, but there were no immediate reports of other Israeli injuries or deaths, Hagari said.

“Iran did something very serious, very severe this night, as it pushed the Middle East toward escalation. We will do whatever is necessary in order to defend the citizens of the state of Israel,” he said.

Netanyahu issues first public statement

Israeli Prime Minister Benjamin Netanyahu issued his first public comments since Iran's overnight attack, saying in a post on X, "We intercepted, we stopped. Together we will win."

U.S. destroyed 'dozens' of missiles and drones launched by Iran

Mosheh Gains

The U.S. military shot down "dozens" of missiles and drones en route to Israel, part of an "unprecedented" attack by Iran, Defense Secretary Lloyd Austin said in a statement late Saturday.

The aerial attacks by Iran were launched from Iran, Iraq, Syria and Yemen, he said.

"We condemn these reckless and unprecedented attacks by Iran and its proxies, and we call on Iran to immediately halt any further attacks, including from its proxy forces, and to deescalate tensions," Austin said in the statement. "We do not seek conflict with Iran, but we will not hesitate to act to protect our forces and support the defense of Israel."

Biden says he will coordinate a 'united diplomatic response' to Iran with G7 leaders

Doha Madani

President Joe Biden said he spoke with Israeli Prime Minister Benjamin Netanyahu tonight, reaffirming the United States’ commitment to the security of Israel.

Military forces followed Biden's direction to help Israel take down nearly all of the incoming drones and missiles, the president said. He also praised the country's ability to fend off attacks as a sign to others who threaten the security of Israel.

"Tomorrow, I will convene my fellow G7 leaders to coordinate a united diplomatic response to Iran’s brazen attack," Biden said. "My team will engage with their counterparts across the region. And we will stay in close touch with Israel’s leaders."

Though no U.S. forces have been attacked, Biden said America will "remain vigilant to all threats." He condemned the Iranian regime's attack tonight in the "strongest possible terms."

U.N. Secretary General condemns Iranian attacks

António Guterres, United Nations secretary-general, condemned the Iranian attacks on Israel tonight in a statement expressing concern over the serious escalation in the Middle East.

"I am deeply alarmed about the very real danger of a devastating region-wide escalation," Guterres said. "I urge all parties to exercise maximum restraint to avoid any action that could lead to major military confrontations on multiple fronts in the Middle East."

Guterres also condemned the April 1 attack on Iran's diplomatic premises in Damascus the day after it occurred.

He did not name Israel in that statement, which has not taken responsibility for the strike. Guterres emphasized the protection of diplomatic buildings and urged "all parties to respect all their obligations under international law."

U.N. Security Council to meet tomorrow

Rebecca Cohen

Yasmeen Persaud

The United Nations Security Council will meet Sunday following a request to hold an emergency meeting from Israel’s ambassador to the U.N.

The ambassador, Gilad Erdan, asked the council to condemn Iran's attack on his country and to designate the Iranian Revolutionary Guard Corps as a terror organization.

"The Iranian attack is a serious threat to global peace and security and I expect the Council to use every means to take concrete action against Iran," Erdan said in a post on X, which included the letter.

The meeting will take place at 4 p.m. ET, according to a U.N. schedule released tonight.

Iranian regime exercised 'its inherent right of self-defense' following diplomatic strike, foreign ministry says

The Iranian foreign ministry released a statement tonight reiterating its position that the strikes carried out against Israel were "in exercise of its inherent right of self-defense."

“The Islamic Republic of Iran would not hesitate to take further necessary defensive measures to protect its legitimate interests against any act of military aggression or unlawful use of force,” the statement said.

The ministry cited Article 51 of the United Nations charter and said that it was responded to Israeli's "recurring military aggressions," including the strike of Iran's diplomatic building in Syria earlier this mont.

The statement went on to say that its response was a "responsible approach" amid Israel's "apartheid" against Palestinians and "military aggressions" against neighboring states.

U.S. concerned Israel will respond to Iran without thought to potential fallout

Courtney Kube

Carol E. Lee Carol E. Lee is the Washington managing editor.

Some top U.S. officials are concerned Israel could do something quickly in response to Iran’s attacks without thinking through potential fallout afterward, according to a senior administration official and a senior defense official.

Those concerns stem in part from the administration’s views of the approach Israel has taken to its war against Hamas, as well as the attack in Damascus. 

President Joe Biden has privately expressed concern that Israeli Prime Minister Benjamin Netanyahu is trying to drag the U.S. more deeply into a broader conflict, according to three people familiar with his comments. 

The White House believes Israelis are not looking for a wider war or a direct war with Iran, but U.S. officials can’t be certain, the senior administration official said.

U.S. officials have privately expressed frustration with Israel’s decision to strike the Iranian consular building in Syria.

“I don’t think they had a strategy,” the senior administration official said. “The Israelis don’t always make the best strategic decisions.”

Senior leaders at the Pentagon also have privately expressed frustration at the timing of the Damascus strike, according to the senior defense official, because it had the potential to be “catastrophically escalatory.”

Netanyahu and Biden speaking

Yarden Segev

Prime Minister Benjamin Netanyahu is currently talking with President Joe Biden, according to a spokesperson for Netanyahu.

Their conversation follows discussions by the political-security cabinet and the war management cabinet, the spokesperson said.

Netanyahu's office did not disclose what the leaders discussed.

Israeli in Tel Aviv describes fighter jet sonic booms and explosions

Anna Schecter

Barak Herscowitz is hunkering down at home in Tel Aviv listening to what sounds him like a major war.

"The only sounds you hear, in a city where you would usually hear music from a nearby bar, is of fighter jets and explosions- no other sound," Herscowitz said.

Herscowitz, 38, said he is not in his safe room yet, and is feeling grateful for Israel's missile defense technology.

Hercowitz was just 7 years old when the Persian Gulf war broke out.

"I remembered today how we didn’t really have many ways to defend ourselves from both threats of that time: massive conventional missiles with mass destruction potential, and chemical weapons," he said. "This time, we have very strong air defense, almost all of the citizens have shelters in their homes — so for me, the feeling is much safer."

His real fear is for the long term: "This escalation is worrying mostly because it is unclear if Iran is dragging us to a much wider, longer and harder war on all fronts.” 

Hercowitz said he feels Israelis are resilient following more than six months of rocket fire from Iranian proxies.

"Although tonight is filled with an anxiety and I believe that no Israeli will sleep soundly, I’m optimistic we will get through these days in piece and the air defense will continue to work," he said.

Israeli security services say it treated 31 people

Israeli emergency services have been dispatched to treat 31 people who suffered from anxiety or minor injuries after emergency sirens blared throughout the country.

A statement from Magan David Adom noted that the injuries were caused "on their way to the protected area." It said it "continues to be on high alert."

A 7-year-old girl from the Bedouin diaspora was also in serious condition, but the cause of her injury is being investigated by police.

McConnell calls on House to pass national security supplemental amid Iran's barrage

Julie Tsirkin

Carly Roman

Senate Minority Leader Mitch McConnell called out the Republican-controlled House's inaction on a Senate-passed aid package for Israel and Ukraine after Iran launched an aerial attack against Israel tonight.

“Congress must also do its part," McConnell, a Kentucky Republican, said.

"The national security supplemental that has waited months for action will provide critical resources to Israel and our own military forces in the region. It will provide overdue lethal assistance to Ukraine and equip vulnerable allies and partners in Asia to deter the PRC. And it will make urgent investments in our own defense industrial base," he continued.

McConnell also urged President Joe Biden and Congress to "discharge our fundamental duties without delay." He did not elaborate on which duties he was referencing.

Biden has repeatedly said he will defend Israel against Iran and the U.S. is shooting down some drones flying toward Israel.

Richard Engel NBC News Chief Foreign Correspondent, Host of MSNBC's "On Assignment with Richard Engel"

JERUSALEM — Israel and Iran have been at odds for decades, but what we're seeing tonight is different. Iran is directly attacking Israel, instead of hiding behind proxies or using another militant group to attack Israel, therefore, inviting Israel to retaliate directly on Iranian territory.

It's important that Iran said that after this attack, it wants the conflict to be over, but to be determined is whether Israel, and Prime Minister Benjamin Netanyahu, agrees with that.

The drone attacks in Israel were the first wave of what Iran has said would be a three-wave attack. The second wave is comprised of more drones and missiles, and the third wave is ballistic missiles, which has the biggest potential to escalate this conflict into a regional war between Iran and Israel.

Many of Iran's strikes appear to be focused in southern Israel, in the Negev Desert area, where drones and missiles appear to have gotten through the air defense system.

Israeli media reported that some of the drones appeared to target the Knesset building in Jerusalem.

Biden's Situation Room meeting concludes

Kelly O'Donnell

Elyse Perlmutter-Gumbiner

President Joe Biden’s meeting with principals of the National Security Council in the White House Situation Room has concluded, per a senior administration official. It was roughly two hours long.

200 drones, missiles fired toward Israel: IDF

Over 200 different kinds of missiles and drones — including killer drones, ballistic missiles and cruise missiles — have been fired toward Israel in the Iranian attack that launched just hours ago, Israel Defense Forces spokesperson Rear Adm. Daniel Hagari said.

He called the attack a "wide scale escalation" and said the IDF is operating at "full force" to protect the people of Israel.

Hagari said the vast majority of drones and missiles have been intercepted outside of Israel’s borders with the help from Israeli allies. The U.S. said it has intercepted a number of drones.

A number of missiles were dropped inside Israeli territory, causing damage to a military base, Hagari said, adding that there were no reported casualties beside a girl who was hurt. He added, "we hope she will be well."

"We are ready for any threat that will come to Israel, we will do everything we need, everything, to defend the state of Israel," Hagari said.

U.S. politicians weigh in on Iran attack against Israel

After Iran launched hundreds of drones in an attack on Israel, House Speaker Mike Johnson said, “America must show our full resolve to stand with our critical ally."

Johnson, R-La., said Israel is not alone and assured he will work with the White House "to insist on a proper response."

He also called out the Biden administration, placing some blame on it for the attack.

"The Biden administration’s undermining of Israel and appeasement of Iran have contributed to these terrible developments," Johnson said.

Other politicians reiterated Israel's right to defend itself against such an attack and pledged U.S. support.

Sen. Roger Wicker, R-Miss., the top Republican on the Senate Armed Services Committee, said the U.S. commitment to Israel is “unwavering.”

“ This is the moment for the United States to show we stand together with our allies,” the senator said. “Our shared enemies, including Iran and their proxies, need to know our commitment is unwavering.”

Sen. Ben Cardin, D-Md., chairman of the Senate Foreign Relations committee, said in a statement to NBC News that “Israel has an inherent right to defend itself against these attacks from Iran and its proxies — before, during, and after they occur.”

Cardin, somewhat opposing Johnson's stance, said he supports President Joe Biden’s “iron-clad commitment to Israel’s security” and thanked his administration for taking what he said were necessary steps in recent days to support Israel as it prepared for an attack from Iran.

He reiterated that “the United States will continue to stand with Israel" and cautioned "Iranian regime leaders to not widen this already ill-conceived attack. Such escalation, especially targeting U.S. personnel and assets, should be dealt with swiftly and decisively.”

Others warned the attack could be far more extensive than it was initially thought to be.

Sen. Marco Rubio, R-Fla., the top Republican on the Senate Intelligence Committee, said on X , “The attack on #Israel by the regime in Iran is going to be more extensive than initially expected.”

So far, the U.S. has intercepted some drones launched at Israel and is working to do the same for incoming missiles.

Trump sounds off on Iran attack

Former President Donald Trump sounded off on the Iran attack on Israel at a rally in Pennsylvania tonight.

He told the crowd the attack was a product of American weakness.

"That's because we show great weakness," he told the crowd at the Schnecksville Fire Company fairgrounds. "This would not happen. The weakness that we've shown, it's unbelievable and it would not have happened if we were in office."

Trump added that "America prays for Israel" as Iranian missiles were fired toward the country.

Later on, members of the crowd could be heard chanting, "Genocide Joe! Genocide Joe!" to which Trump responded, "They're not wrong."

President Joe Biden has repeatedly said he will defend Israel against Iran and the U.S. is shooting down some drones flying toward Israel.

But his defense of the Jewish State has attracted criticism from some corners of his party, even pointing out on one occasion that some protesters who were chanting that he was “complicit in genocide” in Gaza "have a point.”

Rockets and flares burst across sky above Jerusalem

JERUSALEM — Israel's air defense systems appeared to be fully engaged in the early morning hours here. The dark skies above the Old City of Jerusalem intermittently lit up with orange flares as Israeli rockets appeared to be taking out incoming Iranian drones.

U.K. moves resources to Middle East to ‘encourage de-escalation’ of attacks

Andrew Jones

The U.K. is moving Royal Air Force jets and air refueling tankers to the Middle East "to encourage de-escalation and prevent further attacks," the Ministry of Defense said in a statement.

The statement said the jets from the U.K. will intercept airborne attacks near existing missions by the country.

"We will continue to cooperate closely with our regional partners in the interest of de-escalation," the ministry statement said.

Biden meets with national security team

President Joe Biden said in a post on X this evening that he met with his national security team to discuss Iran's attack against Israel.

Biden cut short a trip to Delaware to return to the White House today.

Rocket fire streaks across sky as air-raid sirens blare in Jerusalem

Daniel Arkin

JERUSALEM — The dark sky above the Old City of Jerusalem lit up tonight with orange flashes of rocket fire as air-raid sirens rung out across the city.

The bursts of rocket fire resembled shooting stars and appeared to come from Israel's sophisticated air defense system, not the Iranian drone attacks.

Iran fired missiles at Israel, U.S. official says

A U.S. official confirmed that Iran fired missiles at Israel and that the U.S. military is trying to shoot down Iranian missiles and drones bound for Israel.

The U.S. has shot down several Iranian drones but does not have confirmation that it has successfully shot down missiles. 

House schedule to change next week in light of Iran's attack on Israel

The House's schedule will change for next week, said Rep. Steve Scalise, the House Republican majority leader, and it will refocus on considering legislation to support Israel and hold Iran accountable.

"In light of Iran’s unjustified attack on Israel, the House will move from its previously announced legislative schedule next week to instead consider legislation that supports our ally Israel and holds Iran and its terrorist proxies accountable," Scalise said.

As Iran launches a retaliatory attack against Israel, former NBC News Tel Aviv bureau chief Martin Fletcher reports on how the Israeli air defense systems are prepared to stop certain attacks, but explains why the ballistic missiles may still break through.

Iran says attack in response to 'Zionist regime’s aggression' has concluded

Iran said it conducted a military attack on Israel "in response to the Zionist regime’s aggression against our diplomatic premises in Damascus," and that "the matter can be deemed concluded."

The Permanent Mission of the Islamic Republic of Iran to the U.N. said in a post on X that if Israel makes "another mistake, Iran's response will be considerably more severe," and that the matter is between Iran and Israel, and that the U.S. should stay out of it.

It said the attack was "legitimate defense" in response to the suspected Israeli attack on the Iranian consular building in Syria and was "conducted on the strength of Article 51 of the UN Charter."

The drones, launched hours ago, are beginning to arrive in Israel.

Sirens sound throughout Israel

Raf Sanchez

Yael Factor

TEL AVIV, Israel — Sirens have sounded across Israel — in southern and northern Israel, and the areas of Shomron, the Dead Sea and Jerusalem, the IDF confirmed.

The sirens all sounded in the span of about three minutes.

Residents of the northern Golan Heights, as well as the areas of Nevatim, Dimona and Eilat, have been told by the Israel Defense Forces they are required to stay near protective spaces until further notice.

The IDF said residents are required to enter a protected space when sirens are activated. If there is no protected space, residents must find the most protected area possible and wait 10 minutes, it said.

U.S. military has shot down Iranian drones

The U.S. military has shot down some Iranian drones tonight, according to U.S. officials.

The military intends to shoot down Iranian drones and missiles when they come into range of U.S. assets in Iraq, Syria and at sea.

The U.S. has beefed up its air defenses in recent months since the attack on Tower 22 and has repositioned assets in the region to be ready for this Iranian attack.

NYPD says no credible threats to city

Matt Johnson

Iranian attack is 'severe and dangerous escalation': IDF spokesperson

Jay Marques

Iran launching drones toward Israel "is a severe and dangerous escalation," IDF spokesperson Daniel Hagari said in an English video announcement.

Hagari said the IDF is "closely monitoring Iranian killer drones that are en route to Israel sent by Iran."

"Our defensive and offensive capabilities are at the highest level of readiness ahead of this large-scale attack from Iran," Hagari continued. "Together with our partners, the Israel Defense Forces is operating at full-force to defend the state of Israel and the people of Israel."

He said, "This is a mission that we are determined and ready to fulfill."

Biden to meet Iraq's prime minister on Monday

Dennis Romero

President Biden is expected to meet with Iraq's prime minister, Mohammed Shia al Sudani, on Monday in Washington in a face-to-face discussion that has been on the president's schedule for weeks.

Their topic of discussion pertains the scope of U.S.-Iraq relations, including military presence and trade.

According to the D.C.-based military think tank Institute for the Study of War , the Islamic Resistance in Iraq could resume attacks after a monthslong pause.

The militia, including other Iran-backed groups, want the United States to leave Iraq, and the meeting could produce a crucial moment during which anti-Western forces decide whether the goal of U.S. troop withdrawal has any traction, the institute said in a critical threats update on Friday.

The think tank cites remarks by Qais Khazali, secretary general of an Iran-backed militant group, Asaib Ahl al Haq, who is said to have warned of renewed attacks if the Biden meeting doesn't result in a U.S. troop withdrawal.

Those attacks on U.S. forces in Iraq were paused in February amid talks between Washington and Baghdad on the size and shape of the United States' presence in Iraq. The wider array of Iran-backed militias in the region, the Iran-named "Axis of Resistance," rejects any plan that includes a U.S. military presence in Iraq.

At the same time, Iraq's Al Sudani has proposed deeper economic, agricultural, industrial, technological and energy ties to the United States.

A group of GOP lawmakers is decrying the Biden-Al Sudani meeting, saying in a letter last month it represents "appeasement of Iran," given the country's influence in Iraq.

Sen. Chuck Schumer said the U.S. stands with Israel

"As Israel is under attack from Iran, we stand with Israel and its people, and the United States will do everything we can to support Israel’s defense against Iran," Senate Majority Leader Chuck Schumer, D-N.Y., said in a post on X .

Schumer is the highest-ranking Jewish official in the U.S.

He recently called for new elections in Israel to replace Prime Minister Benjamin Netanyahu.

Netanyahu convening war Cabinet

Israeli Prime Minister Benjamin Netanyahu is convening the war management Cabinet in Kirya in Tel Aviv, his office said.

Earlier today, before Iran launched hundreds of drones toward Israel, Netanyahu said the country has been preparing for the possibility of a direct attack from Iran in recent years and weeks.

"Our defense systems are deployed, we are prepared for any scenario, both in defense and attack," Netanyahu said. "The state of Israel is strong, the IDF is strong, the public is strong."

He said he appreciated the U.S. "standing by Israel's side," as well as Great Britain, France and "many other countries."

"I established a clear principle — whoever hurts us, we hurt him. We will protect ourselves from any threat and we will do so with coolness and determination," Netanyahu said. "Together we will stand, and with God’s help — together we will overcome all our enemies."

Biden back at the White House

Caroline Kenny

President Joe Biden arrived at the White House and was headed into the Oval Office at approximately 5:04 p.m. ET.

He is to meet with principals of the National Security Council to discuss the situation in the Middle East in the Situation Room, the White House said.

Biden cut short a trip in Rehoboth Beach, Delaware, where he was expected to spend the weekend.

X users circulate misleading videos amid Iran attack on Israel

Janhvi Bhojwani

When news broke that Iran had launched a retaliatory attack on Israel, some users on the social media platform X uploaded misleading videos, including footage from previous drone attacks or imagery from video games.

In one, an X user posted a video from six months ago showing Israel’s Iron Dome air defense system intercepting Hamas rockets in Ashkelon. In another post flagged by a reporter for the BBC, an X user falsely suggested that imagery from the video game “Arma 3” was video from today’s drone attacks.

Iran launches attack on Israel that risks sparking regional war

Dan De Luce

Aurora Almendral Aurora Almendral is a London-based editor with NBC News Digital.

Iran launched a retaliatory attack against Israel on Saturday that risks sparking a regional conflict that could draw in U.S. military forces. The attack marked the first time that Iran has launched a direct military attack on the Jewish state. 

Israeli military officials said the attack began with more than 100 Iranian drones heading toward Israel. It will take hours before the drones arrive, and Israeli officials said they hope to intercept them.

A senior Biden administration official warned that the assault could also involve dozens of cruise missiles and ballistic missiles. 

The official said the administration expects Israeli government facilities to be targeted but not civilian or religious sites. U.S. assets in the region are also not expected to be targeted, the official said.  

The U.S. and Israel have been closely coordinating how to defend against the attack, the official said. “We’re ready. The Israelis are ready.”

Read the full story here.

Israel has 'tens of aircraft' in Israel airspace: IDF

The Israeli Defense Forces have "tens of aircraft" in Israeli skies at the moment, an IDF official said at a briefing following Iran's launching of drones toward Israel.

The IDF confirmed the launching of drones but said it cannot confirm that Iran has launched any missiles. The official said the IDF cannot confirm the type or the payload of drones launched.

The official also said they cannot confirm if there have been any interceptions yet or what Iran is targeting in Israel.

The IDF is operating on "a pre-prepared action plan," the official said, adding that the idea is to intercept the drones before they reach Israel but that they will intercept the drones over Israel if necessary.

Congressional intelligence committees received classified info on Iran's plans

Members of the House and Senate intelligence committees had classified information made available to them last week on Iran’s plans to strike Israel, two congressional officials told NBC News.

The officials said they expect briefings from administration and intelligence community officials next week when Congress returns, but those briefings have not yet been scheduled.

Lebanese airspace is closed

Lebanese airspace has been closed to all arriving, departing and crossing aircraft, Ali Hamiyah, the minister of public works in the caretaker government, said in a post on X, in light of the attacks launched from Iranian territory toward Israel.

The closure is temporary, the government said, and will start at 1 a.m. local time and will be in effect until 7 a.m. local time.

Air traffic at Beirut Rafic Hariri International Airport will be completely closed during the same time period, according to the statement. Updates will be made according to developments in the situation.

U.K. Prime Minister Rishi Sunak condemns Iranian attack toward Israel

"I condemn in the strongest terms the Iranian regime’s reckless attack against Israel. These strikes risk inflaming tensions and destabilising the region," U.K. Prime Minister Rishi Sunak said in a statement.

"Iran has once again demonstrated that it is intent on sowing chaos in its own backyard," Sunak added.

Sunak said the U.K. will continue to "stand up for Israel’s security" as well as that of the U.K.'s regional partners, including Jordan and Iraq.

"Alongside our allies, we are urgently working to stabilise the situation and prevent further escalation. No one wants to see more bloodshed," Sunak said.

Israeli airspace closing to all domestic and international flights

Israel's airspace will be closed to all domestic and international flights starting at 12:30 a.m. local time, a spokesperson with the Israel airport authority said.

The spokesperson said the flight schedule from Tel Aviv is likely to change due to the delay in the arrival of flights to Israel and that the Ramon Airport will be closed to traffic.

Travelers should check with airlines and on the Airports Authority website regarding new flight times, according to the spokesperson, who said they will continue to provide updates as the situation develops.

El Al cancels 15 flights

El Al has canceled 15 flights, a spokesperson for the airline confirmed to NBC News. The canceled flights were mainly from Europe to Israel.

"In light of the closure of the airspace over Israel, some El Al flights are canceled," a statement from the airline said.

Updates will be posted on El Al's website and on social media. Customers whose flights were canceled will be notified when they can book an alternative when possible.

"El Al operates according to the instructions of the security forces and is in direct contact with them," the spokesperson said.

More than 100 UAVs launched toward Israel

More than 100 unmanned aerial vehicles were launched toward Israel, the IDF confirmed to NBC News.

U.S. bracing for 'major attack' in Israel

Now that Iran has begun its retaliation against Israel, the U.S. is bracing for this to be “a major attack,” according to two senior U.S. officials.

The administration’s expectation is Iran will launch more than 100 drones, dozens of cruise missiles and dozens of ballistic missiles targeting Israeli government sites, not civilians or religious sites, one of the officials said.

The U.S. and Israel have been closely coordinating on a defense against the attack. “We’re ready. The Israelis are ready,” the official said.

Commander of U.S. Central Command Gen. Michael “Erik” Kurilla was in Israel for a meeting with senior Israeli officials for the past several days, and now defense officials say he is traveling in the region. During his visit, Kurilla consulted with the Israelis on a defense plan that includes U.S. help from the sea and air, as well as how Israel might respond to Iran’s attack, the senior U.S. officials said.

The administration is not expecting Iran to target any U.S. assets in the region, the officials said.

IDF says Iran has launched attacks on Israel

Israeli Defense Forces spokesperson Hagari said in a televised statement in Israel today that "Iran launched unmanned aircrafts from its territory towards the territory of the State of Israel."

He reiterated that the threat will take "several hours" to reach Israel and that the IDF and the Israeli Air Force are implementing their plan that has been prepared for this moment.

He noted that if the threat is determined to arrive sooner than expected, updates will be provided.

In a separate statement, the IDF said Iran "launched UAVs from within its territory toward Israel," adding that the IDF, including the IDF Aerial Defense Array, is on "high alert and is constantly monitoring the operational situation," as are IAF fighter jets and Israeli Navy vessels.

The IDF is also monitoring all targets, it said. Hagari said they are also monitoring the threat in the airspace.

Hagari urged Israelis to be "vigilant" and to follow directives in accordance with the plans.

"We know these threats and have dealt with them in the past. If an alert is activated in the area where you are, you must enter the protected area and stay here for at least 10 minutes," Hagari said to the Israeli people. "We will update you if you are required to stay in the protected area for a longer time."

He said Israelis will be given updates and be notified of any changes in the situation from the IDF and the Home Front Command.

"Continue to behave responsibly and calmly, as you have done so far, be careful and act according to the instructions," Hagari said.

He added: "The IDF is prepared and ready for all its formations in defense and attack. We prepared for a variety of scenarios in advance. We work in close cooperation with the U.S. and our partners in the region to act against the launches and intercept them."

"But remember," Hagari warned, "the protection is never hermetic. That is why it is very important to follow the instructions and obey the instructions of the Home Front Command, they save lives."

Biden to meet with principals of the NSC on Iran attacks

President Biden will meet with principals of the National Security Council to discuss the situation in the Middle East in the White House Situation Room, the White House said.

Earlier today, Biden was briefed on the matter by national security adviser Jake Sullivan and principal deputy national security adviser Jon Finer, according to the White House.

They will later meet with Defense Secretary Lloyd Austin, Secretary of State Antony Blinken, Chairman of the Joint Chiefs of Staff Gen. Charles Q. Brown, CIA Director Bill Burns, Director of National Intelligence Avril Haines, counselor to the president Steve Ricchetti and National Security Council Coordinator for the Middle East and North Africa Brett McGurk.

Vice President Kamala Harris and chief of staff Jeff Zients will also attend the meeting virtually by secure video, the White House said.

The U.S. military is ready to help defend Israel in attacks from Iran that are expected to last for hours

Iran has begun its retaliatory strikes against Israel, according to three U.S. officials.

The attacks are beginning with drones, the officials said, but they expect Iran to launch missiles as part of what is expected to be an hourslong operation that is now expected to last late into the night.

The U.S. is prepared to help defend Israel with ships, including the USS Carney, a destroyer that has been involved in shooting down Houthi projectiles but is now repositioned to help Israel, as well as other destroyers and assets, the officials said.

NSC confirms 'airborne attacks on Israel'

Allie Raffa

NSC spokesperson Adrienne Watson confirmed in a statement that Iran has launched its “airborne attacks on Israel.”

President Joe Biden is being updated about the situation in the Middle East by his national security team and plans to meet with them this afternoon at the White House, the statement said.

Additionally, Biden's team is in "constant contact" with Israeli officials, partners and allies.

The attack on Israel is likely "to unfold over a number of hours," Watson said in the statement.

"President Biden has been clear: our support for Israel’s security is ironclad," the statement said. "The United States will stand with the people of Israel and support their defense against these threats from Iran."

Iran supreme leader had warned that Israel would be 'punished'

Earlier this week, Iran’s supreme leader,  Ayatollah Ali Khamenei , said at a prayer ceremony celebrating the end of the holy month of Ramadan that Israel “must be punished, and it will be punished.” His remarks were broadcast by Iranian state TV.

His comments came after Israel’s Foreign Minister Israel Katz said on X that his country “will respond and attack in Iran” if it attacked from within its territory.

Iran launches drones toward Israel

Iran has launched drones toward Israel, IDF spokesman Daniel Hagari said in a statement, in an attack that Tehran had promised to carry out after its embassy in Damascus was hit last week.

U.S. restricts travel for Israel staff as Iran attack fears rise

Yuliya Talmazan

The United States has restricted travel for its staff in  Israel , as fears grow of an imminent retaliatory attack by  Iran .

The U.S. Embassy in Jerusalem issued  a security alert Thursday  restricting its employees and their family members from personal travel outside the greater Tel Aviv, Jerusalem and Be’er Sheva areas until further notice “out of an abundance of caution.”

Israel threatened to strike Iran directly if it launches attack from its territory

The Associated Press

Israel’s foreign minister threatened Wednesday that his country’s forces would strike  Iran  directly if the Islamic Republic launched an attack from its territory against  Israel .

“If Iran attacks from its territory, Israel will respond and attack in Iran,” Israel Katz said in a post on X in Farsi and Hebrew.

Middle East latest: Israel 'unlikely to launch strike on Iran until after Passover'; EU steps up Iranian sanctions

US sources have reportedly said Israel is unlikely to attack Iran until after the major Jewish holiday ends later this month. Meanwhile, the European Union has decided to take "further restrictive measures" against Tehran.

Thursday 18 April 2024 06:56, UK

• Israel-Hamas war

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• Qatar 're-assessing its role as mediator' as talks hit stumbling block
• Striking Iran's nuclear facilities on the table, says ex-Mossad official
• Israel considered Iran strike on Monday but decided to wait - report
• 'Tiniest move' against Iran will spark 'fierce and painful' response, president warns
• Dominic Waghorn analysis: The coming hours could decide whether the Middle East is plunged into a widening war
• Michael Clarke analysis: All Israel's options for retaliation come with complications
• Live reporting by Jess Sharp

Israel is unlikely to launch an attack on Iran until after Passover, ABC News has reported. 

The news outlet cited an unnamed senior US official as saying that was the case. 

Passover is a major Jewish holiday that celebrates the biblical story of the Israelites' escape from slavery in Egypt. 

It begins on Monday and ends after nightfall on 30 April. 

The official also said the Iranian Islamic Revolutionary Guard Corps and other leadership were still on a high state of alert, with some in safe houses and underground facilities. 

It comes after Axios cited five Israeli and US sources as saying Israel considered a near-immediate response to Saturday's attack by Iran, but decided against it. 

Israel considered conducting retaliatory action on Monday night, before eventually postponing it, the news outlet reported. 

Sky News has not been able to verify either report. 

Israel's foreign minister has welcomed the news we heard overnight that the European Union leaders have decided to step up sanctions against Iran.

Israel Katz said the decision was an "important step on the way to removing the snake's teeth". 

"Thanks to all our friends for their support and assistance. Iran must be stopped now before it is too late." 

The EU's move comes after Tehran's missile and drone attack on Israel left world powers desperately scrambling to prevent a wider conflict in the Middle East.

The bloc's 27 national leaders condemned the Iranian attack, reaffirmed their commitment to Israel's security and called on all sides to prevent more tensions, including in Lebanon.

Two Hezbollah militants have been killed in Lebanon, the Israel Defence Forces has said. 

In a post on Telegram, the Israeli military said it struck targets related to the Lebanese militant group overnight. 

Fighter jets hit the "terror targets" in Khiam, including infrastructure and two military structures, it added. 

"Furthermore, IDF soldiers fired in order to remove an imminent threat in the area," it said. 

"Moreover, an Israel air force aircraft eliminated two Hezbollah terrorists identified in the area or Kfarkela." 

The IDF and Hezbollah have regularly exchanged in fire across the border, but attacks have increased since Israel launched its military operation in Gaza. 

Hezbollah, like Hamas, is backed by Iran. 

Hello and welcome back to our coverage of the Israel-Hamas war and wider tensions in the Middle East. 

We're still waiting to see if Israel will respond to Iran's massive aerial assault at the weekend - and what that might look like. 

Here are the key events from the past 24 hours to make you aware of:

• Qatar said it was re-assessing its role as a mediator in the conflict as talks hit a stumbling block;
• At least 14 Israeli soldiers were injured by Hezbollah airstrikes; 
• The former director of intelligence at the Israeli spy agency, Mossad, said targeting nuclear facilities in Iran was among the options on the table as Israel decides how to respond to Saturday's attack;
• Lord Cameron said during a visit to Israel it was "clear" that Benjamin Netanyahu's government will respond;
• Meanwhile, Iran's president warned the "tiniest move" against the country would bring a "fierce" response, according to state media;
• On aid for Gaza, the UN said Israel denied "more than 40%" of its aid delivery requests to northern parts of the enclave last week;
• It emerged that a single Israeli shell destroyed more than 4,000 embryos when it struck Gaza's largest fertility clinic in December.

We'll be back later this morning with more news and analysis from the Middle East.

European Union leaders have decided to step up sanctions against Iran.

The move comes after Tehran's missile and drone attack on Israel left world powers desperately scrambling to prevent a wider conflict in the Middle East.

The EU's 27 national leaders met in Brussels earlier - the first time the group has met since Saturday's attack.

They condemned the Iranian attack, reaffirmed their commitment to Israel's security and called on all sides to prevent more tensions, including in Lebanon.

"The European Union will take further restrictive measures against Iran, notably in relation to unmanned aerial vehicles (UAVs) and missiles," they said in a joint statement.

These images show an Israeli Sa'ar-6 corvette warship patrolling the waters of the Israeli city of Eilat. 

The vessel is believed to be carrying an Iron Dome anti-missile system - one of a reported 10 that Israel owns and operates to defend its skies. 

Italy's foreign minister says Rome would be willing to contribute troops to any possible United Nations peacekeeping force in Gaza, even though no such proposal is on the table and Israel has previously rejected the idea.

In an interview with AP, Antonio Tajani suggested that a UN force under Arab command could help provide security if Israelis and Palestinians made headway on an eventual two-state solution. 

"If there is the solution and for a short time we need the presence of the United Nations under Arab control, we are ready for sending Italian soldiers," Mr Tajani said ahead of a G7 foreign ministers meeting in Capri.

Israeli Prime Minister Benjamin Netanyahu has in the past ruled out a foreign peacekeeping force in Gaza after the war, saying only Israel is capable of keeping the territory demilitarised.

By Alex Crawford , special correspondent 

Lebanon is balanced as though on an earthquake faultline right now - whatever Israel decides to do next will have massive repercussions throughout the entire region.

That's how critical the situation is in Lebanon and the surrounding countries, as described by one seasoned Lebanese political analyst.

Khodor Taleb is also the former adviser to three different Lebanese prime ministers, so knows a thing or two about what is at stake.

Lebanon - like the entire region - is at the crossroads and it is Israel in the driving seat over which road is travelled.

'The situation will be totally out of control'

"I can tell you 100% that Hezbollah do not want war. The ball is in the Israeli court," Mr Taleb told Sky News.

The militant group Hezbollah is backed by Iran and has strong ties with both the Iranian leadership and the Islamic Revolutionary Guards Corps (IRGC).

It is very much seen as the strongest and most powerful of Iran's proxies which operate in multiple countries.

It is therefore potentially in the Israeli crosshairs as it considers how or whether to retaliate against Iran and its network in response to the missile and drone attacks at the weekend.

Mr Taleb is not an isolated voice in warning that an Israeli attack could tip the region into all-out war.

"It will be a huge risk for Israel because it will lead to a big war in the region," he said.

"It will not be limited to Lebanon. It will definitely spread to Yemen and most probably to the Syrian Golan and the situation will be totally out of control of any international power," he continued.

"It will be damaging to the whole region."

His point: Any large-scale Israeli attack against the Lebanese Hezbollah or Iran risks drawing the entire so-called Axis of Resistance into war - and that would involve the Yemeni Houthis, the Iraqi Hezbollah and the various Syrian militias - all of which have links to Iran or Hezbollah.

Read more of Crawford's piece here ....

The funeral for Hezbollah commander Ismail Yusaf Baz has been held in Chehabiyeh, Lebanon. 

The head of the militant group's coastal sector was "eliminated" in a strike in the Ain Ebel area yesterday, the Israel Defence Forces said.

As we reported in our 8.39pm post, Hezbollah responded today by launching missiles and drones at a military facility in northern Israel - injuring some 14 IDF troops. 

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